Return to main results Retrieve Phyre Job Id

Job DescriptionP0A6A0
Confidence99.92%DateThu Jan 5 11:02:40 GMT 2012
Rank11Aligned Residues263
% Identity13%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   128.130.........140.........150.........160.........170.........180.........190.........200.......
Predicted Secondary structure 

















Query SS confidence 















































































Query Sequence  KPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLL
Query Conservation   












 
   
  




 

 
      

  
                     

 
       



 
Alig confidence 


































............






















..........
Template Conservation    

 
 

 
           



 

      ............  
  
  

  
 
 


 
 
..........
Template Sequence  HKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEV. . . . . . . . . . . . EEFLKEAAVMKEIKHPNLVQLLG. . . . . . . . . .
Template Known Secondary structure  SGGGTTSSGGGT

SSSS
............


TTB

..........
Template Predicted Secondary structure 














............




..........
Template SS confidence 















































































   265....270.........280.........290......... 300.........310.........320..
 
   208.210.........220.........230.........240.........250.........260.. .......270.........280....
Predicted Secondary structure 
























...


Query SS confidence 






















































. . .





















Query Sequence  RESANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGT. . . NMKLLAERGVQVFFTQVFRDSF
Query Conservation   

 
             
 

 
        




 
 
  
           ...    
        
      
 
Alig confidence  ........................






























...





















Template Conservation  ........................         




   


   
                  

  

 


    
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . VCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF
Template Known Secondary structure  ........................
SSSS


TT
BS
TTTS
TT
Template Predicted Secondary structure  ........................




















Template SS confidence 















































































   323......330.........340.........350.........360.........370........
 
   285....290.........300.........310.........320.........330.........340.........350.........360....
Predicted Secondary structure 





























Query SS confidence 















































































Query Sequence  FHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIR
Query Conservation   


 






      

 
 




    
    
             
           
      
   
   
 
Alig confidence 












....



























.....





























Template Conservation 




   


  ....     

 




               .....      


       
 








 
 
Template Sequence  IHRNLAARNCLVG. . . . ENHLVKVADFGLSRLMTGDTYTAHAGAK. . . . . FPIKWTAPESLAYNKFSIKSDVWAFGVLLW
Template Known Secondary structure 
S

SGGG
....GGG


TT


TT



TT

.....

GGG



Template Predicted Secondary structure 







....

















.....






Template SS confidence 















































































   379380.........390. ........400.........410......... 420.........430.........440.........
 
   365....370.........380.........390.........400.........410.........420..... ....430.........440...
Predicted Secondary structure 



















.


Query SS confidence 




























































.

















Query Sequence  TVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDL. WKTAKPFLESWIKDQVGI
Query Conservation   

                               
     
 
 
  


    


    .                  
Alig confidence 



.

















...





















...









.

















Template Conservation 

 
. 
  
            
...  
 
   
   
  
  

  ...
   

  


   
   
          
Template Sequence  EIAT. YGMSPYPGIDLSQVYELL. . . EKDYRMERPEGCPEKVYELMRA. . . CWQWNPSDRPSFAEIHQAFETMFQESSIS
Template Known Secondary structure  T.TS

SSTT

TTT...TT





TT

...T
SSGGGS

TS
SSS
Template Predicted Secondary structure  .









...











...










Template SS confidence 















































































   450... ......460.........470. ........480.........490... ......500.........510.........520..
 
   444.....450..
Predicted Secondary structure 
Query SS confidence 








Query Sequence  PALVRAFKE
Query Conservation           
Alig confidence 








Template Conservation        
  
Template Sequence  DEVEKELGK
Template Known Secondary structure 
Template Predicted Secondary structure 

Template SS confidence 








   523......530.
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions