Job Description P32719 Confidence 97.77% Date Thu Jan 5 11:50:42 GMT 2012 Rank 196 Aligned Residues 178 % Identity 11% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		8	.	10	.	.	.	.	.	.	.	.	.	20	.	.		.	.	.	.	.	.	.	30	.	.	.		.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.
Predicted Secondary structure																	.												.
Query SS confidence																	.												.
Query Sequence		M	C	M	D	L	L	K	F	K	E	Q	I	E	F	I	.	D	S	H	A	D	Y	F	H	I	D	I	.	M	D	G	H	F	V	P	N	L	T	L	S	P	F	F	V	S	Q	V	K	K	L	A	T	K	P	L	D	C	H	L	M	V	T	R	P	Q	D	Y	I	A	Q	L	A	R	A	G	A	D	F	I	T
Query Conservation																	.												.
Alig confidence																	.												.																												.	.	.
Template Conservation																																																									.	.	.
Template Sequence		N	I	V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	.	.	.	P	V	L	T	P	N	L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V
Template Known Secondary structure		S																	T	T		S										T	T	T		G	G	G	T	T								S				T	T		B		.	.	.						S										T	T		S
Template Predicted Secondary structure																																																									.	.	.
Template SS confidence
		49	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.				.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.
		86	.	.	.	90	.	.																.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.									.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.		.	.	.	.	.	.	.	140	.
Predicted Secondary structure									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.																	.
Query SS confidence									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.																	.
Query Sequence		L	H	P	E	T	I	N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	Q	A	F	R	L	I	D	E	I	R	R	H	D	M	K	V	G	L	I	L	N	P	E	.	.	.	.	.	.	.	.	T	P	V	E	A	M	K	Y	Y	I	H	K	A	D	K	I	.	T	V	M	T	V	D	P	G	F
Query Conservation									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.																	.
Alig confidence									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.																	.
Template Conservation
Template Sequence		I	F	G	A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	I	S	L	G	D	T
Template Known Secondary structure						S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S																T	T		S							T
Template Predicted Secondary structure
Template SS confidence
		126	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
		142	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.					.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.
Predicted Secondary structure																																	.	.	.	.
Query SS confidence																																	.	.	.	.
Query Sequence		A	G	Q	P	F	I	P	E	M	L	D	K	L	A	E	L	K	A	W	R	E	R	E	G	L	E	Y	E	I	E	V	.	.	.	.	D	G	S	C	N	Q	A	T	Y	E	K	L	M	A	A	G	A	D	V	F
Query Conservation																																	.	.	.	.
Alig confidence				.	.	.	.																										.	.	.	.
Template Conservation				.	.	.	.
Template Sequence		I	G	.	.	.	.	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V
Template Known Secondary structure		T		.	.	.	.																		S		G	G	G						B		T	T	S												T	T
Template Predicted Secondary structure				.	.	.	.
Template SS confidence
		206	.					.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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