|   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | F | A | A | A | E | Y | A | V | V | L | K | T | . |
. |
. |
. |
. |
L | S | N | P | F | W | V | D | M | K | K | G | I | E | D | E | A | K | T | L | G | V | S | V | D | I | F | A | S | P | S | E | G | D | F | Q | S | Q | L | Q | L | F | E | D | L | S | N | K | N | Y | K | G | I | A | F | A | P | L | S | S | V | N |
Query Conservation |   |
|   |   |   |   |   |
|
|
|
|   |   |   | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   | . |
Template Sequence |   |
T | N | Q | T | Y | K | I | G | L | V | L | K | G | S | E | E | P | I | R | L | N | P | F | Y | I | N | V | L | L | G | I | S | E | T | C | N | Q | H | G | Y | G | T | Q | T | T | . |
. |
V | S | N | N | M | N | D | L | M | D | E | V | Y | K | M | I | K | Q | R | M | V | D | A | F | I | L | L | Y | S | K | E | N | . |
Template Known Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
| S |
|
| S |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
| . | . |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  | S |
|
|
| T | T | . |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
56 | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | |
|
. | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
  |
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | M | P | V | A | R | A | W | K | K | G | I | Y | L | V | N | L | D | E | K | I | D | M | D | N | L | K | K | A | G | G | N | V | E | A | F | V | T | T | D | N | V | A | V | G | A | K | G | A | S | F | I | I | D | K | L | G | A | E | G | G | E | V | A | I | I | E | G | K | A | G | N | A | S | G | E | A | R | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
. |
D | P | I | K | Q | M | L | I | D | E | S | M | P | F | I | V | I | G | K | P | . |
. |
. |
. |
. |
. |
T | S | D | I | D | H | Q | F | T | H | I | D | N | D | N | I | L | A | S | E | N | L | T | R | H | V | I | E | . |
. |
. |
Q | G | V | D | E | L | I | F | I | T | E | K | G | N | F | E | V | S | K | D | R | I |
Template Known Secondary structure |   |
. |
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  | S |
|
| . | . | . | . | . | . |
| S | S | G | G | G | S | S |
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | T |
|
| S |  |  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
133 | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | |
|
|
. | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
  |
  |   |
176 | . | . | . | 180 | . | . | . | . | . | |
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | G | A | T | E | A | F | K | K | A | . |
S | Q | I | K | L | V | A | S | Q | P | A | D | W | D | R | I | K | A | L | D | V | A | T | N | V | L | Q | R | N | P | N | I | K | A | I | Y | C | A | N | D | T | M | A | M | G | V | A | Q | A | V | A | N | A | G | . |
. |
K | T | G | K | V | L | V | V | G | T | D | G | I |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
| . | . |   |
|   |
|
|   |
|
|
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |
|   |
|   |
|   |   |
Template Sequence |   |
Q | G | F | E | T | V | A | S | Q | F | N | L | D | Y | Q | I | I | E | T | S | N | E | R | E | V | I | L | N | Y | M | Q | N | L | H | T | R | L | K | D | P | N | I | K | Q | A | I | I | S | L | D | A | M | L | H | L | A | I | L | S | V | L | Y | E | L | N | I | E | I | P | K | D | V | M | T | A | T | F | N | D | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T | T |  |  |  |  |  |  | S |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
  |
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | E | A | R | K | M | V | E | A | G | Q | M | T | A | T | V | A | Q | N | P | A | D | I | G | A | T | G | L | K | L | M | V | D | A | E | K | S | G | K | V | I | P | L | D | K | A | P | E | F | K | L | V | D | S | I | L | V | T | Q |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   | . | . | . |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   | . | . |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|
Template Sequence |   |
Y | L | T | E | I | A | S | P | P | . |
. |
. |
Q | T | C | I | D | I | K | P | R | M | L | G | Q | Q | A | G | S | A | I | L | N | I | L | K | N | D | V | . |
. |
I | E | L | V | I | I | D | T | E | L | K | I | R | K | S | T | Q | R |
Template Known Secondary structure |   |
 |  |  |  | T | S | S | S |
| . | . | . |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |  |
|
|  |  |  |
|
| G | G | G |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
283 | . | . | . | . | . | . | 290 | . | |
|
|
. | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
|
. | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
  |