|   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | H | I | L | T | N | S | P | A | M | M | D | I | C | K | D | T | A | K | I | . |
. |
. |
. |
. |
. |
. |
. |
A | L | S | Q | A | S | V | L | I | S | G | E | S | G | T | G | K | E | L | I | A | R | A | I | H | Y | N | S | R | R | A | K | G | P | F | I | K | V | N | C | A | A | L | P | E | S | L | L | E | S | E | L |
Query Conservation |   |
  |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |
|
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |   | . | . | . |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | G | I | I | K | W | G | D | P | V | T | R | V | L | D | D | G | E | L | L | V | Q | Q | T | K | N | S | D | R | T | P | L | V | S | V | L | L | E | G | P | P | H | S | G | K | T | A | L | A | A | K | I | A | E | E | S | . |
. |
. |
N | F | P | F | I | K | I | C | S | P | D | K | M | I | G | F | S | E | T | A | K |
Template Known Secondary structure |   |
T |
|
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
| S |  |  |  |  |  |  |  |
| S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | T |
| S |  |  |  |  |  |
| G | G | G |
| T | T |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
513 | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | |
|
|
. | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . |
  |
  |   |
215 | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | G | H | E | K | G | A | F | T | G | A | Q | T | L | R | Q | G | L | F | E | R | A | N | E | G | T | L | L | L | D | E | I | G | E | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | L | V | L | Q | A | K | L | L | R | I | L | Q | E | R | E | F | E | R | I | G | G | H | Q | T | I | K | V | D | I | R | I | I | A | A |
Query Conservation |   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |
|   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |
| . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|
|
|
Template Sequence |   |
C | Q | A | M | K | K | I | F | D | D | A | . |
. |
. |
. |
. |
. |
. |
. |
Y | K | S | Q | L | S | C | V | V | V | D | D | I | E | R | L | L | D | Y | V | P | I | G | P | R | F | S | N | L | V | L | Q | A | L | L | V | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | K | A | P | P | Q | G | R | K | L | L | I | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  | T | S | S |  |  |  |  |  |  |
|
|  |  |  |  | T | T |
| B | T | T | T | T | B |
|
|  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | T |
|
|
| S | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
590 | . | . | . | . | . | . | . | . | . | 600 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | 640 | . | . | . | . | . | . | . | . | . | 650 | . |
  |
  |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | N | R | D | L | Q | A | M | V | K | E | G | T | F | R | E | D | L | F | Y | R | L | N | V | I | H | L | I | L | P | P | L | R | D | R | R | E | D | I | S | L | L | A | N | H | F | L | Q | K | F | S | S | E | N | Q | R | D | I | I | D | I | D | P | M | A | M | S | L | L | T | A | W | S | W | P | G | N | I | R | E |
Query Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |   |   |
|   |   |   |   |
|   |   |
|
| . | . | . | . | . |   |   |   |
|   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
G | T | T | S | R | K | D | V | L | Q | E | M | E | M | L | N | A | F | . |
. |
. |
. |
. |
S | T | T | I | H | V | P | N | I | A | T | G | E | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | L | E | A | L | E | L | L | G | N | F | K | D | K | E | R | T | T | I | A | Q | Q | V | K | G | K | K | V | W | I | G | I | K | K |
Template Known Secondary structure |   |
 |  |  | S |
|  |  |  |  |  |  | T | T |
| T | T | T | S | . | . | . | . | . | S |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
652 | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . |
  |
  |   |
365 | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | N | V | I | E | R | A | V | V | M | N | S | G | P | I | I |
Query Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | L | M | L | I | E | M | S | L | Q | M | D | P | E | Y | R | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T | S |
| G | G | G |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
718 | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . |
  |