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Job DescriptionP0A6A0
Confidence99.91%DateThu Jan 5 11:02:40 GMT 2012
Rank14Aligned Residues230
% Identity18%Templatec2h8hA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   130.........140.........150.........160.........170.........180.........190.........200.........
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Query Sequence  LASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRE
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Template Sequence  LGQGCFGEVWMGTWN. GTTRVAIKTLKPGTMSP. . . . . . . . . . . . EAFLQEAQVMKKLRHEKLVQLYA. . . . . . . . . . . .
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   273......280....... ..290.........300.... .....310.........320.......
 
   210.........220.........230.........240.........250..... ....260.........270.... .....280......
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Query Sequence  SANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVA. ALEKNGTNMKLLAERGVQV. . FFTQVFRDSFFH
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . VVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVH
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   328.330 .........340.........350.........360.........370.........380....
 
   287..290.........300.........310.........320.........330.........340.........350.........360......
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Query Sequence  ADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTV
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Template Sequence  RDLRAANILVG. . . . ENLVCKVADFGLARLIEDNEYTARQGAK. . . . . FPIKWTAPEAALYGRFTIKSDVWSFGILLTEL
Template Known Secondary structure  S

SGGG
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   385....390..... ....400.........410.........420... ......430.........440.........450.....
 
   367..370.........380.........390....... ..400.........410.......
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Query Sequence  CEPIFEKPLAEISFGHVLLNLFNTARRFNME. VQPQLVLLQKTLLYVEGVGR
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Template Sequence  TT. KGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEER
Template Known Secondary structure  TT.TT

SSTT

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TT

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   456. ..460.........470.........480.........490.........500......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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