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Job DescriptionP0A6A0
Confidence99.63%DateThu Jan 5 11:02:40 GMT 2012
Rank190Aligned Residues220
% Identity14%Templatec3fmeA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6; PDBTitle: crystal structure of human mitogen-activated protein kinase kinase 62 (mek6) activated mutant (s207d, t211d)
Resolution2.26 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   128.130.........140.........150.........160.........170.........180.........190.........200.......
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Query Sequence  KPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLL
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Template Sequence  MELGRGAYGVVEKMRHVPSGQIMAVKRIRNS. . . . . . . . . . . . QEQKRLLMDLDISMRTVDCPFTVTFYG. . . . . . . . . .
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SSTTTT

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   57..60.........70.........80....... ..90.........100.........110....
 
   208.210.........220.........230.........240.........250.........260... ......270.........280..
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Query Sequence  RESANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTN. . . . . MKLLAERGVQVFFTQVFRD
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . ALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKL
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   118.120.........130.........140.........150.........160.........170...
 
   283......290.........300.........310.........320.........330.........340.........350.........360..
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Query Sequence  SFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFA
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Template Sequence  SVIHRDVKPSNVLIN. . . . ALGQVKMCDFAGCK. . . . . . . . . . . . . . . . . . . . PYMAPERINPELNQYSVKSDIWSLGIT
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SGGG

....TT

B






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   174.....180........ .190.........200.. .......210.........220.........
 
   363......370.........380.........390...... ...400.........410.......
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Query Sequence  IRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNM. EVQPQLVLLQKTLLYVEGVGR
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Template Sequence  MIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKER
Template Known Secondary structure  TS
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S
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TTTS
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   247..250.........260.........270.........280.........290.........300..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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