|   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
|
|
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | |
|
. | . | . | 90 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
| . | . |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | E | Q | K | T | L | H | I | Y | N | W | S | D | Y | I | A | . |
. |
. |
. |
. |
P | D | T | V | A | N | F | E | K | E | T | G | I | K | V | V | Y | D | V | F | . |
. |
. |
D | S | N | E | V | L | E | G | K | L | M | A | G | S | T | G | F | D | L | V | V | P | S | A | . |
. |
S | F | L | E | R | Q | L | T | A |
Query Conservation |   |
  |
|   |   |   |
|
|   |
|   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | E | K | P | L | T | L | K | I | H | M | H | F | R | D | K | W | V | W | D | E | N | W | P | V | A | R | E | V | A | R | L | T | N | V | K | L | V | G | V | A | N | R | A | A | T | N | S | Q | E | Q | F | N | L | M | M | A | S | G | Q | L | P | D | I | V | G | G | D | N | L | K | D | K | F | I | R | Y | G | M | E |
Template Known Secondary structure |   |
| S | S |
|  |  |  |  |  |  |  |  |  | T | T | T |  |  |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  |  |
| S |
| S | S |
| S |
|  |  |  |  |  |  |  |  |  | T | S | S | S |
|
| S |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . |
  |
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | F | Q | P | L | D | K | S | K | L | P | E | . |
. |
. |
. |
. |
. |
W | K | N | L | D | P | E | L | L | K | L | V | A | K | H | D | P | D | N | K | F | A | M | P | Y | . |
. |
. |
M | W | A | T | T | G | I | G | Y | N | V | D | K | V | K | A | V | L | G | E | N | A | P | V | D | S | W | D | L | I | L | K | P |
Query Conservation |   |
|   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |
|   | . | . |   |   |
|   |
|   |   |
|   |   |   |   |
Template Sequence |   |
G | A | F | I | P | L | N | K | L | I | D | Q | N | A | P | N | L | K | A | F | F | K | T | H | P | E | V | Q | R | A | I | T | A | . |
P | D | G | N | I | Y | Y | L | P | Y | V | P | D | G | L | V | S | R | G | Y | F | I | R | Q | D | W | L | D | K | L | H | L | . |
. |
K | T | P | Q | T | V | D | E | L | Y | T | V |
Template Known Secondary structure |   |
T | S | B |
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  | B |
| . | T | T | S |
| B |
|
|  |  |  |  |
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . |
|
|
|
| B |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | |
|
. | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
167 | . | . | 170 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
|
|
|
|
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
E | N | L | E | K | L | K | S | C | . |
. |
. |
. |
. |
. |
. |
G | V | S | F | L | D | A | P | E | E | V | F | A | T | V | L | N | Y | L | G | K | D | P | N | S | T | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | D | D | Y | T | G | P | A | T | D | L | L | L | K | L | R | . |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
L | K | A | F | K | E | K | D | P | N | G | N | G | K | A | D | E | I | P | F | I | N | R | D | P | E | E | V | F | R | L | V | N | F | W | G | A | R | S | T | G | S | N | T | W | M | D | F | Y | V | E | N | G | K | I | K | H | P | F | A | E | V | A | F | K | D | G | I | K | H | V | A | Q | W | Y | K | E | G | L | I |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
| T | T |
| S | S | S |
|
|
|  |  |  |
|
| S |
| T |  |  |  |  |  | G | G | G | G | G | T |
|
| S |
| S | S | S | S | T | T |
|
|  |  |  | T | T |  |  |  |
| G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | B |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
  |
  |   |
|
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 280 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |
|  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
P | N | I | R | Y | F | H | S | S | Q | Y | I | N | D | L | A | N | G | D | I | C | V | A | I | G | W | A | G | D | V | W | Q | A | S | N | R | A | K | E | A | K | N | G | V | N | V | S | F | S | I | P | K | E | G | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | A | F | F | D | V | F | A | M | P | A | D | A |
Query Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Template Sequence |   |
D | P | E | I | F | T | R | K | A | R | S | R | E | Q | T | F | G | N | N | I | G | G | M | T | H | D | W | F | A | S | T | A | L | F | N | D | A | L | S | K | N | I | P | G | F | K | L | V | P | M | A | P | P | I | N | S | K | G | Q | R | W | E | E | D | A | R | Q | I | P | R | P | D | G | W | A | I | T | A | T | N |
Template Known Secondary structure |   |
| T | T | T | T | T | S | G | G | G |  |  |  |  |  | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | T | S | T | T |
|
|  |  |  |  |
|
|
| B |
| T | T | S |
| B |
| B |
|
|
|
|
| S | S |
| S |
|  |  |  |  | B | T | T |
|
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
  |
  |   |
287 | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | N | K | D | E | A | Y | Q | F | L | N | Y | L | L | R | P | D | V | V | A | H | I | S |
Query Conservation |   |
  |   |   |
|   |
|   |   |
|
|   |   |
|   |
|   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
K | N | P | V | E | T | I | K | L | F | D | F | Y | F | G | P | K | G | R | E | L | S | N |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
324 | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
  |