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Job DescriptionP33225
Confidence100.00%DateThu Jan 5 11:51:24 GMT 2012
Rank8Aligned Residues726
% Identity20%Templatec1h0hA_
PDB info PDB header:dehydrogenaseChain: A: PDB Molecule:formate dehydrogenase (large subunit); PDBTitle: tungsten containing formate dehydrogenase from2 desulfovibrio gigas
Resolution1.8 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   37..40.........50.........60...... ...70.........80... ......90.........100.........110
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Query Sequence  ATAAQAATDAVISKEGILTGSHWGAIRATV. . KDGRFVAAKPFELDKYP. . . . SKMIAGLPDHVHNAARIRYPMVRVDWL
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Template Sequence  ATMALKTVDAKQTTSVCCYCSVGCGLIVHTDKKTNRAINVEGDPDHPINEGSLCAKGASTWQLAENERRPANPLYRA. . .
Template Known Secondary structure 




TTTTS
SSBTT


TTT


TT
TTTTT


TS
TTS
SS

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   1........10.........20.........30.........40.........50.........60.........70.......
 
   111........120.........130.........140.........150... ......160.........170........
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Query Sequence  RKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSA. . . . . . . . . . . . LLTASGWQSTGMFHNASGMLAKAIA
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Template Sequence  . . . . . . . . P. . GSDQWEEKSWDWMLDTIAERVAKTREATFVTKNAKGQVVNRCDGIASVGSAAMD. . . NEECWIYQAWLR
Template Known Secondary structure  ........T..T
SS



TTS

S

TTS
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   78 .80.........90.........100.........110.........120.........130.. .......140....
 
   179180.........190.........200.........210.........220.........230.........240.........250........
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Query Sequence  LHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKV
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Template Sequence  SLGLFYIEHQARIHSATVAALAESYGR. . . . GAMTNHWIDLKNSDVILMMGSNPAENHPISF. . . . . . . . . . . . KWVMRA
Template Known Secondary structure  TTB


GGG

S
....
S
SS
TGGGGG
SS

STT............
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   145....150.........160.........170. ........180.........190.........200.. ......
 
   259260.........270.........280.........290.........300.........310.........320..
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Query Sequence  AAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVG. . . . . . . . . . . . . . . .
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Template Sequence  KDKGATLIHVDPRYTRT. . . . STKCDLYAPLRSGSDIAFLNGMTKYILEKELYFKDYVVNYTNASFIVGEGFAFEEGLFA
Template Known Secondary structure  TT

SS

TT....GGG
S


TT
TT
S
BGGGBBB
TT

TTT
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   210.........220...... ...230.........240.........250.........260.........270.........280.....
 
   323......330.........340.........350.........360.....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAAN.
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Template Sequence  GYNKETRKYDKSKWGFERDENGNPKRDETLKHPRCVFQIMKKHY. . . . . . ERYDLDKISAICGTPKELILKVYDAYCATG
Template Known Secondary structure  TTTTT
GGGG
B
B
TTS
B
B
TTS
STTB......TT




GGG
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   286...290.........300.........310.........320......... 330.........340.........350.........
 
   366...370.........380.........390.........400.........410.........420.........430.........440.
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Query Sequence  . . . . RTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSD
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Template Conservation         
    
     

    

   
  
 
 

 



     
  
  
    
      
             
Template Sequence  KPDKAGTIMYAMGWTQHTVGVQNIRAMSINQLLLGNIGVAGGGVNALRGEANVQGSTDHGLLMHIYPGYLGTARASIPTY
Template Known Secondary structure  STT





SSTT
SSSTT
S

SBTTTT
BTTTTT

BTT

S
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   360.........370.........380.........390.........400.........410.........420.........430.........
 
   442.......450 .........460.........470.........480.......
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Query Sequence  YKGYSSTIP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNP
Query Conservation          
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Template Conservation                                                                       

       

Template Sequence  EEYTKKFTPVSKDPQSANWWSNFPKYSASYIKSMWPDADLNEAYGYLPKGEDGKDYSWLTLFDDMFQGKIKGFFAWGQNP
Template Known Secondary structure 





TT


GGGG
TTS
S

B
TT


STT


S

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   440.........450.........460.........470.........480.........490.........500.........510.........
 
   488.490.........500.........510.........520. ........530.........540.........550....
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Query Sequence  FHRHQQINRIIEGLRKLETVIAIDNQWTSTCRFA. . . . . . . . . . . . . DIVLPATTQFERNDLDQYGNHSNRGIIAMKQVV
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Template Sequence  ACSGANSNKTREALTKLDWMVNVNIFDNETGSFWRGPDMDPKKIKTEVFFLPCAVAIEKE. . . GSISNSGRWMQWRYVGP
Template Known Secondary structure  SBSTT
SSS

TTTTGGGSTT

GGG


B

GGG

...
TT


SS
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   520.........530.........540.........550.........560.........570......... 580.........590......
 
   555....560.........570.........580.........590.........600.... ....
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Query Sequence  PPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGR. . . . . . . . . . . . . . . . . . . . . . . . . . GVHL
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Template Sequence  EPRKNAIPDGDLIVELAKRVQKLLAKTPGKLAAPVTKLKTDYWVNDHGHFDPHKIAKLINGFALKDFKVGDVEYKAGQQI
Template Known Secondary structure 


TT
B
S
TT

S
GGGGB
TTS
B

BBSS
TT
TT
B
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   597..600.........610.........620.........630.........640.........650.........660.........670......
 
   609610.........620...... ...630.........640...
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Query Sequence  PAFDDFWNNKEYVEFDHP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QMFVRHQAFREDPDLEP. . . . . . .
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Template Conservation           
                                            
                         
Template Sequence  ATFGHLQADGSTTSGCWIYTGSYTEKGNMAARRDKTQTDMQAKIGLYPGWTWAWPVNRRIIYNRASVDLNGKPYAPEKAV
Template Known Secondary structure  S
GGG

TTS
B

SSGGGTTSTTGGG
B




T

TTBSTTTT
SSTTGGGGB
TTS
BS
GGG
S
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   677..680.........690.........700.........710.........720.........730.........740.........750......
 
   644.....650.........660.........670.........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERS. . . . . . . . . . . .
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Template Conservation                                       
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Template Sequence  VEWNAAEKKWVGDVPDGPWPPQADKEKGKRAFIMKPEGYAYLYGPGREDGP. . . . . . LPEYYEPMECPVIEHPFSKTLHN
Template Known Secondary structure  TTTTS

SS
S

TT
TTT


S
TTSSSS
B
SS
TTSTT
S......S






SSS



SS
S

S
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   757..760.........770.........780.........790.........800....... ..810.........820.........830
 
   680.........690.........700... ......710.........720.........730.........740........
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Query Sequence  . . . . . . . . . HGGPGSQKYPLHLQSVHPDFRLHS. . QLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARG
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Template Sequence  PTALHFATEEKAVCDPRYPFICSTYRVTEHWQTGLMTRNTPWLLE. . . AEPQMFCEMSEELATLRGIKNGDKVILESVRG
Template Known Secondary structure  TT

SS

SS




TTS


TT

TTSTS...S
S

T

TT
TT
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   831........840.........850.........860.........870..... ....880.........890.........900.......
 
   749750.........760.........770.. .......780.........790.........800.........810.......
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Query Sequence  QVLAGAVVSDRYAPGVARIHEGAW. YDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEK
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Template Sequence  KLWAKAIITKRIKPFAIQGQQVHMVGIPWHYGWSFPKNGGDAANILTPSV. GNPNTGIPETKAFMVNVTK
Template Known Secondary structure 
TT


TT
S


TTSSTTS


GGGS

BS.SS
SSBSB

S
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   908.910.........920.........930.........940.........950....... ..960.........970......
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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