Job Description P12996 Confidence 98.29% Date Thu Jan 5 11:33:15 GMT 2012 Rank 17 Aligned Residues 224 % Identity 12% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		76	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	E	V	E	Q	V	L	E	S	A	R	K	A	K	A	A	G	S	T	R	F	C	M	G	A	A	W	K	N	P	H	E	R	D	M	P	Y	L	E	Q	M	V	Q	G	V	K	A	M	G	L	E	A	C	M	T	L	G	T	L	S	E	S	Q	A	Q	R	L	A	N	A	G	L	D	Y	Y	N	H	N	L	D
Query Conservation
Alig confidence																																																		.
Template Conservation																																																		.
Template Sequence		V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	.	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V	I	F	G	A
Template Known Secondary structure																	T	T		S										T	T	T		G	G	G	T	T								S				.	T	T		B							S										T	T		S
Template Predicted Secondary structure																																																		.
Template SS confidence
		51	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.		.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.
		156	.	.	.	160	.	.	.	.	.	.	.	.	.				170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.							.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.
Predicted Secondary structure																.	.	.																												.	.	.	.	.	.
Query SS confidence																.	.	.																												.	.	.	.	.	.
Query Sequence		T	S	P	E	F	Y	G	N	I	I	T	T	R	T	.	.	.	Y	Q	E	R	L	D	T	L	E	K	V	R	D	A	G	I	K	V	C	S	G	G	I	V	G	L	G	.	.	.	.	.	.	E	T	V	K	D	R	A	G	L	L	L	Q	L	A	N	L	P	T	P	P	E	S	V	P	I	N	M	L	V	K
Query Conservation																.	.	.																												.	.	.	.	.	.
Alig confidence																.	.	.																												.	.	.	.	.	.																			.	.					.	.	.	.	.	.
Template Conservation																																																																						.	.					.	.	.	.	.	.
Template Sequence		A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	.	.	Y	E	I	S	.	.	.	.	.	.
Template Known Secondary structure		S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S																T	T		.	.	S				.	.	.	.	.	.
Template Predicted Secondary structure																																																																						.	.					.	.	.	.	.	.
Template SS confidence
		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.			.	.	200	.
		227	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.		.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.									.	.	.	.	.	.
Predicted Secondary structure																																											.																									.	.	.	.	.	.	.	.
Query SS confidence																																											.																									.	.	.	.	.	.	.	.
Query Sequence		V	K	G	T	P	L	A	D	N	D	D	V	D	A	F	D	F	I	R	T	I	A	V	A	R	I	M	M	P	T	S	Y	V	R	L	S	A	G	R	E	Q	.	M	N	E	Q	T	Q	A	M	C	F	M	A	G	A	N	S	I	F	Y	G	C	K	L	L	.	.	.	.	.	.	.	.	T	T	P	N	P	E
Query Conservation																																											.																									.	.	.	.	.	.	.	.
Alig confidence						.	.	.	.																																		.																									.	.	.	.	.	.	.	.
Template Conservation						.	.	.	.
Template Sequence		L	G	D	T	.	.	.	.	I	G	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V	D	S	S	V	A	G	L	G	G	C	P	Y	A	Q	G	A	S	G	N	L	A
Template Known Secondary structure					T	.	.	.	.	T																			S		G	G	G						B		T	T	S												T	T							B	T	T	S					T	T	S	S	S				B		B
Template Predicted Secondary structure						.	.	.	.
Template SS confidence
		202	.	.	.					.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
		298	.	300	.	.	.	.	.	.	.	.	.	310	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	D	K	D	L	Q	L	F	R	K	L	G	L	N	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	E	D	L	V	Y	M	L	E	G	L	G	I	H	T
Template Known Secondary structure												T	T		B
Template Predicted Secondary structure
Template SS confidence
		278	.	280	.	.	.	.	.	.	.	.	.	290	.	.

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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