Job Description P17109 Confidence 100.00% Date Thu Jan 5 11:35:57 GMT 2012 Rank 23 Aligned Residues 513 % Identity 13% Template c2w93A_ PDB info PDB header:lyase Chain: A: PDB Molecule:pyruvate decarboxylase isozyme 1; PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate3 pyruvamide Resolution 1.60 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	W	A	A	V	I	L	E	A	L	T	R	H	G	V	R	H	I	C	I	A	P	G	S	R	S	T	P	L	T	L	A	A	A	E	N	S	A	F	I	H	H	T	H	F	D	E	R	G	L	G	H	L	A	L	G	L	A	K	V	S	K	Q	P	V	A	V	I	V	T	S	G	T	A	V	A	N	L	Y	P
Query Conservation
Alig confidence																																																																	.
Template Conservation																																																																	.
Template Sequence		T	L	G	K	Y	L	F	E	R	L	K	Q	V	N	V	N	T	V	F	G	L	P	G	D	F	N	L	S	L	L	D	K	I	Y	E	V	E	G	M	R	W	A	G	N	A	N	E	L	N	A	A	Y	A	A	D	G	Y	A	R	I	K	G	M	.	S	C	I	I	T	T	F	G	V	G	E	L	S	A	L	N
Template Known Secondary structure														T	T										G	G	G						G	G	G	G	S	T	T							S																	S		.							T	T
Template Predicted Secondary structure																																																																	.
Template SS confidence
		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.		.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.
		89	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.									120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
Predicted Secondary structure																																	.	.	.	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.	.	.	.
Query Sequence		A	L	I	E	A	G	L	T	G	E	K	L	I	L	L	T	A	D	R	P	P	E	L	I	D	C	G	A	N	Q	A	.	.	.	.	.	.	.	.	I	R	Q	P	G	M	F	A	S	H	P	T	H	S	I	S	L	P	R	P	T	Q	D	I	P	A	R	W	L	V	S	T	I	D	H	A	L	G	T	L	H
Query Conservation																																	.	.	.	.	.	.	.	.
Alig confidence																																	.	.	.	.	.	.	.	.																											.	.	.
Template Conservation																																																																			.	.	.
Template Sequence		G	I	A	G	S	Y	A	E	H	V	G	V	L	H	V	V	G	V	P	S	I	S	S	Q	A	K	Q	L	L	L	H	H	T	L	G	N	G	D	F	T	V	F	H	R	M	S	A	N	I	S	E	T	T	A	M	I	T	D	I	A	T	A	P	A	E	.	.	.	I	D	R	C	I	R	T	T	Y	V	T	Q
Template Known Secondary structure									T	T																	T	T				T	T	S		S	S	S		S	S								T	T		S								T	T	T					.	.	.												T
Template Predicted Secondary structure																																																																			.	.	.
Template SS confidence
		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.				.	150	.	.	.	.	.	.	.	.	.	160
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.			.	.	.	.	.	.	.
Predicted Secondary structure																																																																									.	.
Query SS confidence																																																																									.	.
Query Sequence		A	G	G	V	H	I	N	C	P	F	A	E	P	L	Y	G	E	M	D	D	T	G	L	S	W	Q	Q	R	L	G	D	W	W	Q	D	D	K	P	W	L	R	E	A	P	R	L	E	S	E	K	Q	R	D	W	F	F	W	R	Q	K	R	G	V	V	V	A	G	R	M	S	A	.	.	E	E	G	K	K	V	A
Query Conservation																																																																									.	.
Alig confidence		.																	.	.	.	.	.	.	.																																																.	.
Template Conservation		.																	.	.	.	.	.	.	.
Template Sequence		.	R	P	V	Y	L	G	L	P	A	N	L	V	D	L	N	V	.	.	.	.	.	.	.	P	A	K	L	L	Q	T	P	I	D	M	S	L	K	P	N	D	A	E	S	E	K	E	V	I	D	T	I	L	A	L	V	K	D	A	K	N	P	V	I	L	A	D	A	C	C	S	R	H	D	V	K	A	E	T	K
Template Known Secondary structure		.	S								T	T	G	G	G	S			.	.	.	.	.	.	.		G	G	G	G	G	S					S																								S	S												T	T
Template Predicted Secondary structure		.																	.	.	.	.	.	.	.
Template SS confidence
			161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.								.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.							.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
Predicted Secondary structure																												.	.	.	.	.	.
Query SS confidence																												.	.	.	.	.	.
Query Sequence		L	W	A	Q	T	L	G	W	P	L	I	G	D	V	L	S	Q	T	G	Q	P	L	P	C	A	D	.	.	.	.	.	.	L	W	L	G	N	A	K	A	T	S	E	L	Q	Q	A	Q	I	V	V	Q	L	G	S	S	L	T	G	K	R	L	L	Q	W	Q	A	S	C	E	P	E	E	Y	W	I	V	D	D	I
Query Conservation																												.	.	.	.	.	.
Alig confidence																												.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	L	I	D	L	T	Q	F	P	A	F	V	T	P	M	G	K	G	S	I	D	E	Q	H	P	R	Y	G	G	V	Y	V	G	T	L	S	K	P	E	V	K	E	A	V	E	S	A	D	L	I	L	S	V	G	A	L	T	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	I	V	E	F	H	S	D
Template Known Secondary structure															T	T	T	T	T	S	S		T	T	S	T	T							G	G	G	S										T		S						S					.	.	.	.	.	.	.	.	.	.	.	.	.	.							S	S
Template Predicted Secondary structure																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290															.	.	.	.	.	.	.	.
		313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	G	R	L	D	P	A	H	H	R	G	R	R	L	I	A	N	I	A	D	W	L	E	L	H	P	A	E	K	R	Q	P	W	C	V	E	I	P	R	L	A	E	Q	A	M	Q	A	V	I	A	R	R	D	A	F	G	E	A	Q	L	A	H	R	I	C	D	Y	L	P	E	Q	G	Q	L	F	V	G	N	S	L
Query Conservation
Alig confidence																																			.	.
Template Conservation																																			.	.
Template Sequence		H	M	K	I	R	N	A	T	F	P	G	V	Q	M	K	F	V	L	Q	K	L	L	T	N	I	A	D	A	A	K	G	Y	K	.	.	P	V	A	V	P	A	R	T	P	A	N	A	A	V	P	A	S	T	P	L	K	Q	E	W	M	W	N	Q	L	G	N	F	L	Q	E	G	D	V	V	I	A	E	T	G	T
Template Known Secondary structure						T	T					T																		T	T	T			.	.																T	T		B										G	G	G	T			T	T							T	T
Template Predicted Secondary structure																																			.	.
Template SS confidence
		313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.			.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.						.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.
Predicted Secondary structure																																									.	.	.	.	.
Query SS confidence																																									.	.	.	.	.
Query Sequence		V	V	R	L	I	D	A	L	S	Q	L	P	A	G	Y	P	V	Y	S	N	R	G	A	S	G	I	D	G	L	L	S	T	A	A	G	V	Q	R	A	.	.	.	.	.	S	G	K	P	T	L	A	I	V	G	D	L	S	A	L	Y	D	L	N	A	L	A	L	L	R	Q	V	S	A	P	L	V	L	I	V	V
Query Conservation																																									.	.	.	.	.
Alig confidence											.																														.	.	.	.	.
Template Conservation											.
Template Sequence		S	A	F	G	I	N	Q	T	T	.	F	P	N	N	T	Y	G	I	S	Q	V	L	W	G	S	I	G	F	T	T	G	A	T	L	G	A	A	F	A	A	E	E	I	D	P	K	K	R	V	I	L	F	I	G	D	G	S	L	Q	L	T	V	Q	E	I	S	T	M	I	R	W	G	L	K	P	Y	L	F	V	L
Template Known Secondary structure						G	G	G	S		.			S	S							T	T	T			T	T																		T	T																T	T								T	T
Template Predicted Secondary structure											.
Template SS confidence
		391	.	.	.	.	.	.	.	.		400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
		468	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.				510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.			.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.
Predicted Secondary structure																																												.	.	.																	.	.
Query SS confidence																																												.	.	.																	.	.
Query Sequence		N	N	N	G	G	Q	I	F	S	L	L	P	T	P	Q	S	E	R	E	R	F	Y	L	M	P	Q	N	V	H	F	E	H	A	A	A	M	F	E	L	K	Y	H	.	.	.	R	P	Q	N	W	Q	E	L	E	T	A	F	A	D	A	W	.	.	R	T	P	T	T	T	V	I	E	M	V	V	N	D	T	D	G
Query Conservation																																												.	.	.																	.	.
Alig confidence																				.	.	.	.																					.	.	.																	.	.
Template Conservation																				.	.	.	.
Template Sequence		N	N	D	G	Y	T	I	Q	K	L	I	H	G	P	K	A	Q	Y	.	.	.	.	N	E	I	Q	G	W	D	H	L	S	L	L	P	T	F	G	A	K	D	Y	E	T	H	R	V	A	T	T	G	E	W	D	K	L	T	Q	D	K	S	F	N	D	N	S	K	I	R	M	I	E	V	M	L	P	V	F	D	A
Template Known Secondary structure			S	S	S						T	T	S		T	T		G	G	.	.	.	.	G							G	G	G					T	T		S	S								B									T		T	T	T	T	S			S										T	T
Template Predicted Secondary structure																				.	.	.	.
Template SS confidence
		470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.					.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.
		543	.	.	.	.	.	.	550	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	Q	T	L	Q	Q	L	L	A	Q	V	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	Q	N	L	V	E	Q	A	K	L	T	A
Template Known Secondary structure													S
Template Predicted Secondary structure
Template SS confidence
		546	.	.	.	550	.	.	.	.	.	.	.