|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | I | N | C | A | F | I | G | F | G | K | S | T | T | R | Y | H | L | P | Y | V | . |
L | N | R | K | D | S | W | H | V | A | H | I | F | R | R | H | A | K | P | E | E | Q | A | P | I | Y | S | H | I | . |
H | F | T | S | D | L | D | E | V | L | N | D | P | D | V | K | L | V | V | V | C | T | H | A | D | S | H | F |
Query Conservation |   |
  |
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |
|   |   |   |
| . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|   |
|   |   |   |   |   | . |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |
|
|   |
|   |
|   |
|
|   |   |   |
|   |
Template Sequence |   |
T | L | K | A | G | I | V | G | I | G | X | I | G | S | D | . |
H | L | R | R | L | A | N | T | V | S | G | V | E | V | V | A | V | C | D | I | V | A | G | R | A | Q | A | A | L | D | K | Y | A | I | E | A | K | D | Y | N | D | Y | H | D | L | I | N | D | K | D | V | E | V | V | I | I | T | A | S | N | E | A | H | A |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
|
| S |  |  |  |  |  | . |  |  |  |  |  |  |  | T |
| T | T |  |  |  |  |  |  |  |
| S | S | T | T |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  | S | S |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |
| S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | |
. | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
. | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Y | A | K | R | A | L | E | A | G | K | N | V | L | V | E | K | P | F | T | P | T | L | A | Q | A | K | E | L | F | A | L | A | K | S | K | G | L | T | . |
V | T | P | Y | Q | N | R | R | F | D | S | C | F | L | T | A | K | K | A | I | E | S | G | K | L | G | E | I | V | E | V | E | S | H | F | D | Y | Y | R | P |
Query Conservation |   |
  |   |   |   |   |
|
|   |   |
|
|   |
|   |   |
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   | . |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|
|   |   |
|
|
|
|
|   |
|
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   | . | . | . | . |
Template Sequence |   |
D | V | A | V | A | A | L | N | A | N | K | Y | V | F | C | E | K | P | L | A | V | T | A | A | D | C | Q | R | V | I | E | A | E | Q | K | N | G | K | R | X | V | Q | I | G | F | X | R | R | Y | D | K | G | Y | V | Q | L | K | N | I | I | D | S | G | E | I | G | Q | P | L | X | V | H | G | R | H | Y | . |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
| S | S | S |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|  |  |  |
|
| G | G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S |  |  |  |  |  |  |  |  |  | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | |
|
|
|
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
. | 190 | . | . | . | . | . | . | |
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
. | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | |
. | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Query Sequence |   |
V | A | E | T | K | P | G | L | P | Q | D | G | A | F | Y | G | L | G | V | H | T | M | D | Q | I | I | S | L | F | G | . |
R | P | D | H | V | A | Y | D | . |
I | R | S | L | R | N | K | A | N | P | D | D | T | F | E | A | Q | L | F | Y | . |
G | D | L | K | A | I | V | K | T | S | H | L | V | K | I | D | . |
Y | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |
|   |
| . |   |   |   |   |
|   |
|   | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | A | S | T | V | P | E | Y | K | T | P | Q | A | I | Y | E | T | L | I | H | E | I | D | V | X | H | W | L | L | N | E | D | Y | K | T | V | K | V | Y | F | P | R | Q | S | S | L | V | T | T | L | R | D | P | Q | L | V | V | X | E | T | T | S | G | I | N | I | V | V | E | V | F | V | N | C | Q | Y | G | Y | D | I |
Template Known Secondary structure |   |
| S |
|
|
| T | T |
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |
|
| S |
|
| T | T |
|
| S | S |
|
| S |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  | T | T |
| S | S |
|
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
157 | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
  |
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | F | I | V | H | G | K | K | G | S | F | I | K | Y | G | I | D | Q | Q | E | T | S | L | K | A | N | I | M | P | G | E | P | G | F | A | A | D | D | S | V | G | V | L | E | Y | V | N | D | E | G | V | T | V | R | E | E | M | K | P | E | M | G | D | Y | G | R | V | Y | D | A | L | Y | Q | T | I | T | H | G | A | P |
Query Conservation |   |
  |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
Template Sequence |   |
H | C | D | V | T | G | E | K | G | X | A | E | L | P | T | V | A | S | A | A | V | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | A | A | K | Y | S | T | D | I | L | V | D | W | K | Q | R | F | I | D | A | Y | D | I | E | F | Q | D | F | F | D | R | L | N | A | G | L | P |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | S |
|  |  |  |
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | T | T |  |  |  |  |
|
|
|
|
| G | G | G | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . |
  |
  |   |
315 | . | . | |
. | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | |
. | . | . | . | . |
Predicted Secondary structure |   |
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |  |  |  |  |
|
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
N | Y | V | . |
K | E | S | E | V | L | T | N | L | E | I | L | E | R | G | F | E | Q | A | S | P | S | T | . |
V | T | L | A | K |
Query Conservation |   |
  |   |   | . |   |   |
|
|
|
|   |   |   |   |
|
|
|
|   |   |   |
|
|   |   |
|   | . |
|   |   |   |   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |
Template Sequence |   |
P | A | G | P | T | S | W | D | G | Y | L | A | A | V | T | A | D | A | C | V | K | S | Q | E | T | G | N | T | E | I | V | E | L |
Template Known Secondary structure |   |
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . |
  |