|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | |
|
|
|
. | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
Q | G | V | I | F | D | L | D | G | V | I | T | D | T | . |
. |
. |
. |
A | H | L | H | F | Q | A | W | Q | Q | I | A | A | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | G | I | S |
Query Conservation |   |
|   |
|
|
|
|   |
|
|
|
|   |
|   | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | L | I | A | I | D | L | D | G | T | L | L | N | S | K | H | Q | V | S | L | E | N | E | N | A | L | R | Q | A | Q | R | D | G | I | E | V | V | V | S | T | G | R | A | H | F | D | V | X | S | I | F | E | P | L | G | I | K | T | W | V | I | S | A | N | G | A | V | I | H | D | P | E | G | R | L | Y | H | H | E | T |
Template Known Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
| S |
| T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  | G | G | G | T |
|
|
|  |  |  |  | G | G | G | T |  |  |  |
| T | T |
|
|  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
36 | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | D | A | Q | F | N | E | S | L | K | G | I | S | R | D | E | S | L | R | R | I | L | Q | H | G | G | K | E | G | D | F | N | S | Q | E | R | A | Q | L | A | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | K | N | L | L | Y | V | H | S | L | R | E | L | T | V | N | A | V | L | P | G | I | R | S | L | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | D | K | K | R | A | Y | D | I | L | S | W | L | E | S | E | N | Y | Y | Y | E | V | F | T | G | S | A | I | Y | T | P | Q | N | G | R | E | L | L | D | V | E | L | D | R | F | R | S | A | N | P | E | A | D | L | S | V | L | K | Q | A | A | E | V | Q | Y | S | Q | S | G | F | A | Y | I | N | S | F | Q | E | L | F |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S | S |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
| S |
| G | G | G | G | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
103 | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | D | L | R | A | Q | Q | I | S | V | G | L | A | S | V | S | L | N | A | P | T | I | L | A | A | L | E | L | R | E | F | F | T | F | C | A | D | A | S | . |
. |
. |
. |
. |
. |
Q | L | K | N | S | K | P | D | P | E | I | F | L | A | A | C | A | G | L | G | V | P | P | Q | A | C | I | G | I | E | D | A | Q | A | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |
|
|
Template Sequence |   |
E | A | D | E | P | I | D | F | Y | N | I | L | G | F | S | F | F | K | E | K | L | E | A | G | W | K | R | Y | E | H | A | E | D | L | T | L | V | S | S | A | E | H | N | F | E | L | S | S | R | K | A | S | K | G | Q | A | L | K | R | L | A | K | Q | L | N | I | P | L | E | E | T | A | A | V | G | D | S | L | N | D |
Template Known Secondary structure |   |
S | S | S | S |
|
|
|  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  |
| S | S | T | T |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| G | G | G |  |  |  |  |  | S | S | G | G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
  |
  |   |
177 | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
|
|
|
|
. | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
I | D | A | I | N | A | S | G | M | R | S | V | G | I | G | A | G | L | T | G | A | Q | L | L | L | P | S | T | E | S | L | T | W | P | R | . |
. |
. |
. |
. |
L | S | A | F | W | Q | N | V |
Query Conservation |   |
|   |
|
|   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
|   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |
|   |   | . |   |
|
|
|   |
| . | . | . | . |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |
Template Sequence |   |
K | S | X | L | E | A | A | G | K | . |
G | V | A | X | G | N | . |
. |
. |
. |
A | R | E | D | I | K | S | I | A | D | A | V | T | L | T | N | D | E | H | G | V | A | H | X | X | K | H | L |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | S |  | . |  |  |  |
| T | T | . | . | . | . |
|
|  |  |  |  |  |  |
| S |  |  |
|
|
| G | G | G | T |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
| . |  |  |  |
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
242 | . | . | . | . | . | . | . | 250 | |
. | . | . | . | . | . | |
|
|
|
. | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
  |