Job Description P0A6A0 Confidence 99.78% Date Thu Jan 5 11:02:40 GMT 2012 Rank 118 Aligned Residues 252 % Identity 14% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

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		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.					.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.
Predicted Secondary structure																			.	.	.	.
Query SS confidence																			.	.	.	.
Query Sequence		K	P	L	A	S	A	S	I	A	Q	V	H	T	A	R	L	K	.	.	.	.	S	N	G	K	E	V	V	I	K	V	I	R	P	D	I	L	P	V	I	K	A	D	L	K	L	I	Y	R	L	A	R	W	V	P	R	L	L	P	D	G	R	R	L	R	P	T	E	V	V	R	E	Y	E	K	T	L	I	D	E
Query Conservation																			.	.	.	.
Alig confidence																			.	.	.	.																			.	.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.	.	.
Template Conservation																																									.	.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.	.	.
Template Sequence		R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	.	.	.	.	.	.	.	.	.	.	H	R	S	G	W	K	Q	E	I	D	I	L	R	T	L	Y	H	E	H	I	I	K	.	.	.	.	.	.	.	.	.
Template Known Secondary structure								S	S										T	T	S	S	S												S	S					.	.	.	.	.	.	.	.	.	.																		T	T	B			.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																									.	.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.	.	.
Template SS confidence
		901	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.											940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	N	L	L	R	E	S	A	N	A	I	Q	L	R	R	N	F	E	D	S	P	M	L	Y	I	P	E	V	Y	P	D	Y	C	S	E	G	M	M	V	M	E	R	I	Y	G	I	P	V	S	D	V	A	A	L	E	K	N	G	T	N	M	K	L	L	A	E	R	G	V	Q	V	F	F	T	Q	V	F	R	D	S
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	K	G	C	C	E	D	A	G	A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	H	S	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.								T	T	T	T										T	T		B					G	G	G	S																								T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																									962	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.
		284	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	F	H	A	D	M	H	P	G	N	I	F	V	S	Y	E	H	P	E	N	P	K	Y	I	G	I	D	C	G	I	V	G	S	L	N	K	E	D	K	R	Y	L	A	E	N	F	I	A	F	F	N	R	D	Y	R	K	V	A	E	L	H	V	D	S	G	W	V	P	P	D	T	N	V	E	E	F	E	F	A	I
Query Conservation
Alig confidence																.	.	.	.																											.	.	.	.	.	.	.
Template Conservation																.	.	.	.																											.	.	.	.	.	.	.
Template Sequence		Y	I	H	R	D	L	A	A	R	N	V	L	L	D	.	.	.	.	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	R	V	G	D	.	.	.	.	.	.	.	S	P	V	F	W	Y	A	P	E	C	L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L
Template Known Secondary structure					S			S	G	G	G					.	.	.	.		T	T								T	T						T	T				B				.	.	.	.	.	.	.			G	G	G								S		B
Template Predicted Secondary structure																.	.	.	.																											.	.	.	.	.	.	.
Template SS confidence
		1019	1020	.	.	.	.	.	.	.	.	.	1030	.	.					.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.								.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.
		364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.										.	.	.	.	.	.	.	390	.	.	.						.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.		.	.	.
Predicted Secondary structure																					.	.	.	.	.	.	.	.	.												.	.	.	.	.																																	.
Query SS confidence																					.	.	.	.	.	.	.	.	.												.	.	.	.	.																																	.
Query Sequence		R	T	V	C	E	P	I	F	E	K	P	L	A	E	I	S	F	G	H	.	.	.	.	.	.	.	.	.	V	L	L	N	L	F	N	T	A	R	R	.	.	.	.	.	F	N	M	E	V	Q	P	Q	L	V	L	L	Q	K	T	L	L	Y	V	E	G	V	G	R	Q	L	Y	P	Q	L	D	L	.	W	K	T
Query Conservation																					.	.	.	.	.	.	.	.	.												.	.	.	.	.																																	.
Alig confidence																					.	.	.	.	.	.	.	.	.												.	.	.	.	.																.	.	.	.	.	.	.											.
Template Conservation																																																													.	.	.	.	.	.	.
Template Sequence		Y	E	L	L	T	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	A	Q	G	Q	M	T	V	L	R	L	T	E	L	L	E	R	G	E	R	L	P	R	P	D	K	C	P	A	E	V	Y	H	L	M	K	N	.	.	.	.	.	.	.	C	W	E	T	E	A	S	F	R	P	T	F	E	N
Template Known Secondary structure						T	T	T		G	G	G	S											S	T	T	G	G	G											T	T							T	T												.	.	.	.	.	.	.		T		S	S	G	G	G	S
Template Predicted Secondary structure																																																													.	.	.	.	.	.	.
Template SS confidence
		1092	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150								.	.	.	.	.	.	.	.	.	1160	.	.	.	.
		429	430	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	K	P	F	L	E	S	W	I	K	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	I	P	I	L	K	T	V	H	E	K
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		1165	.	.	.	.	1170	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions