|   |
128 | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | P | L | A | S | A | S | I | A | Q | V | H | T | A | R | L | K | S | N | G | K | E | V | V | I | K | V | I | R | P | D | I | L | P | V | I | K | A | D | L | K | L | I | Y | R | L | A | R | W | V | P | R | L | L | P | D | G | R | R | L | R | P | T | E | V | V | R | E | Y | E | K | T | L | I | D | E | L | N | L | L |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |
|   |   |
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|   |
|
|   |
|   |   | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
R | V | L | G | R | G | G | F | G | E | V | F | A | C | Q | M | K | A | T | G | K | L | Y | A | C | K | K | L | N | K | K | R | L | K | K | . |
. |
. |
. |
. |
. |
. |
. |
R | K | G | Y | Q | G | A | M | V | E | K | K | I | L | A | K | V | H | S | R | F | I | V | S | L | A | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |
|
|
| S | S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | T | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
| B |
|  | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
191 | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
|
|
|
|
|
|
|
|
|
  |
  |   |
208 | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | |
|
|
. | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
. | . | . | . | . | 280 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
R | E | S | A | N | A | I | Q | L | R | R | N | F | E | D | S | P | M | L | Y | I | P | E | V | Y | P | D | Y | C | S | E | G | M | M | V | M | E | R | I | Y | G | I | P | V | S | D | V | A | A | L | . |
. |
. |
E | K | N | G | T | N | M | K | L | L | A | E | R | G | V | Q | V | . |
. |
F | F | T | Q | V | F | R | D |
Query Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . |   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | F | E | T | K | T | D | L | C | L | V | M | T | I | M | N | G | G | D | I | R | Y | H | I | Y | N | V | D | E | D | N | P | G | F | Q | E | P | R | A | I | F | Y | T | A | Q | I | V | S | G | L | E | H | L | H | Q | R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
| S | S |  |  |  |  |  |  |
|
|
|
| S |  |  |  |  |  |  |  | T | T | T | S | S | S | S |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
  |
  |   |
283 | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
Predicted Secondary structure |   |
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | F | F | H | A | D | M | H | P | G | N | I | F | V | S | Y | E | H | P | E | N | P | K | Y | I | G | I | D | C | G | I | V | G | S | L | N | K | E | D | K | R | Y | L | A | E | N | F | I | A | F | F | N | R | D | Y | R | K | V | A | E | L | H | V | D | S | G | W | V | P | P | D | T | N | V | E | E | F | E | F | A |
Query Conservation |   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|
|   |
|
|
|
|   | . | . | . | . |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
Template Sequence |   |
N | I | I | Y | R | D | L | K | P | E | N | V | L | L | D | . |
. |
. |
. |
D | D | G | N | V | R | I | S | D | L | G | L | A | V | E | L | K | A | G | Q | T | K | T | K | G | Y | A | . |
. |
. |
. |
. |
. |
G | T | P | G | F | M | A | P | E | L | L | L | G | E | E | Y | D | F | S | V | D | Y | F | A | L | G | V | T |
Template Known Secondary structure |   |
S | B |
|
|
|
|
|
| G | G | G |  |  |  |
| . | . | . | . | S | S | S |
|  |  |  |
|
|
| S | S |
|
| B |
|
| S | S |
|
|
| B |
|
|
|
| . | . | . | . | . | . | S |
| T | T | T | S |
|  |  |  |  | T | T |
|
| B |
| T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|  |  |  |  |
| . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | |
|
|
|
. | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . |
  |
  |   |
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | R | T | V | C | E | P | I | F | E | K | P | L | A | E | I | S | F | G | H | V | L | L | N | L | F | N | T | A | R | R | F | N | M | E | V | Q | P | Q | L | V | L | L | Q | K | T | L | L | Y | V | E | G | V | G | R | Q | L | Y | P | Q | L | D | L |
Query Conservation |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |   |
|
|
|   |   |   |   |
|
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|   |   |
|
| . | . | . | . | . | . | . |   |   |
|
|   |   |
|
|
Template Sequence |   |
L | Y | E | M | I | A | A | R | G | P | F | R | A | R | G | V | E | N | K | E | L | K | Q | R | V | L | E | Q | A | V | T | Y | P | D | K | F | S | P | A | S | K | D | F | C | E | A | L | L | . |
. |
. |
. |
. |
. |
. |
Q | K | D | P | E | K | R | L |
Template Known Secondary structure |   |
 |  |  |  | T | T | S | S |
| S | S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . |
| S | S | S | S | S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
379 | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 430 | . | . | . | . |
  |