|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | |
|
|
. | . | 60 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | |
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  | . | . | . | . | . |  |  |  |
|
|  | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
K | I | S | P | S | L | M | C | M | D | L | L | K | F | K | E | Q | I | E | F | I | . |
D | S | H | A | D | Y | F | H | I | D | I | M | D | G | H | F | V | P | N | L | T | L | S | P | F | F | V | S | Q | V | K | K | L | A | T | . |
. |
. |
K | P | L | D | C | H | . |
. |
. |
. |
. |
L | M | V | T | R | P | . |
. |
. |
Query Conservation |   |
|
|   |
|
|
|   |
|   |
|   |   |   |
|   |   |   |
|   |   |   | . |
|   |
|   |
|   |
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   | . | . | . |   |   |
|
|
|
| . | . | . | . | . |
|   |   |   |   |
| . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |
|   |   |
|
|
|   |   |   |   |   |
|   |
|
|
|   |   |
|   |
|   |
|
|   |   |   |
|
|   |   | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |
|
Template Sequence |   |
K | E | Y | L | I | N | I | T | G | P | V | N | I | M | E | K | R | A | E | M | V | A | N | E | G | G | Q | Y | V | M | I | D | I | . |
. |
. |
. |
. |
. |
. |
. |
V | V | A | G | W | S | A | L | Q | Y | M | R | E | V | T | E | D | L | G | L | A | I | H | A | H | R | A | M | H | A | A | F | T | R | N | P | R | H | G |
Template Known Secondary structure |   |
|  |  |  |
| B |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
| T | T | T |  |  |  |  | S |
| T | T | S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  | . | . | . | . | . | . | . | . |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
  |
  |   |
|
|
|
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . |
Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
Q | D | Y | I | A | Q | L | A | R | A | G | A | D | F | I | T | L | H | P | E | T | I | N | . |
. |
. |
. |
. |
G | Q | A | F | R | L | I | D | E | I | R | R | H | D | M | K | V | G | L | I | L | N | P | E | T | P | V | E | A | M | K | Y | Y | I | H | K | A | D | K | I | T | V | M | T | V | D | P | G | F |
Query Conservation |   |
. | . | . |   |   |   |
|   |   |   |   |   |
|
|
|
|   |
|   |
|
|   |
|   |   |   | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |   |
|
|   |
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
I | T | M | L | A | L | A | K | A | A | R | M | I | G | V | D | Q | I | H | T | G | T | A | V | G | K | M | A | G | N | Y | E | E | I | K | R | I | N | D | F | L | L | S | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |
|
|
|
|
| S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
293 | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
142 | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | Q | P | F | I | P | E | M | L | D | K | L | A | E | L | K | A | W | R | E | R | E | G | L | E | Y | E | I | E | V | D | G | S | C | N | Q | A | T | Y | E | K | L | M | . |
A | A | G | A | D | V | F | I | V | G | T | S | G | L | F | N | H | A | E | N | I | D | E | A | W | R | I | M | T | A | Q | I | L | A | A |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |   |
|   |   |   |   | . |   |   |
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|
|
|
|   |
|
|
|
|
|   |   |
|
|
|   |
|   |
|
|
|   |
|
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | E | H | I | R | P | V | F | P | V | A | S | G | G | L | H | P | G | L | M | P | E | L | I | R | L | F | G | K | D | L | V | I | Q | A | G | G | G | V | M | G | H | P | D | G | P | R | A | G | A | K | A | L | R | D | A | I | D | A | A |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T |
|
|
|
|  |  |  |  |  | S | S |
|
| G | G | G |  |  |  |  |  |  |  |  |
| S |
|
|  |  |  |
|  |  |  |  |  | T |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
337 | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . |
  |
  |   |
221 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
K | S | E | V | Q |
Query Conservation |   |
  |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
Template Sequence |   |
I | E | G | V | D |
Template Known Secondary structure |   |
 |  | T |
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
  |   |
397 | . | . | 400 | . |
  |