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Job DescriptionP39298
Confidence100.00%DateThu Jan 5 11:59:04 GMT 2012
Rank3Aligned Residues238
% Identity14%Templatec2g5tA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20. ........30.........40 .........50.........60.........70.....
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Query Sequence  IEIESRELADIPVLHAYPVG. QKDTPLPCVIFYHGFTSSS. . . . . LVYSYFAVALAQAGLRVIMPDAPDHGSRFSGDAAR
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Template Sequence  LDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHA
Template Known Secondary structure  TT
TT

TTS



TT




S



STT



TT
SSS
GG
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   514.....520.........530.........540.........550.........560.........570.........580.........590...
 
   76...80.........90.........100.........110.........120......... 130.........140.........150....
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Query Sequence  RLNQFWQILLQSMQEFTTLRAAIAEENWLLDDRLAVGGASMGAMTALGITARHP. TVRCTASMMGSGYFTSLARSLFPPL
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Template Sequence  INRRL. . . GTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE. . . . . YYDSV
Template Known Secondary structure  GTT
T...TSTTSSSTTS




SS



GG.....GSB
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   594.... .600.........610.........620.........630.........640.........650.........660 .....
 
   155....160.........170.........180.........190.........200.........210.........220.........230....
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Query Sequence  IPETAAQQNEFNNIVAPLAEWEATNHLEQLSDRPLLLWHGLDDDVVPADESLRLQQALSETGRDKLLTCSWQPGVRHRIT
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Template Sequence  YTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVD. . FQAMWYTDEDHGIA
Template Known Secondary structure 

SSTTTTT
SGGGGGGGGGSTT
SSS
T

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TT

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   666...670.........680.........690.........700.........710.........720......... 730.........740...
 
   235....240.........
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Query Sequence  . . . . . PEALDAAVTFFRQHL
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Template Sequence  SSTAHQHIYTHMSHFIKQCF
Template Known Secondary structure  S
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   744.....750.........760...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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