|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
|
|
|
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
70 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
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|
|
|
|
|
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|
|
|
|
|
|
|
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|
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|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
Query Sequence |   |
K | I | S | P | S | L | M | C | M | D | L | L | K | F | K | E | Q | I | E | F | I | . |
D | S | H | A | D | Y | F | H | I | D | I | M | D | G | H | F | V | P | N | L | T | L | S | P | F | F | V | S | Q | V | K | K | . |
. |
. |
. |
L | A | T | K | P | L | D | C | H | L | M | V | T | R | P | . |
. |
. |
. |
. |
. |
Q |
Query Conservation |   |
|
|   |
|
|
|   |
|   |
|   |   |   |
|   |   |   |
|   |   |   | . |
|   |
|   |
|   |
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |   |
|   |   |   |
|   |   |
|
|   | . | . | . | . |   |   |   |   |   |
|
|
|
|
|   |   |   |   |
| . | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
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|
|
| . | . | . | . |
|
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|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
Template Conservation |   |
|
|
|
|
|
| . | . |
|
|
|
|   |
|   |
|   |
|   |   |
|
|   |
|
|   |
|
|   |
|
|
|   |
|
|
|   | . | . | . | . |   |
|   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |
|   |   |
|
|   |
|
|   |
|
|
|
|
|   |
Template Sequence |   |
S | I | I | G | T | I | . |
. |
G | P | K | T | N | N | P | E | T | L | V | A | L | R | K | A | G | L | N | I | V | R | M | N | F | S | H | G | S | . |
. |
. |
. |
Y | E | Y | H | K | S | V | I | D | N | A | R | K | S | E | E | L | Y | P | G | R | P | L | A | I | A | L | D | T | K | G | P | A | L | S | E | K | D | K |
Template Known Secondary structure |   |
 |  |  |  |  |
| . | . |
| T | T | T |
| S |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  | T | T | S |
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S |
|
| B |
|  |  |  |
|
|
|
|
| S |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
  |   |
22 | . | . | . | . | . | |
|
. | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
  |
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | Y | I | A | Q | L | A | R | A | G | A | D | F | I | T | L | H | P | E | T | I | N | G | Q | A | F | R | L | I | D | E | I | R | R | H | D | M | K | V | G | L | I | L | N | P | E | T | P | V | . |
. |
E | A | M | K | Y | Y | I | H | K | A | D | K | I | T | V | M | T | V | D | P | G | F | A | G | Q | P | F | I | P |
Query Conservation |   |
  |   |
|   |   |   |   |   |
|
|
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |
|   |
|   |
|   |
|   |   | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
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|
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|
|
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|
|
|
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|
|
| . | . |
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |   |   |
|
|
|   |
|   |
|
|
|
|   |
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|   |
|
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   | . | . |   |   |
|
Template Sequence |   |
E | D | L | R | F | G | V | K | N | G | V | H | M | V | F | A | S | F | I | R | T | A | N | D | V | L | T | I | R | E | V | L | G | E | Q | G | K | D | V | K | I | I | V | K | I | E | N | Q | Q | G | V | N | N | F | D | E | I | L | K | V | T | D | G | V | M | V | A | R | G | D | L | G | I | E | I | . |
. |
P | A | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |
|
|  |  |
|
| T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | T | T | S |
|
|  |  |  |  |
| S |  |  |  |  | T | T |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  | S | . | . |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |
|
|
| . | . |
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
197 | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
. | . | . |
  |
  |   |
149 | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | M | L | D | K | L | A | E | L | K | A | W | R | E | R | E | G | L | E | Y | E | I | E | V | D | G | S | C | N | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | T | Y | E | K | L | M | A | A | G | A | D | V | F | I | V | G | T | S | G | L | F | N | H | A | E | N | I | D | E | A | W | R | I | M | T | A |
Query Conservation |   |
  |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
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|
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|
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|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|
|   |
|
|   |   |
|   |   |   | . | . |
|
|
|
|
|   |
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|
|   |
|   |
|
|
|
|   |
| . | . |
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |
Template Sequence |   |
E | V | L | A | V | Q | K | K | L | I | A | K | S | N | L | A | . |
. |
G | K | P | V | I | C | A | T | Q | M | L | E | S | M | T | Y | N | P | R | P | T | R | A | E | V | S | D | V | G | N | A | I | L | D | G | A | D | C | V | M | L | S | G | E | . |
. |
T | A | K | G | N | Y | P | I | N | A | V | T | T | M | A | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | T |
|
|  |  |  |  | S | S | S | S | G | G | G | G | T |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |
|
| S |  |  | . | . |  |  | S |
| S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | |
|
. | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 |
  |
  |   |
216 | . | . | . | 220 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | I | L | A | A | K | S | E | V | Q |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |   |   |
Template Sequence |   |
T | A | V | I | A | E | Q | A | I | A |
Template Known Secondary structure |   |
 |  |  |  | T | T | S | S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
  |   |
351 | . | . | . | . | . | . | . | . | 360 |
  |