|   |
12 | . | . | . | . | . | . | . | |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | |
|
|
|
. | 70 | . | . | . | . | . | |
. | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . |  |  |  |  |  |  |  | . |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
| . |
|
|
|
|
Query Sequence |   |
L | L | K | F | K | E | Q | I | . |
E | F | I | D | S | H | A | D | Y | F | H | I | D | I | M | D | G | H | F | V | P | N | L | T | L | S | P | F | F | V | S | Q | V | K | K | L | . |
. |
. |
. |
. |
. |
A | T | K | P | L | D | C | H | L | M | V | T | R | . |
. |
. |
. |
P | Q | D | Y | I | A | Q | . |
L | A | R | A |
Query Conservation |   |
  |   |   |
|   |   |   |
| . |   |   |   |
|   |
|   |
|   |
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |   |
|   |   |   |
|   |   |
|
|   |   | . | . | . | . | . | . |   |   |   |   |
|
|
|
|
|   |   |   |   | . | . | . | . |
|   |   |   |
|   |   | . |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
|
|   |
|   |   |   |   |
|   |   |
|
|
|
|   | . | . | . |
|
|
| . | . |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|   |
|   |   |
|
Template Sequence |   |
F | N | H | F | C | F | Y | I | I | N | E | T | K | E | Y | A | L | A | Y | K | M | N | F | . |
. |
. |
A | F | Y | . |
. |
L | P | Y | G | S | L | G | V | D | V | L | K | N | V | F | D | Y | L | H | H | L | N | V | P | T | I | L | D | I | K | M | N | D | I | G | N | T | V | K | H | Y | R | K | F | I | F | D | Y | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
| S |  |  |  |  |  | G | . | . | . | G | G | G | . | . | S | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  | . | . | . |  |  |  | . | . |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
114 | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
. | . | . | |
|
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . |
  |
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | A | D | F | I | T | L | H | P | E | T | I | N | G | Q | A | F | R | L | I | . |
D | E | I | R | R | H | D | M | K | V | G | L | I | L | N | P | E | T | P | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | A | M | K | Y | Y | I | H | K | A | D | K | I | T | V | M | T | V | D | P | G | F | A |
Query Conservation |   |
|
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |
| . |   |   |   |
|   |   |
|   |
|   |   |
|   |
|   |
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|
|
|   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
R | S | D | S | C | T | A | N | I | Y | M | G | T | Q | M | L | R | D | I | C | L | D | E | E | C | K | R | Y | Y | S | T | F | V | L | V | K | T | T | N | A | D | S | H | I | F | Q | N | R | L | S | L | D | G | K | E | A | Y | V | V | I | A | E | E | V | Q | K | M | A | K | Q | L | H | L | E | E | N | G | E | F | V |
Template Known Secondary structure |   |
|
| S |  |  |  |  |
|
| T | T |
| S | T | T |  |  |  |  |  | B |
| T | T | S |
|
| B |
|  |  |  |  |  |  |  |
| S | S | T | T | T |  |  |  |  | T | T |
|  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | G | G | G | T |
|
|  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . |
  |
  |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
170 | . | . | . | . | . | . | . | . | . | |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | |
. | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . |  |  |  |  |
|
|
|
|  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | P | F | I | P | E | M | L | D | K | L | A | E | L | K | A | W | R | E | R | E | G | L | E | Y | E | . |
I | E | V | D | G | S | C | N | Q | A | . |
T | Y | E | K | L | M | A | A | G | A | D | V | F | I | . |
V | G | T | S | G | L | F | N | H | A | E | N | I | D | E | A | W | R | I | M | T | A | Q | I | L | A |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |
|   |
|
|
|
|
|   |   |   | . |   |
|   |   |   |   |   |   |
|
|
|   |
|
| . |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|   |
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|
| . | . |   |
|   |
|
|   |   |
|
|   |   |   |   |
|   |
|   |
|
Template Sequence |   |
G | F | V | V | G | A | N | C | Y | D | E | I | K | K | I | R | E | L | F | P | D | C | Y | I | L | A | P | G | V | G | A | Q | K | G | D | L | R | K | M | L | C | N | G | Y | S | K | N | Y | E | K | V | L | I | N | V | G | R | A | I | T | . |
. |
K | S | G | S | P | Q | Q | A | A | R | E | Y | H | Q | Q | I | K | E |
Template Known Secondary structure |   |
 |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |
|
| B | S | T | T |
| B |
|  |  |  |  |  |  |  |  |
|
| S | S | G | G | G |  |  |  |  |  |
|  |  |  |  | . | . | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
269 | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
. | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
  |
  |   |
220 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
A | K | S | E | V |
Query Conservation |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |
Template Sequence |   |
V | L | A | E | L |
Template Known Secondary structure |   |
 |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
  |   |
347 | . | . | 350 | . |
  |