Job Description P0A6A0 Confidence 99.74% Date Thu Jan 5 11:02:40 GMT 2012 Rank 142 Aligned Residues 240 % Identity 12% Template c1xkkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016 Resolution 2.40 Å

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		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	P	L	A	S	A	S	I	A	Q	V	H	T	A	R	L	K	S	N	G	K	E	V	V	I	K	V	I	R	P	D	I	L	P	V	I	K	A	D	L	K	L	I	Y	R	L	A	R	W	V	P	R	L	L	P	D	G	R	R	L	R	P	T	E	V	V	R	E	Y	E	K	T	L	I	D	E	L	N	L	L
Query Conservation
Alig confidence																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	V	L	G	S	G	A	F	G	T	V	Y	K	G	L	W	I	P	V	K	I	P	V	A	I	K	E	L	R	E	K	A	N	K	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	L	D	E	A	Y	V	M	A	S	V	D	N	P	H	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure								S	S																								T				.	.	.	.	.	.	.	.	.	.	.	.	.	.														T	T	B	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		716	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750															.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.			.	.	.	.	.	280	.	.	.	.	.
Predicted Secondary structure																																																																					.	.
Query SS confidence																																																																					.	.
Query Sequence		R	E	S	A	N	A	I	Q	L	R	R	N	F	E	D	S	P	M	L	Y	I	P	E	V	Y	P	D	Y	C	S	E	G	M	M	V	M	E	R	I	Y	G	I	P	V	S	D	V	A	A	L	E	K	N	G	T	N	M	K	L	L	A	E	R	G	V	Q	V	.	.	F	F	T	Q	V	F	R	D	S	F	F
Query Conservation																																																																					.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	C	R	L	L	G	I	C	L	T	S	T	V	Q	L	I	T	Q	L	M	P	F	G	C	L	L	D	Y	V	R	E	H	K	D	N	I	G	S	Q	Y	L	L	N	W	C	V	Q	I	A	K	G	M	N	Y	L	E	D	R	R	L	V
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.									S	S	S									T	T		B								T	S	S	S																							T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																						775	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.
		286	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	A	D	M	H	P	G	N	I	F	V	S	Y	E	H	P	E	N	P	K	Y	I	G	I	D	C	G	I	V	G	S	L	N	K	E	D	K	R	Y	L	A	E	N	F	I	A	F	F	N	R	D	Y	R	K	V	A	E	L	H	V	D	S	G	W	V	P	P	D	T	N	V	E	E	F	E	F	A	I	R	T
Query Conservation
Alig confidence														.	.	.	.																				.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation														.	.	.	.																				.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		H	R	D	L	A	A	R	N	V	L	V	K	.	.	.	.	T	P	Q	H	V	K	I	T	D	F	G	L	A	K	L	L	G	A	E	.	.	.	.	.	.	.	.	.	.	.	.	E	K	V	P	I	K	W	M	A	L	E	S	I	L	H	R	I	Y	T	H	Q	S	D	V	W	S	Y	G	V	T	V	W	E
Template Known Secondary structure			S				G	G	G					.	.	.	.		T	T								S					T	T	T	T	.	.	.	.	.	.	.	.	.	.	.	.					T	T	T	S
Template Predicted Secondary structure														.	.	.	.																				.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		835	.	.	.	.	840	.	.	.	.	.	.					.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.													.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.		.	.	.	.	430	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																														.
Query SS confidence																																																														.
Query Sequence		V	C	E	P	I	F	E	K	P	L	A	E	I	S	F	G	H	V	L	L	N	L	F	N	T	A	R	R	F	N	M	E	V	Q	P	Q	L	V	L	L	Q	K	T	L	L	Y	V	E	G	V	G	R	Q	L	Y	P	Q	L	D	L	.	W	K	T	A	K	P	F	L	E	S	W	I	K	D
Query Conservation																																																														.
Alig confidence																																													.	.	.	.	.	.	.											.
Template Conservation																																													.	.	.	.	.	.	.
Template Sequence		L	M	T	F	G	S	K	P	Y	D	G	I	P	A	S	E	I	S	S	I	L	E	K	G	E	R	L	P	Q	P	P	I	C	T	I	D	V	Y	M	I	M	V	K	.	.	.	.	.	.	.	C	W	M	I	D	A	D	S	R	P	K	F	R	E	L	I	I	E	F	S	K	M	A	R	D
Template Known Secondary structure				T	T	S			T	T	T	T	S		G	G	G								T							T	T	B											.	.	.	.	.	.	.		T		S	S	G	G	G	S																S
Template Predicted Secondary structure																																													.	.	.	.	.	.	.
Template SS confidence
		907	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.								950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions