Job Description P0A6A0 Confidence 99.81% Date Thu Jan 5 11:02:40 GMT 2012 Rank 98 Aligned Residues 249 % Identity 16% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.					.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.
Predicted Secondary structure																			.	.	.	.
Query SS confidence																			.	.	.	.
Query Sequence		K	P	L	A	S	A	S	I	A	Q	V	H	T	A	R	L	K	.	.	.	.	S	N	G	K	E	V	V	I	K	V	I	R	P	D	I	L	P	V	I	K	A	D	L	K	L	I	Y	R	L	A	R	W	V	P	R	L	L	P	D	G	R	R	L	R	P	T	E	V	V	R	E	Y	E	K	T	L	I	D	E
Query Conservation																			.	.	.	.
Alig confidence																			.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																					.	.	.	.	.	.	.
Template Conservation																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																					.	.	.	.	.	.	.
Template Sequence		R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	P	H	I	A	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	K	K	E	I	E	I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	.	.	.	.	.	.	.
Template Known Secondary structure								S	S										T	T	S	S	S		S															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.										T				T	T	B					.	.	.	.	.	.	.
Template Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																					.	.	.	.	.	.	.
Template SS confidence
		879	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.																.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.			.	.	.	.	.	280	.
Predicted Secondary structure																																																																									.	.
Query SS confidence																																																																									.	.
Query Sequence		L	N	L	L	R	E	S	A	N	A	I	Q	L	R	R	N	F	E	D	S	P	M	L	Y	I	P	E	V	Y	P	D	Y	C	S	E	G	M	M	V	M	E	R	I	Y	G	I	P	V	S	D	V	A	A	L	E	K	N	G	T	N	M	K	L	L	A	E	R	G	V	Q	V	.	.	F	F	T	Q	V	F	R
Query Conservation																																																																									.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																												.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	I	C	T	E	N	G	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																T	T		B					T	G	G	G	T	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																														942	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.
		282	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	S	F	F	H	A	D	M	H	P	G	N	I	F	V	S	Y	E	H	P	E	N	P	K	Y	I	G	I	D	C	G	I	V	G	S	L	N	K	E	D	K	R	Y	L	A	E	N	F	I	A	F	F	N	R	D	Y	R	K	V	A	E	L	H	V	D	S	G	W	V	P	P	D	T	N	V	E	E	F	E	F
Query Conservation
Alig confidence																		.	.	.	.																																										.	.	.	.	.
Template Conservation																		.	.	.	.																																										.	.	.	.	.
Template Sequence		R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	.	.	.	.	S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A	I	E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A	P	E	C	L	M	Q	.	.	.	.	.	S	K	F	Y	I	A	S	D	V	W	S	F	G	V
Template Known Secondary structure		T	T				S			S	G	G	G					.	.	.	.		T	T								T	T						T	T					S			T	T			G	G	G									.	.	.	.	.
Template Predicted Secondary structure																		.	.	.	.																																										.	.	.	.	.
Template SS confidence
		997	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.					.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.						.	.	.	.	.	.	1060	.	.	.	.	.	.	.
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.											.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.		.	.	.	.	430
Predicted Secondary structure																						.	.	.	.	.	.	.	.	.	.																																													.
Query SS confidence																						.	.	.	.	.	.	.	.	.	.																																													.
Query Sequence		A	I	R	T	V	C	E	P	I	F	E	K	P	L	A	E	I	S	F	G	.	.	.	.	.	.	.	.	.	.	H	V	L	L	N	L	F	N	T	A	R	R	F	N	M	E	V	Q	P	Q	L	V	L	L	Q	K	T	L	L	Y	V	E	G	V	G	R	Q	L	Y	P	Q	L	D	L	.	W	K	T	A	K
Query Conservation																						.	.	.	.	.	.	.	.	.	.																																													.
Alig confidence																						.	.	.	.	.	.	.	.	.	.																																.	.	.											.
Template Conservation																																																															.	.	.
Template Sequence		T	L	H	E	L	L	T	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T	R	L	V	N	T	L	K	E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	.	.	.	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I
Template Known Secondary structure								T	T	T		G	G	G												S			G	G	G											T	T							T	T												.	.	.	T			S	S	G	G	G	S
Template Predicted Secondary structure																																																															.	.	.
Template SS confidence
		1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130				.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.
		431	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	F	L	E	S	W	I	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	G	F	E	A	L	L	K
Template Known Secondary structure						T	T
Template Predicted Secondary structure
Template SS confidence
		1147	.	.	1150	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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