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Job DescriptionP33225
Confidence100.00%DateThu Jan 5 11:51:24 GMT 2012
Rank20Aligned Residues594
% Identity23%Templated1y5ia2
SCOP infoFormate dehydrogenase/DMSO reductase, domains 1-3 Formate dehydrogenase/DMSO reductase, domains 1-3 Formate dehydrogenase/DMSO reductase, domains 1-3
Resolution1.90

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   45....50.........60.........70.........80. ........90.........100......
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Query Sequence  DAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDK. . . . . . . . . . . YPSKMIAGLPDHVHNAARIRYPMVR. . . . . . .
Query Conservation             
   
   
 
 

 



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Template Conservation 
         

   
   
 



 
 
     
 
    
 
    
 
 

 
    

 







 
      
Template Sequence  DKIVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMKMW
Template Known Secondary structure  S


SSSS



TT


S



TTS


TT


TGGGGGTSTTB

S
Template Predicted Secondary structure 


















































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   42.......50.........60.........70.........80.........90.........100.........110.........120.
 
   107..110.........120.........130.........140.........150.........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . VDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASG
Query Conservation  ...........................            
 

 
    







 

 

  
    
  

    
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Template Conservation              
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Template Sequence  REAKALHSDPVEAWASIIEDADKAKSFK. . . . . . . . . . . QARGRGGFVRSSWQEVNELIAASNVYTIKNYGPDRVAGFSP
Template Known Secondary structure  TT
SST
...........TTTTSS


T
GGG

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   122.......130.........140......... 150.........160.........170.........180.........190
 
   160.........170.........180.........190.........200.........210.........220.........230.........
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Query Sequence  WQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQAN
Query Conservation                  
    
                      
             
   

 

  
 

  
    
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Template Sequence  IPAMSMVSYASG. . ARYLSLIGGTCLSFYD. WYCDLPPASPQTWGE. . . . QTDVPESADWYNSSYIIAWGSNVPQTRTPD
Template Known Secondary structure 
GGGS..T


TT.TTT
S
TS
....S




TT
SS

SGGG
Template Predicted Secondary structure 



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   191........200.. .......210........ .220.........230... ......240.........250.........260...
 
   240.........250.........260.........270.........280.........290.........300.........310...
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Query Sequence  WWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDK. . . . . .
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Template Sequence  A. . . . . . . . . . . . HFFTEVRYKGTKTVAVTPDYAEI. . . . AKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFT
Template Known Secondary structure  ............GGGT

SS

....TSS


TT
TTTS

Template Predicted Secondary structure  ............







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   264 .....270.........280....... ..290.........300.........310.........320.......
 
   314.....320..
Predicted Secondary structure 


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Query SS confidence 








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Query Sequence  NFLANYCVG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation   

   
 
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Template Sequence  DYVRRYTDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIGFRWGEKGKWNLEQRDG
Template Known Secondary structure  BSTTB
SSS
BGGGBTTGGG

SSGGG
B
BTTS

BTTSGGGTSSS
S

S
SSBBT
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   328.330.........340.........350.........360.........370.........380.........390.........400.......
 
   323.....
Predicted Secondary structure  ..........................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .





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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FEQFLP. . . . . . . .
Query Conservation  ..................................................................      ........
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Template Sequence  KTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGL
Template Known Secondary structure  TT

B

B



TTS
S

TT


TTS





SBTTS
TTB

SS
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   408.410.........420.........430.........440.........450.........460.........470.........480.......
 
   329330.........340.........350.........360..... ....370.........380.........390........
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Query Sequence  . . . . YLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAAN. . . . . . RTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQI
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Template Sequence  NDVNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCGCV
Template Known Secondary structure 

TTSBSSTTS

TT



TS

TSTTTT
T
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   488.490.........500.........510.........520.........530.........540.........550.........560.......
 
   399400.........410 .........420.........430.........440......
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Query Sequence  GLPGGGFGFGWH. . . . . . . . . YNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYS. . . . . . . . . . . . . . . . . . . . . . .
Query Conservation 
  


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Template Sequence  GQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYTGHLIDFNV
Template Known Secondary structure  TSTT

SS



SSTTTT
S


TTGGGG



SGGGS
TTS
GGGS
S
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   568.570.........580.........590.........600.........610.........620.........630.........640.......
 
   447..450.........460.........470.........480.........490.
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . STIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRH. . . . . . .
Query Conservation  ............................   
           
              

       

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Template Conservation       

 
  
                                               
  

   
 
 
   
  
 
Template Sequence  RAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFM
Template Known Secondary structure  TTSS

SS
BSS
TTSTTS
TSS
BGGG
TTSSSSS

S

TTTTT
SS
Template Predicted Secondary structure 










































































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   648.650.........660.........670.........680.........690.........700.........710.........720.......
 
   492.......500.........510.........520.........530.........540......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . QQINRIIEGLRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRG
Query Conservation  .........................
      


 





  
   



  





 
   
  
           
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Template Sequence  LKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDMNTSDMHP. . F
Template Known Secondary structure  TT
S




S

TTTTT



SSS


SS





SSB

T
SB

TTSS


SSSS..
Template Predicted Secondary structure 







































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   728.730.........740.........750.........760.........770.........780.........790.........800.... .
 
   547..550.........560.........570....
Predicted Secondary structure 












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Query Sequence  IIAMKQVVPPQFEARNDFDIFRELCRRF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation 
      
 
 



 
  
   

 

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Template Sequence  IHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAPHI
Template Known Secondary structure 

SS

STT
B
TTTT




TTSGGG


SSS


GGGTSS


BTTTB
Template Predicted Secondary structure 















































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   806...810.........820.........830.........840.........850.........860.........870.........880.....
 
   575....580.........590....
Predicted Secondary structure  ...................................................










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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NREEAFTEGLDEMGWLKRIW. . . . . . . . .
Query Conservation  ...................................................
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Template Conservation       

          
                       
                            
         
Template Sequence  MVVERDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQ
Template Known Secondary structure  GGGTB

TT
TT


B

SSTTTTSBB

S
TTTB
Template Predicted Secondary structure 













































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   886...890.........900.........910.........920.........930.........940.........950.........960.....
 
   595....600.........610......... 620.........630........ .640.........650....
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Query Sequence  . . . QEGVQQGKGRGVHLPAFDDFWNNKE. . . . . . . . . . . . . . . . YVEFDHPQMFVRHQAFRED. PDLEPLGTPSGLIEIY
Query Conservation  ...                         ................                   .       
 


 
 
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Template Conservation               
     
                        
           
           

 
 


  

Template Sequence  VAVKAWAALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQLY
Template Known Secondary structure  SS

GGGTGGGTT
B

S




TTSSS


SSS


TT



SSTTSSB


Template Predicted Secondary structure 























































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   966...970.........980.........990.........1000.........1010.........1020.........1030.........1040.....
 
   655....660.........670......
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Query Sequence  SKTIADMNYDDCQGHPMWFEKI
Query Conservation 
  
           
    
 
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Template Conservation   
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Template Sequence  QD. . HQWMRDFGESLLVYRPPI
Template Known Secondary structure 

..STT
SS






Template Predicted Secondary structure 
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   1046. ..1050.........1060.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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