|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | |
. | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
|
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
M | R | S | A | Q | V | Y | R | W | Q | I | P | M | D | A | G | V | V | L | R | D | R | R | L | K | T | R | D | G | L | Y | V | C | L | . |
R | E | G | E | R | E | G | W | G | E | I | S | P | L | P | . |
. |
G | F | S | Q | E | T | W | E | E | A | Q | S | V | L | L | A | W | V | N | N | W | L | A | G | . |
. |
. |
. |
Query Conservation |   |
|   |   |
|   |
|   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
| . |
|
|   |
|   |   |
|   |
|
|   |
|
|   |
| . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |
Template Sequence |   |
I | E | A | A | E | I | V | V | A | R | L | P | L | K | T | H | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | V | P | L | L | I | L | H | G | E | G | V | Q | G | V | A | E | G | T | M | E | A | R | P | M | Y | R | E | E | T | I | A | G | A | L | D | L | L | R | G | T | F | L | P | A | I | L | G | Q | T | F | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  | B |
|
|  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
|
|
| B | S | S | S | S | S | S | S |
| B |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  | T | T |
|  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
. | . | . | . | . | . | 130 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|
|  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
D | C | E | L | P | Q | M | P | S | V | A | F | G | V | S | C | A | L | A | E | L | T | D | T | L | P | Q | A | A | N | Y | R | A | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | C | N | G | D | P | D | D | L | I | L | K | L | A | D | . |
. |
M | P | G | E | K | V | A | K |
Query Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |
|   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|   |   |
|
|   |   |   |   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
Template Sequence |   |
N | P | E | A | V | S | D | A | L | G | S | Y | R | G | N | R | M | A | R | A | M | V | E | M | A | A | W | D | L | W | A | R | T | L | G | V | P | L | C | T | L | L | G | G | H | K | E | Q | V | E | V | G | V | S | L | G | I | Q | A | D | E | Q | A | T | V | D | L | V | R | R | H | V | E | Q | G | Y | R | R | I | K |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  | T |
| S |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| B |  |  |  |  |  | T |
|
|
| S |  |  |  | B |
|  |  |  |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S |
|  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
  |
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
. | . | . | . | 200 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | K | V | G | L | Y | E | A | V | R | D | G | M | V | V | N | L | L | L | E | A | I | P | D | L | H | L | R | L | D | A | N | R | A | W | T | P | L | K | G | Q | Q | F | A | K | Y | V | N | P | D | Y | R | D | R | I | A | F | L | E | E | P | C | K | T | . |
. |
R | D | D | S | R | A | F | A | R | E | T | G | I | A |
Query Conservation |   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   | . | . | . |   |   |
|   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   | . |   |   |
|   |   |   | . | . | . |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|
Template Sequence |   |
L | K | I | K | P | . |
. |
. |
G | W | D | V | Q | P | V | R | A | T | R | E | A | F | P | D | I | R | L | T | V | D | A | N | S | A | Y | T | L | A | D | A | G | R | L | . |
R | Q | L | D | E | Y | . |
. |
. |
D | L | T | Y | I | E | Q | P | L | A | W | D | D | L | V | D | H | A | E | L | A | R | R | I | R | T | P |
Template Known Secondary structure |   |
 |  |
| B | T | . | . | . | T | B | S |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |
| T | T |
|
|
| G | G | G |  |  |  |  | . |  | G | G | G | G | G | . | . | . |
|
| S |
|  |  |
|
| S |
| T | T |
| S |  |  |  |  |  |  |  |  |  |
| S | S |
|
Template Predicted Secondary structure |   |
 |  |
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
169 | 170 | . | . | . | |
|
|
. | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | |
. | 210 | . | . | . | . | |
|
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
  |
  |   |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | |
|
. | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  | . | . |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | W | D | E | S | L | R | E | P | D | F | A | . |
. |
F | V | A | E | E | G | V | R | A | V | V | I | K | P | T | L | T | G | S | L | E | K | V | R | E | Q | V | Q | A | A | H | A | L | G | L | T | A | V | I | S | S | S | I | E | S | S | L | G | L | T | Q | L | A | R | I | A | A | W | L | T | P | D | T | I | P |
Query Conservation |   |
|
|   |
|
|
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |   |
|
|   |
|
|   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |
Template Sequence |   |
L | C | L | D | E | S | V | A | S | A | S | D | A | R | K | A | L | A | L | G | A | G | G | V | I | N | L | K | V | A | R | V | G | G | H | A | E | S | R | R | V | H | D | V | A | Q | S | F | G | A | P | V | W | C | G | G | M | L | E | S | G | I | G | R | A | H | N | I | H | L | S | C | L | S | N | F | R | L | P | G |
Template Known Secondary structure |   |
 |  |  | S | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  | T | S |
| S |  |  |  |  |
| T | T | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T | S | T | T | B |
| S |
| B |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
  |
  |   |
288 | . | 290 | |
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
|
|
| . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | L | D | . |
T | L | D | L | M | Q | A | Q | Q | V | R | R | W | P | G | S | T | L | P | V | V | E | V | D |
Query Conservation |   |
|
|
| . |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
Template Sequence |   |
D | T | S | S | A | S | R | Y | W | E | R | D | L | I | Q | E | P | L | E | A | V | D | G | L | M | P | V | P |
Template Known Secondary structure |   |
S |
|
|
| G | G | G | T | B | S | S |
| S | B | S | S |
|
|
|
| B | T | T |  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
322 | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
  |