|   |
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | S | A | S | I | A | Q | V | H | T | A | R | L | K | S | . |
. |
. |
. |
. |
N | G | K | E | V | V | I | K | V | I | R | P | D | I | L | P | V | I | K | A | D | L | K | L | I | Y | R | L | A | R | W | V | P | R | L | L | P | D | G | R | R | L | R | P | T | E | V | V | R | E | Y | E | K | T | L | I | D | E | L |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   | . | . | . | . | . |   |
|   |   |
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   | . | . | . | . | . | . | . |
Template Sequence |   |
L | G | E | D | R | F | G | K | V | Y | K | G | H | L | F | G | P | A | P | G | E | Q | T | Q | A | V | A | I | K | T | L | K | D | K | A | E | G | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | R | E | E | F | R | H | E | A | M | L | R | A | R | L | Q | H | P | N | V | V | C | L | L | G | . |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |
| S | S | S |  |  |  |  |  |  |  |
|
| S | S | T | T | S |
|
|  |  |  |  |  |  |  |  |
| T | T |
|
|  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
479 | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | |
|
|
|
|
|
|
  |
  |   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
. | . | . | . | . | . | . | . | 280 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | L | L | R | E | S | A | N | A | I | Q | L | R | R | N | F | E | D | S | P | M | L | Y | I | P | E | V | Y | P | D | Y | C | S | E | G | M | M | V | M | E | R | I | Y | G | I | P | V | S | D | V | A | A | L | E | K | N | G | T | N | M | K | L | L | A | E | R | G | . |
V | Q | V | F | F | T | Q | V | F | R | D | S |
Query Conservation |   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . |   |   |   |   |
|   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | V | T | K | D | Q | P | L | S | M | I | F | S | Y | C | S | H | G | D | L | H | E | F | L | V | M | R | S | A | L | E | P | P | D | F | V | H | L | V | A | Q | I | A | A | G | M | E | Y | L | S | S | H | H |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
| S | S | S | S |  |  |  |  |  |  |
|
| S | S |
| B |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
542 | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . |
  |
  |   |
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | F | H | A | D | M | H | P | G | N | I | F | V | S | Y | E | H | P | E | N | P | K | Y | I | G | I | D | C | G | I | V | G | S | L | N | K | E | D | K | R | Y | L | A | E | N | F | I | A | F | F | N | R | D | Y | R | K | V | A | E | L | H | V | D | S | G | W | V | P | P | D | T | N | V | E | E | F | E | F | A | I |
Query Conservation |   |
  |   |
|
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|
Template Sequence |   |
V | V | H | K | D | L | A | T | R | N | V | L | V | Y | . |
. |
. |
. |
D | K | L | N | V | K | I | S | D | L | G | L | F | R | E | V | Y | A | A | D | Y | Y | K | L | L | . |
. |
. |
. |
G | N | S | L | L | P | I | R | W | M | A | P | E | A | I | M | Y | G | K | F | S | I | D | S | D | I | W | S | Y | G | V | V | L |
Template Known Secondary structure |   |
|
|
| S |
|
| S | G | G | G |  |  |  |
| . | . | . | . | G | G | G |
|  |  |  |
|
|
|
|
|
| T | T | T | S | G | G | G | S |  |  |  | T | . | . | . | . | T | T |  |  |  |
| G | G | G |
|
|  |  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
611 | . | . | . | . | . | . | . | . | 620 | . | . | . | . | |
|
|
|
. | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | |
|
|
|
650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . |
  |
  |   |
364 | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | |
. | . | . | . | 430 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | T | V | C | E | P | I | F | E | K | P | L | A | E | I | S | F | G | H | V | L | L | N | L | F | N | T | A | R | R | F | N | M | E | V | Q | P | Q | L | V | L | L | Q | K | T | L | L | Y | V | E | G | V | G | R | Q | L | Y | P | Q | L | D | L | . |
W | K | T | A | K | P | F | L | E | S | W |
Query Conservation |   |
  |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |   |
|
|
|   |   |   |   |
|
|
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   | . | . | . |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |
|   |
Template Sequence |   |
W | E | V | F | S | Y | . |
G | L | Q | P | Y | C | G | Y | S | N | Q | D | V | V | E | M | I | R | N | . |
. |
. |
R | Q | V | L | P | C | P | D | D | C | P | A | W | V | Y | A | L | M | I | E | . |
. |
. |
C | W | N | E | F | P | S | R | R | P | R | F | K | D | I | H | S | R | L | R | A | W |
Template Known Secondary structure |   |
 |  |  |  | T | T | . | T |
|
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  | T | . | . | . | T |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  | . | . | . |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
683 | . | . | . | . | . | |
. | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | |
|
|
. | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | |
|
|
. | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . |
  |