|   |
107 | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | T | Y | P | M | A | A | K | R | H | S | I | E | Y | L | R | E | V | A | H | L | R | P | R | T | N | L | I | G | A | V | A | R | V | R | H | T | L | A | Q | A | L | H | R | F | F | N | E | Q | G | F | F | W | V | S | T | P | L | I | T | A | S | D | T | E | G | A | G | E | M | F | R | V | S | T | L | D | L | E | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |
|
|   |
|
|   |   |   |
|
|   |
|
|   |
|
|   |
|   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
|
|   |   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |
|
|   |
|
|   |
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
Template Sequence |   |
L | P | L | D | S | N | H | V | N | . |
T | E | E | A | R | L | K | Y | R | Y | L | D | L | R | R | P | E | M | A | Q | R | L | K | T | R | A | K | I | T | S | L | V | R | R | F | M | D | D | H | G | F | L | D | I | E | T | P | M | L | T | K | A | T | P | E | G | A | R | D | Y | L | V | P | S | R | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
| S | S |
| T | T | S |
|
| . |
|  |  |  |  |  |  | T |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|
|
| S | S | B |
|
|
| S | S | S | S |
|
|
|  |  |  |
| S | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
108 | . | 110 | . | . | . | . | . | . | |
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | |
|
|
|
|
  |
  |   |
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | P | R | N | D | Q | G | K | V | D | F | D | K | D | F | F | G | K | E | S | F | L | T | V | S | G | Q | L | N | G | E | . |
T | Y | A | C | A | L | S | K | I | Y | T | F | G | P | T | F | R | A | E | N | S | N | T | S | R | H | L | A | E | F | W | M | L | E | P | E | V | A | F | A | N | L | N | D | I | A | G | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|
|
|
|   |
|   | . |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |
|
|   |
|   |   |   |
|   |
|
|
|   |
|
|
|   |
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|
|   |   |
|   |   |   |   |   |
|
|
|   |
|
|
|   |
|
|   |
|   |   |   |   |   | . |
|   |   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | H | K | G | K | F | Y | A | L | P | Q | S | P | Q | L | F | K | Q | L | L | M | M | S | G | F | D | R | Y | Y | Q | I | V | K | C | F | R | D | E | D | L | R | A | D | . |
R | Q | P | E | F | T | Q | I | D | V | E | T | S | F | M | T | A | P | Q | V | R | E | V |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | S | S | T | T |
|  |  |  |
|
| S |
| S |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| B | T | T | . | B |
| S |  |  |  |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
182 | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
  |
  |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | |
|
. | . | . | . | 340 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | A | M | L | K | Y | V | F | K | A | V | L | E | E | R | A | D | D | M | K | F | F | A | E | R | V | D | K | D | A | V | S | R | L | E | R | F | I | E | A | D | F | A | Q | V | D | Y | T | D | A | V | T | I | L | E | N | C | G | R | K | F | E | N | P | V | Y | W | G | V | . |
. |
D | L | S | S | E | H | E | R |
Query Conservation |   |
  |
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | E | A | L | V | R | H | L | W | L | E | V | K | G | V | D | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | D | F | P | V | M | T | F | A | E | A | E | R | R | Y | G | S | D | K | P | D | L | R | D | E | S | K | W | A | P | L | W | V | I | D | F | P | M | F | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  | S |
| S | S |
|
|
|
|
|
| S |
|
|
|  |  |  |  |  |
|
| B | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . |
  |
  |   |
344 | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | |
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
Query Sequence |   |
Y | L | A | E | E | H | F | K | A | P | V | V | V | K | N | Y | P | K | D | I | K | A | F | Y | M | R | L | N | E | D | G | K | T | V | A | A | M | D | V | L | A | P | G | I | G | E | I | I | G | G | S | Q | R | E | E | R | L | D | V | L | D | E | R | M | L | E | M | G | L | N | K | E | D | . |
. |
. |
. |
Y | W | W |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   | . |
|
|   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
D | D | G | E | G | G | L | T | A | M | H | H | P | F | T | S | P | K | D | M | T | A | A | E | L | K | A | A | P | E | N | A | V | A | N | A | Y | D | M | V | I | N | G | Y | . |
E | V | G | G | G | S | V | R | I | H | N | G | D | M | Q | Q | T | V | F | G | I | L | G | I | N | E | E | E | Q | R | E | K | F | G | F |
Template Known Secondary structure |   |
 |
| S | S | S |
|  |  |  | S | S |
| T | T | B |
| B | S | S |
|
|  |  |  |  |  |  | S |
| T | T |
| B | B | S |  |  |  |  |  |  | T | T |  | . |  |  |  |  |  |  |  | B |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  | . |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
438 | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | |
. | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . |
  |
  |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | R | D | L | R | R | Y | G | T | V | P | H | S | G | F | G | L | G | F | E | R | L | I | A | Y | V | T | G | V | Q | N | V | R | D | V | I | P | F | P | R | T | P | R | N | A | S |
Query Conservation |   |
|
|   |
|   |   |   |
|   |
|
|
|   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |
|   |
|
|   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |
|
|
|
|   |   |
|
|
|   |   |   |   |   |   |
Template Sequence |   |
L | L | D | A | L | K | Y | G | T | P | P | H | A | G | L | A | F | G | L | D | R | L | T | M | L | L | T | G | T | D | N | I | R | D | V | I | A | F | P | K | T | T | A | A | A | C |
Template Known Secondary structure |   |
 |  |  |  | T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
| G | G | G | G | S | S | S |
|
|
| T | T | S |
| B |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
517 | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . |
  |