|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | |
|
. | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
M | K | Q | V | C | V | L | G | N | G | Q | L | G | R | M | L | R | Q | A | G | E | P | L | G | . |
. |
I | A | V | W | P | V | G | L | D | A | E | P | A | A | V | P | F | Q | Q | S | V | I | T | A | E | I | E | R | W | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|   |
|
|
|
|
|   |
|   |   |   |
|   |
|
|   |
|
|   |   |   |
| . | . |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |
|
|
|
|   |   |   |
|   |   |   | . |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |
|
|   |
|
|
|   |   |
|   |
Template Sequence |   |
K | P | H | L | L | I | T | S | A | G | R | R | A | . |
K | L | V | E | Y | F | V | K | E | F | K | T | G | R | V | S | T | A | D | C | S | P | L | A | S | A | L | Y | X | A | D | Q | H | Y | I | V | P | K | I | D | E | V | E | Y | I | D | H | L | L | T | L | C | Q | D | E | G | V | T | A | L | L | T | L | I | D | P |
Template Known Secondary structure |   |
|
|  |  |  |  |  | S |
| T | T |
|  | . |  |  |  |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  | S |
| T | T |
| G | G | G | G | G | S | S | S |  |  |  |
|
|
| T | T | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | S | S |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | |
. | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
|
|
|
|
|
|
|
55 | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
E | T | A | L | T | R | E | L | A | R | H | P | A | F | V | N | R | D | V | F | P | I | I | A | D | R | L | T | Q | K | Q | L | F | D | K | L | H | L | P | T | A | P | W | Q | L | L | A | E | R | S | E | W | P | A | V | F | D | R | L | G | E | L | A | I | V | K | R | R | T | G | G | Y | D |
Query Conservation |   |
. | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
| . | . | . | . | . | . |
Template Sequence |   |
E | L | G | L | L | A | Q | A | T | E | R | F | Q | A | I | G | V | T | V | I | V | S | P | Y | A | A | C | E | L | C | F | D | K | Y | T | X | Y | E | Y | C | L | R | Q | G | I | A | H | A | R | T | Y | A | T | X | A | S | F | E | E | A | L | A | A | G | E | V | Q | L | P | V | F | V | K | P | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T |  |  |  |  |  | T | T | T |
|  |  |
|
|
|
|  |  |  |  |  |  |  |  | B |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  | S | S |  |  |  |  |  |  |  |  |  | T | T | S | S |
| S |
|  |  |  |  |  | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
| . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | |
|
|
|
|
|
  |
  |   |
128 | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | R | G | Q | W | R | L | R | A | N | E | T | E | Q | L | P | A | E | C | Y | G | E | C | I | V | E | Q | G | I | N | F | S | G | E | V | S | L | V | G | A | R | G | F | D | G | S | T | V | F | Y | P | L | T | H | N | L | H | Q | D | G | I | L | R | T | S | V | A | F | P | Q | A | N | A | Q | Q | Q | A | Q | A | E |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|
|
|   |
|   |
|   | . |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |
|
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | N | G | D | L | I | V | Q | E | L | L | V | G | Q | . |
E | L | G | V | D | A | Y | V | D | L | I | S | G | K | V | T | S | I | F | I | K | E | K | L | T | X | R | A | G | E | T | D | K | S | R | S | V | L | R | . |
. |
. |
. |
D | D | V | F |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | B |
|
|  |  |  |  |  |
|
|
| S |  | . |  |  |  |  |  |  |  |  |
| T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
| . | . | . | . |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | |
|
|
|
. | 210 | . | . |
  |
  |   |
208 | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | M | L | S | A | I | M | Q | E | L | G | Y | V | G | V | M | A | M | E | C | F | V | T | P | Q | G | L | L | I | N | E | L | A | P | R | V | H | N | S | G | H | W | T | Q | N | G | A | S | I | S | Q | F | E | L | H | L | R | A | I | T | D | L | P | L | P | Q | P | V | V | N | N |
Query Conservation |   |
  |   |   |   |
|
|   |   |
|
|
|   |   |
|   |   |   |
|
|
|   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |   |   |   |   | . |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | L | V | E | H | V | L | D | G | S | G | L | V | G | P | L | D | F | D | L | F | D | V | A | G | T | L | Y | L | S | E | I | N | P | R | F | G | G | G | Y | P | H | A | Y | . |
E | C | G | V | N | F | P | A | Q | L | Y | R | N | L | X | H | E | I | N | V | P | Q | I | G | Q | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | S | S |
|
| T | T |  |  |  |  |  | . |  | T | T |
|
|  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
| T | T |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
  |