|   |
1 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | I | S | P | S | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | C | M | D | L | L | K | F | K | E | Q | I | E | F | I | D | S | H | A | D | Y | F | H | I | D | I | M | D | G | H | F | V | P | N | L | T | L | S | P | F | F | V | S | Q | V | K | K | L | A | T | K | P | L | D |
Query Conservation |   |
  |
|
|   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |
|   |
|   |
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|   |
|
|
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   | . | . |   |   |   |
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |
|   |   |   |   | . |   |   |   |
|   |   |
|   |   |   |   |   |
|
|
|   |
Template Sequence |   |
L | R | I | I | P | C | L | D | I | D | G | G | A | K | V | V | V | K | G | V | N | F | Q | G | I | R | E | V | G | D | P | V | E | M | A | V | R | Y | . |
. |
E | E | E | G | A | D | E | I | A | I | L | D | I | T | A | A | P | E | G | R | A | T | F | . |
I | D | S | V | K | R | V | A | E | A | V | S | I | P | V | L |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |
| G | G | G |
|  |  |
| T | T |
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | . | . |  |  | T | T |
| S |
|  |  |  |  |  |
|
|
|
| T | T | T |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  | . | . |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
. | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
62 | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 120 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | H | L | M | V | T | R | P | Q | D | Y | I | A | Q | L | A | R | A | G | A | D | F | I | T | L | H | P | E | T | I | N | G | Q | A | F | R | L | I | D | E | I | R | R | H | D | M | K | V | G | L | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | N | P | E | T | P | V | E | A |
Query Conservation |   |
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |   |
|   | . |
|   |   |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | G | G | G | V | R | S | L | E | D | . |
A | T | T | L | F | R | A | G | A | D | K | V | S | V | N | T | A | A | V | R | . |
N | P | Q | L | V | A | L | L | A | R | E | F | G | S | Q | S | T | V | V | A | I | D | A | K | W | N | G | E | Y | Y | E | V | Y | V | K | G | G | R | E | A | T | G | L | D | A | V | K | W |
Template Known Secondary structure |   |
 |  | S | S |
|
| S |  |  |  | . |  |  |  |  |  |  |  | T |
| S |  |  |  |  | S |  |  |  |  |  | . |
| T |  |  |  |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | |
. | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | |
. | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
122 | . | . | . | . | . | . | |
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | Y | Y | I | H | K | . |
A | D | K | I | T | V | M | T | V | D | P | G | F | A | G | Q | P | F | I | P | E | M | L | D | K | L | A | E | L | K | A | W | R | E | R | E | G | L | E | Y | E | I | E | V | D | G | S | C | . |
N | Q | A | T | Y | E | K | L | M | A | A | G | A | D | V | F | I | V | G | T | S | G | L |
Query Conservation |   |
  |   |   |   |   |   |   | . |   |
|   |
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
| . |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . |   |   |   |   |
|
|
|
|   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
| . |
|
Template Sequence |   |
A | K | E | V | E | E | L | G | A | G | E | I | L | L | T | S | I | D | R | D | G | T | G | L | G | Y | D | V | E | L | I | R | R | V | A | D | . |
. |
. |
. |
. |
. |
. |
. |
S | V | R | I | P | V | I | A | S | G | G | A | G | R | V | E | H | F | Y | E | A | A | A | A | G | A | D | A | V | L | A | A | S | L | . |
F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T |
| S |  |  |  |  |  |  | T | T | T | T | T | T |
| S |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |
| S | S |
|  |  |  |  | S |
|
|
| S |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  | S |  |  | . |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | |
230 |
  |
  |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | N | H | A | E | N | I | D | E | A | W | R | I | M | T | A |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
H | F | R | V | L | S | I | A | Q | V | K | R | Y | L | K | E |
Template Known Secondary structure |   |
 | T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
  |