|   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | |
. | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | K | I | A | L | S | Q | A | S | V | L | I | S | G | E | S | G | T | G | K | E | L | I | A | R | A | I | H | Y | N | S | R | R | A | K | G | P | F | I | K | V | N | C | A | . |
A | L | P | E | S | L | L | E | S | E | L | F | G | H | E | K | G | A | F | T | G | A | Q | T | L | R | Q | G | L | F | E | R | A | N |
Query Conservation |   |
|   |   |   |
|   |   |   |   |
|
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|   | . |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
|
|   |
|
|   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
| . | . | . |
|   |   |
|
|   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |   |
|   |
|
|
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Template Sequence |   |
L | T | D | S | L | H | Q | K | Y | G | G | C | F | F | G | P | A | G | T | G | K | T | E | T | V | K | A | F | . |
. |
. |
G | Q | N | L | G | R | V | V | V | V | F | N | C | D | D | S | F | D | Y | Q | V | L | S | R | L | L | V | G | I | T | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T | T |  |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  | . | . | . | T | S | S |
|
|
|
|
|
|  |  |
|
| S | S | S | S |
| S |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1782 | . | . | . | . | . | . | . | 1790 | . | . | . | . | . | . | . | . | . | 1800 | . | . | . | . | . | . | . | . | . | |
|
|
1810 | . | . | . | . | . | . | . | . | . | 1820 | . | . | . | . | . | . | . | . | . | 1830 | . | . | . | . | . | . | . | . | . | 1840 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
  |
  |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
. | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |  |
|
|  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  | . |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | G | T | L | L | L | D | E | I | G | E | M | P | L | V | L | Q | . |
. |
. |
. |
. |
. |
. |
A | K | L | L | R | I | L | Q | E | R | E | F | E | R | I | G | G | H | Q | T | I | K | V | D | I | R | I | . |
I | A | A | T | N | R | D | L | Q | A | M | V | K | E | G | T | F | R | E | D | L | F | Y | R | L | N | V | I |
Query Conservation |   |
|
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |
| . | . | . | . | . | . | . |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| . |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|
|
|
|
|
|
|
|   |   |   |
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|   |
|
|
|
|
|
Template Sequence |   |
G | A | W | G | C | F | D | E | F | N | R | L | D | E | K | V | L | S | A | V | S | A | N | I | Q | Q | I | Q | N | G | L | Q | V | G | K | S | H | I | T | L | L | E | E | E | T | P | L | S | P | H | T | A | V | F | I | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | P | E | N | L | K | K | S | F | R | E | F |
Template Known Secondary structure |   |
|
|
|
|  |  |
| T | T | T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T | S | S | S |
|
|
|
|
| S | S |
|
|
|
|
|
|
|
|
|
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  | T | T | T |
|  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1842 | . | . | . | . | . | . | . | 1850 | . | . | . | . | . | . | . | . | . | 1860 | . | . | . | . | . | . | . | . | . | 1870 | . | . | . | . | . | . | . | . | . | 1880 | . | . | . | . | . | . | . | . | . | 1890 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | 1900 | . | . | . | . | . | . | . | . | . | 1910 |
  |
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | L | I | L | P | P | L | R | D | R | R | E | D | I | S | L | L | A | N | H | F | L | Q | K | F | S | S | E | N | Q | R | D | I | I | D | I | D | P | M | A | M | S | L | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | W | S | W | P | G | N | I | R | E | L | S | N | V | I | E | R | A | V | V | M | N | S | G | P |
Query Conservation |   |
  |
|   |
|
|   |
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   | . | . | . | . | . | . | . | . | . | . |   |
|   |
|
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . |
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
| . |   |
| . | . | . | . | . | . | . |
|   |   |   |
|   |
|
|   |
|   |
|   |
|
|   |   |
|   | . | . | . |   |
|
|   |
|
|   |   |
|   |   |
|   |   |   |   |
|
|   |
|   |
|
|
|
|
| . | . |
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |
|   |   |
Template Sequence |   |
S | M | . |
K | S | . |
. |
. |
. |
. |
. |
. |
Q | S | G | T | I | A | E | M | I | L | Q | I | M | G | F | E | D | S | K | . |
. |
. |
S | L | A | S | K | I | V | H | F | L | E | L | L | S | S | K | C | S | S | M | N | H | Y | H | F | G | . |
. |
L | R | T | L | K | G | V | L | R | N | C | S | P | L | I | S | E | F |
Template Known Secondary structure |   |
 |
| . |
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S | S |
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S |
Template Predicted Secondary structure |   |
 |  | . |
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1920 | . | |
. | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 1930 | . | . | . | . | . | . | . | . | . | 1940 | . | . | |
|
|
. | . | . | . | . | . | . | 1950 | . | . | . | . | . | . | . | . | . | 1960 | . | . | . | . | . | . | . | . | |
|
. | 1970 | . | . | . | . | . | . | . | . | . | 1980 | . | . | . | . | . | . |
  |
  |   |
380 | . | . | . | . | . | . | . | . | . | 390 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | I | F | S | E | D | L | P | P | Q | I | R | Q |
Query Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |
|
|   |   |
Template Sequence |   |
G | E | G | E | K | T | V | V | E | S | L | K | R |
Template Known Secondary structure |   |
S |
| S | S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1988 | . | 1990 | . | . | . | . | . | . | . | . | . | 2000 |
  |