|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 30 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | N | E | L | R | Q | F | Y | P | L | D | E | L | L | R | A | A | . |
. |
. |
. |
. |
. |
. |
E | I | P | R | S | T | F | Y | Y | H | L | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | L | S | K | P | D | K | Y | A | D | V | K | K | R | I | S | E | I | Y | H | E | N | R | G | R | Y | G | Y | R | R |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
| . | . | . | . | . | . | . |
|
|
|
|
|
|   |
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|   |   |   |   |   | . | . |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
Template Sequence |   |
L | I | F | C | F | H | L | K | K | T | A | A | E | S | H | R | M | L | V | E | A | F | G | E | Q | V | P | T | V | K | T | C | E | R | W | F | Q | R | F | K | S | G | D | F | D | V | D | D | K | E | H | G | K | P | P | K | R | Y | E | D | . |
. |
A | E | L | Q | A | L | L | D | E | D | D | A | Q | T | Q | K | Q | L |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  | T |
| S |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S | S |
|
|
|
|
|
|
|
|
| S | S |
|  | . | . |  |  |  |  |  |  |  |  |  | S | S |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
15 | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | |
|
. | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
  |
  |   |
63 | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | |
|
|
|
. | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | T | L | S | L | H | R | E | G | K | Q | I | N | H | K | A | V | Q | R | L | M | G | T | L | S | L | K | A | A | I | K | V | K | R | Y | R | S | Y | R | G | E | V | G | Q | T | A | P | N | V | L | Q | R | D | . |
. |
. |
. |
F | K | A | T | R | P | N | E | K | W | V | T | D | V | T | E | F | A | V | N | G | R | K |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |
|   |   |
|   |
|
|   |
|
|
|   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
A | E | Q | L | E | V | S | Q | Q | A | V | S | N | R | L | R | E | M | G | K | I | Q | K | V | G | R | W | V | P | H | E | L | N | E | R | Q | M | E | R | R | K | N | T | C | E | I | L | L | S | R | Y | K | R | K | S | F | L | H | R | I | V | T | G | D | E | K | W | I | F | F | V | N | P | K |
Template Known Secondary structure |   |
. | . | . | . | . | . |  | T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
|
|
| S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| G | G | G | G |  |  |  |  |  |  |
|
|  |  | S | B |
|
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
139 | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | Y | L | S | P | V | I | D | L | F | N | N | E | V | I | S | Y | S | L | S | E | R | P | V | M | N | M | V | E | N | M | L | D | Q | A | F | K | K | L | N | . |
. |
. |
. |
. |
P | H | E | H | P | V | L | H | S | D | Q | G |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
Template Sequence |   |
R | K | K | S | Y | V | D | P | G | Q | P | A | T | S | T | A | R | P | N | R | F | G | K | K | T | M | L | C | V | W | W | D | Q | S | G | V | I | Y | Y | E | L | L | K | P | G | E | T | V | N | A | A | R | Y | Q | Q | Q | L | I | N | L | N | R | A | L | Q | R | K | R | P | E | Y | R | V | I | F | L | H | D | N | A |
Template Known Secondary structure |   |
|
|
|
|
|
| S | S | S |
|
|
|
|
|
|
|
|
|
| S | S |
|
|  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
| S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|
|
|
|  |  |  |
|
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
167 | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
  |
  |   |
191 | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | Q | Y | R | M | R | R | Y | Q | N | I | L | K | E | H | G | I | K | Q | S | M | S | R | K | G | N | C | L | D | N | A | V | V | E | . |
C | F | F | G | T | L | K | S | E | C | F | Y | L | D | E | F | S | N | I | S | E | L | K | D | A | V | T | E | Y | I | E |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |
|
| . |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |
|
|
|
|
|
|
|
| . |
|
|
|   |   |   |
|   |   |
|
|   | . |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | S | H | T | A | R | A | V | R | D | T | L | E | T | L | N | W | E | V | L | P | H | A | A | Y | S | P | D | L | A | . |
P | S | D | Y | H | L | F | A | S | M | G | H | . |
A | L | A | E | Q | R | F | D | S | Y | E | S | V | K | K | W | L | D | E | W | F | A |
Template Known Secondary structure |   |
S | T | T | S |
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |
|
|
|
| T | T |
| T | T | S |
| . |  |  |  |  | T |  |  |  |  |  |  |  | . |  | T | T | T |
| B |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
. | . | . | . | . | . | . | . | 290 | . | . | . | |
. | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . |
  |