|   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | F | A | A | A | E | Y | A | V | V | L | K | T | L | S | N | P | F | W | V | D | M | K | K | G | I | E | D | E | A | K | T | L | G | V | S | V | D | I | F | A | S | P | S | E | G | D | F | Q | S | Q | L | Q | L | F | E | D | L | S | N | K | N | Y | K | G | I | A | F | A | P | L | S | S | V | N | L | V | M | P | V |
Query Conservation |   |
|   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |
Template Sequence |   |
R | R | Q | T | N | I | I | G | V | Y | L | A | D | Y | G | G | S | F | Y | G | E | L | L | E | G | I | K | K | G | L | A | L | F | D | Y | E | M | I | V | C | S | G | K | K | S | H | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
F | I | P | E | K | M | V | D | G | A | I | I | L | D | W | T | F | P | . |
. |
T | K | E | I |
Template Known Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
| S | S |
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  | S | T | T | T | T | T | . | . | . | . | . | . | . | . | . |
|
|
| T | T | T |
| S |  |  |  |  |  |
| T | T | S |
| . | . |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
56 | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | |
|
. | . | . | . |
  |
  |   |
101 | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | R | A | W | K | K | G | I | Y | L | V | N | L | D | E | K | I | D | M | D | N | L | K | K | A | G | G | N | V | E | A | F | V | T | T | D | N | V | A | V | G | A | K | G | A | S | F | I | I | D | K | L | G | A | E | G | G | E | V | A | I | I | E | G | K | A | G | N | A | S | G | E | A | R | R | N | G | A | T | E |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
Template Sequence |   |
E | K | F | A | E | R | G | H | S | I | V | V | L | D | R | T | T | E | H | R | N | . |
. |
. |
. |
. |
. |
. |
. |
I | R | Q | V | L | L | D | N | R | G | G | A | T | Q | A | I | E | Q | F | V | N | . |
. |
. |
V | G | S | K | K | V | L | L | L | S | G | P | E | K | G | Y | D | S | Q | E | R | L | A | V | S | T | R |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|  |  |  |  | S | S | S |
|
|
| S | T | T | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | T | T |
| S |
|  |  |  |  |  |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . |
  |
  |   |
181 | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | F | K | K | A | S | Q | I | K | L | V | A | S | Q | P | A | D | W | D | R | I | K | A | L | D | V | A | T | N | V | L | Q | R | N | P | N | I | K | A | I | Y | C | A | N | D | T | M | A | M | G | V | A | Q | A | V | A | N | A | G | . |
. |
K | T | G | K | V | L | V | V | G | T | D | G | I | P | E | A | R | K | M |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
| . | . |   |
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
E | L | T | R | F | . |
G | I | P | Y | E | I | I | Q | G | D | F | T | E | P | S | G | Y | A | A | A | K | K | I | L | S | Q | P | Q | T | E | P | V | D | V | F | A | F | N | D | E | M | A | I | G | V | Y | K | Y | V | A | E | T | N | Y | Q | M | G | K | D | I | R | I | I | G | F | D | N | S | E | L | G | A | F | V |
Template Known Secondary structure |   |
 |  |  |  | T | . | T |
|
|  |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
| S | S |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
|
| B | T | T | T |  |  |  |  |
| S | S |
|
|  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |
| . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
194 | . | . | . | . | |
. | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
  |
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | E | A | G | Q | M | T | A | T | V | A | Q | N | P | A | D | I | G | A | T | G | L | K | L | M | V | D | A | E | K | S | G | K | V | I | P | L | D | K | A | P | E | F | K | L | V | D | S | I | L | V | T |
Query Conservation |   |
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |
Alig confidence |   |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   | . | . | . |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |
| . | . |   |   |   |
|
|   |
|   |
|   |   |
Template Sequence |   |
Q | P | R | . |
. |
. |
L | A | T | I | A | Y | S | K | H | R | W | G | M | V | A | A | E | K | I | I | H | L | M | R | G | E | A | A | E | S | E | H | I | . |
. |
Y | T | R | F | I | E | G | E | S | F | P |
Template Known Secondary structure |   |
S | S |
| . | . | . |
| B |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  | . | . |
|
|  |  |  |
|
| T | T | S |
|
Template Predicted Secondary structure |   |
|
|
| . | . | . |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  | . | . |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
273 | . | . | |
|
|
. | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | |
|
. | 310 | . | . | . | . | . | . | . | . | . |
  |