|   |
138 | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
170 | . | . | |
|
|
|
. | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
| . | . | . | . | . | . |
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | R | V | R | H | T | L | A | Q | A | L | H | R | F | F | N | E | Q | G | F | F | W | V | S | T | P | L | I | T | A | S | D | . |
. |
. |
. |
. |
. |
T | E | G | . |
. |
. |
. |
A | G | E | M | F | R | V | S | T | L | D | L | E | N | L | P | R | N | D | Q | G | K | V | D | F | D | K | D | F | F | G | K | E | S | F |
Query Conservation |   |
|
|   |
|
|   |
|   |   |   |
|
|   |
|
|   |   |   |
|
|   |
|
|   |
|
|   |
|   |   |   |   | . | . | . | . | . | . |   |
|
| . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|   |
Template Sequence |   |
V | K | S | L | R | Q | I | E | G | R | L | R | K | L | F | S | L | K | N | Y | Q | E | V | M | P | P | S | F | E | Y | T | Q | L | Y | T | A | L | E | S | N | G | K | T | F | N | Q | E | K | M | F | Q | F | I | K | H | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | S | I | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|
|
| T | T | S |
|
|  |  |  |
| T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 80 |
  |
  |   |
208 | . | |
|
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
|
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | |
|
|
|
|
Predicted Secondary structure |   |
 |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
Query SS confidence |   |
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
L | T | . |
. |
V | S | G | Q | L | N | G | E | T | Y | A | C | A | L | S | . |
. |
. |
K | I | Y | T | F | G | P | T | F | R | A | E | N | S | N | T | S | R | H | L | A | E | F | W | M | L | E | P | E | V | A | F | A | N | L | N | D | I | A | G | L | A | E | A | M | L | K | Y | V | F | K | A | V | . |
. |
. |
. |
. |
Query Conservation |   |
|   | . | . |   |
|
|
|
|   |
|   |   |
|   |   |
|   |   | . | . | . |
|
|
|   |
|   |   |   |
|
|   |
|   |   |   |
|   |
|
|
|   |
|
|
|   |
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |
| . | . | . | . | . |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
|
|
|
|   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|
|   |   | . | . | . | . | . | . | . | . |
|
|   |   |
|   |
|   |
|
|
|
|   |   |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
Template Sequence |   |
L | R | Y | D | F | T | L | P | L | V | R | L | Y | S | Q | I | K | D | S | T | S | A | R | Y | S | Y | F | G | K | I | F | R | K | E | . |
. |
. |
. |
. |
. |
. |
. |
K | E | N | Y | Q | I | G | I | E | L | F | G | E | S | A | D | K | S | E | L | E | I | L | S | L | A | L | Q | V | I | E | Q | L | G | L | N | K | T |
Template Known Secondary structure |   |
 |
|
|
| S |  |  |  |  |  |  |  |  |  | T |
|
| S |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
278 | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | E | E | R | A | D | D | M | K | F | F | A | E | R | V | D | K | D | A | V | S | R | L | E | R | F | I | E | A | D | F | A | Q | V | D | Y | T | D | A | V | T | I | L | E | N | C | G | R | K | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | N | P | V | Y | W | G |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | F | E | I | G | S | A | K | F | F | Q | R | L | C | Q | L | A | D | G | S | T | E | L | L | T | E | L | L | L | K | K | D | L | S | G | L | N | A | F | I | E | K | N | N | F | S | . |
. |
. |
K | E | L | R | G | L | L | K | E | I | F | I | T | N | E | L | S | R | L | E | N | L | V | T | N | T | K | D | D | V | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  | T | T | S |
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
. | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
  |
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | |
|
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | L | S | S | E | H | E | R | Y | L | A | E | E | H | F | K | A | P | V | V | V | K | N | Y | P | K | D | I | K | A | F | Y | M | R | L | N | E | D | G | K | T | V | A | A | M | D | V | L | A | P | G | I | G | E | . |
. |
I | I | G | G | S | Q | R | E | E | R | L | D | V | L | D | E | R | M | L | E | M | G | L |
Query Conservation |   |
  |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
| . | . |
|   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . | . |
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |   |   |
|
|
|
|   |
|
|
|   |   |   |   |   |   | . |   |   |   |
|
|   |
|
| . | . | . | . |
|
|
|   |
|
|   |   |
|   |   |   | . | . |
Template Sequence |   |
I | S | S | F | D | Q | L | K | E | F | S | E | K | L | S | M | I | K | P | I | I | I | . |
. |
. |
. |
. |
. |
. |
. |
D | L | G | M | V | P | K | M | D | Y | Y | T | D | L | M | F | K | A | Y | S | S | A | A | . |
N | Q | P | I | L | S | G | G | . |
. |
. |
. |
R | Y | D | Q | L | L | S | N | F | Q | E | E | . |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
|
|  |  | . | . | . | . | . | . | . | . |
| T | T |
|
|
| S | S | T | T |
|
| S |  |  |  |  |  |  |  | T | T |  | . |  |  |  |  |  |  |  |  | . | . | . | . |  |
|  |  |  |  |  | T | S | S | S |
| . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
. | . | . | . | . | . | . | . | |
|
|
|
290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
  |
  |   |
413 | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | K | E | D | Y | W | W | Y | R | D | L | R | R | Y | G | T | V | P | H | S | G | F | G | L | G | F | E | R | L | I | A | Y | V |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |
|
|
|   |
|   |
|
|
|
|
|
|
|
|
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|   |
|   |
|
|   |
|   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | F | A | I | G | F | C | C | H | M | D | T | I | L | K | A | L |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
302 | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
  |