|   |
128 | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | P | L | A | S | A | S | I | A | Q | V | H | T | A | R | L | K | . |
. |
. |
. |
. |
S | N | G | K | E | V | V | I | K | V | I | R | P | D | I | L | P | V | I | K | A | D | L | K | L | I | Y | R | L | A | R | W | V | P | R | L | L | P | D | G | R | R | L | R | P | T | E | V | V | R | E | Y | E | K | T | L | I | D |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   | . | . | . | . | . |   |   |
|   |   |
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |
|
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |   | . | . | . | . | . |
Template Sequence |   |
R | E | L | G | Q | G | S | F | G | M | V | Y | E | G | V | A | K | G | V | V | K | D | E | P | E | T | R | V | A | I | K | T | V | N | E | A | A | S | M | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | R | I | E | F | L | N | E | A | S | V | M | K | E | F | N | C | H | H | V | V | R | L | L | G | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S |
|  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
|
| T | T | B |
|
|  |  |  | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
973 | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | |
|
|
|
|
  |
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | N | L | L | R | E | S | A | N | A | I | Q | L | R | R | N | F | E | D | S | P | M | L | Y | I | P | E | V | Y | P | D | Y | C | S | E | G | M | M | V | M | E | R | I | Y | G | I | P | V | S | D | V | A | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | E | K | N | G | T | N | M | K | L | L | A | E | R | G | V | Q |
Query Conservation |   |
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | V | S | Q | G | Q | P | T | L | V | I | M | E | L | M | T | R | G | D | L | K | S | Y | L | R | S | L | R | P | A | M | A | N | N | P | V | L | A | P | P | S | L | S | K | M | I | Q | M | A | G | E |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
| S | S | S | S |
|  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1038 | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . |
  |
  |   |
274 | |
|
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
Predicted Secondary structure |   |
 | . | . |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | . |
. |
F | F | T | Q | V | F | R | D | S | F | F | H | A | D | M | H | P | G | N | I | F | V | S | Y | E | H | P | E | N | P | K | Y | I | G | I | D | C | G | I | V | G | S | L | N | K | E | D | K | R | Y | L | A | E | N | F | I | A | F | F | N | R | D | Y | R | K | V | A | E | L | H | V | D | S | G | W | V | P |
Query Conservation |   |
  | . | . |   |
|   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . |   |   |   |   |
Template Sequence |   |
I | A | D | G | M | A | Y | L | N | A | N | K | F | V | H | R | D | L | A | A | R | N | C | M | V | A | . |
. |
. |
. |
E | D | F | T | V | K | I | G | D | F | G | M | T | R | D | I | Y | E | T | D | Y | Y | R | K | G | G | K | G | L | L | P | V | R | W | M | S | P | E | S | L | K | D | . |
. |
. |
. |
G | V | F | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |
|
| S | G | G | G |  |  |  |
| . | . | . | . | T | T |
|
|  |  |  |
|
| T | T |
|
|
| G | G | G | G | G | G |
|  |  | G | G | G | S | S |  |  |
| G | G | G |
|
|  |  |  |  |  |  | . | . | . | . |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1089 | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | |
|
|
|
. | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | |
|
|
|
. | . | . | 1160 |
  |
  |   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | |
. | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | D | T | N | V | E | E | F | E | F | A | I | R | T | V | C | E | P | I | F | E | K | P | L | A | E | I | S | F | G | H | V | L | L | N | L | F | N | T | A | R | R | F | N | M | E | . |
V | Q | P | Q | L | V | L | L | Q | K | T | L | L | Y | V | E | G | V | G | R |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |
|   |   |   |   |   |
|   |
|   |
|   |   |
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|   |
|   |
|
|
|
|
|   |
| . |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
Template Sequence |   |
T | Y | S | D | V | W | S | F | G | V | V | L | W | E | I | A | T | . |
L | A | E | Q | P | Y | Q | G | L | S | N | E | Q | V | L | R | F | V | M | E | G | G | L | L | D | K | P | D | N | C | P | D | M | L | F | E | L | M | R | M | C | W | Q | Y | N | P | K | M | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | S |
|
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1161 | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | |
. | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . |
  |