Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	A	G	F	I	A	D	T	A	S	L	P	L	I	V	S	N	L	V	N	I	V	S	A	D	F	F	G	L	S	F	A	Q	Y	A	S	V	M	I	S	V	D	A	A	A	I	A	A	T	L	I	M	L	Y	L	F	F	R	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.
Sequence		V	I	P	A	T	Y
Secondary structure
SS confidence
Disorder			?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2bbj chain B Region: 11 - 61 Aligned: 47 Modelled: 51 Confidence: 39.8% Identity: 11% PDB header:metal transport/membrane protein Chain: B: PDB Molecule:divalent cation transport-related protein; PDBTitle: crystal structure of the cora mg2+ transporter Phyre2 PDB 2iub chain A domain 2 Region: 23 - 61 Aligned: 29 Modelled: 39 Confidence: 23.9% Identity: 21% Fold: Transmembrane helix hairpin Superfamily: Magnesium transport protein CorA, transmembrane region Family: Magnesium transport protein CorA, transmembrane region Phyre2 PDB 3si5 chain Y Region: 29 - 39 Aligned: 11 Modelled: 11 Confidence: 9.4% Identity: 9% PDB header:cell cycle Chain: Y: PDB Molecule:protein casc5; PDBTitle: kinetochore-bubr1 kinase complex Phyre2 PDB 3si5 chain X Region: 26 - 39 Aligned: 14 Modelled: 14 Confidence: 9.2% Identity: 7% PDB header:cell cycle Chain: X: PDB Molecule:protein casc5; PDBTitle: kinetochore-bubr1 kinase complex Phyre2 PDB 3bjx chain B Region: 17 - 27 Aligned: 11 Modelled: 11 Confidence: 6.9% Identity: 9% PDB header:hydrolase Chain: B: PDB Molecule:halocarboxylic acid dehalogenase dehi; PDBTitle: structure of a group i haloacid dehalogenase from2 pseudomonas putida strain pp3 Phyre2 1 c2bbjB_ 2 d2iuba2 3 c3si5Y_ 4 c3si5X_ 5 c3bjxB_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2bbjB_ 39.8 11 PDB header:metal transport/membrane protein Chain: B: PDB Molecule:divalent cation transport-related protein; PDBTitle: crystal structure of the cora mg2+ transporter 2 d2iuba2 23.9 21 Fold:Transmembrane helix hairpin Superfamily:Magnesium transport protein CorA, transmembrane region Family:Magnesium transport protein CorA, transmembrane region 3 c3si5Y_ 9.4 9 PDB header:cell cycle Chain: Y: PDB Molecule:protein casc5; PDBTitle: kinetochore-bubr1 kinase complex 4 c3si5X_ 9.2 7 PDB header:cell cycle Chain: X: PDB Molecule:protein casc5; PDBTitle: kinetochore-bubr1 kinase complex 5 c3bjxB_ 6.9 9 PDB header:hydrolase Chain: B: PDB Molecule:halocarboxylic acid dehalogenase dehi; PDBTitle: structure of a group i haloacid dehalogenase from2 pseudomonas putida strain pp3

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0