Job Description P27550 Confidence 100.00% Date Thu Jan 5 11:44:02 GMT 2012 Rank 9 Aligned Residues 517 % Identity 24% Template c3eynB_ PDB info PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa Resolution 1.90 Å

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		68	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.						.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.		.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.
Predicted Secondary structure																				.	.	.	.	.																																									.
Query SS confidence																				.	.	.	.	.																																									.
Query Sequence		K	W	Y	E	D	G	T	L	N	L	A	A	N	C	L	D	R	H	.	.	.	.	.	L	Q	E	N	G	D	R	T	A	I	I	W	E	G	D	D	A	S	Q	S	K	H	I	S	Y	K	E	L	H	R	D	V	C	R	F	A	N	T	L	L	.	E	L	G	I	K	K	G	D	V	V	A	I	Y	M	P	M
Query Conservation																				.	.	.	.	.																																									.
Alig confidence																				.	.	.	.	.																	.																								.
Template Conservation																																									.
Template Sequence		H	Q	E	V	P	A	K	F	N	F	A	S	D	V	L	D	H	W	A	D	M	E	K	A	G	K	R	P	P	S	P	A	L	W	W	V	N	G	K	.	G	K	E	L	M	W	N	F	R	E	L	S	E	N	S	Q	Q	A	A	N	V	L	S	G	A	C	G	L	Q	R	G	D	R	V	A	V	V	L	P	R
Template Known Secondary structure		B					S	B							T										T	T	S	S											S	S	.	S																							T	T	T				T	T									S
Template Predicted Secondary structure																																									.
Template SS confidence
		37	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.		.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.
		142	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	P	E	A	A	V	A	M	L	A	C	A	R	I	G	A	V	H	S	V	I	F	G	G	F	S	P	E	A	V	A	G	R	I	I	D	S	N	S	R	L	V	I	T	S	D	E	G	V	R	A	G	R	S	I	P	L	K	K	N	V	D	D	A	L	K	N	P	N	V	T	S	V	E	H	V	V	V	L	K
Query Conservation
Alig confidence																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	P	E	W	W	L	V	I	L	G	C	I	R	A	G	L	I	F	M	P	G	T	I	Q	M	K	S	T	D	I	L	Y	R	L	Q	M	S	K	A	K	A	I	V	A	G	D	E	V	I	Q	E	V	D	T	V	A	S	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	C	P
Template Known Secondary structure															T	T								T	T														T		S						T	T	T								G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.		T
Template Predicted Secondary structure																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		116	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.																					.	.
		222	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	T	G	G	K	I	D	W	Q	E	G	R	D	L	W	W	H	D	L	V	E	Q	A	S	D	Q	H	Q	A	E	E	M	N	A	E	D	P	L	F	I	L	Y	T	S	G	S	T	G	K	P	K	G	V	L	H	T	T	G	G	Y	L	V	Y	A	A	L	T	F	K	Y	V	F	D	Y	H	P	G	D	I	Y
Query Conservation
Alig confidence																																																																				.
Template Conservation																																																																				.
Template Sequence		S	L	R	I	K	L	L	V	S	E	K	S	C	D	G	W	L	N	F	K	K	L	L	N	E	A	S	T	T	H	H	C	V	E	T	G	S	Q	E	A	S	A	I	Y	F	T	S	G	L	P	K	M	A	E	H	S	Y	S	S	L	G	L	K	A	K	M	.	D	A	G	W	T	G	L	Q	A	S	D	I	M
Template Known Secondary structure		T								S	S	S			T	T											S		S								B	T	T	S																												.		T	T	T	T	S			T	T
Template Predicted Secondary structure																																																																				.
Template SS confidence
		176	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.		.	.	.	.	.	.	.	.	250	.	.	.	.
		302	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	C	T	A	D	V	G	W	V	T	G	H	S	Y	L	L	Y	G	P	L	A	C	G	A	T	T	L	M	F	E	G	V	P	N	W	P	T	P	A	R	M	A	Q	V	V	D	K	H	Q	V	N	I	L	Y	T	A	P	T	A	I	R	A	L	M	A	E	G	D	K	A	I	E	G	T	D	R	S	S	L	R
Query Conservation
Alig confidence																																		.	.																																				.	.	.
Template Conservation																																		.	.																																				.	.	.
Template Sequence		W	T	I	S	D	T	G	W	I	L	N	I	L	C	S	L	M	E	P	W	A	L	G	A	C	T	F	V	H	L	L	P	.	.	K	F	D	P	L	V	I	L	K	T	L	S	S	Y	P	I	K	S	M	M	G	A	P	I	V	Y	R	M	L	L	Q	Q	D	L	S	.	.	.	S	Y	K	F	P	H	L	Q
Template Known Secondary structure							T	T	S							T	T							T									S	.	.	S													S																	T	S		T	T	.	.	.	S	S			T	T
Template Predicted Secondary structure																																		.	.																																				.	.	.
Template SS confidence
		258	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.			290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.				.	.	.	.	.	330	.	.
		382	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	L	G	S	V	G	E	P	I	N	P	E	A	W	E	W	Y	W	K	K	I	G	N	E	K	C	P	V	V	D	T	W	W	Q	T	E	T	G	G	F	M	I	T	P	L	P	G	A	T	E	L	K	A	G	S	A	T	R	P	F	F	G	V	Q	P	A	L	V	D	N	E	G	N	P	L	E	G	A	T	E
Query Conservation
Alig confidence																							.	.	.																						.	.
Template Conservation																							.	.	.																						.	.
Template Sequence		N	C	V	T	V	G	E	S	L	L	P	E	T	L	E	N	W	R	A	Q	T	.	.	.	G	L	D	I	R	E	S	Y	G	Q	T	E	T	G	L	T	C	M	V	S	K	.	.	T	M	K	I	K	P	G	Y	M	G	T	A	A	S	C	Y	D	V	Q	I	I	D	D	K	G	N	V	L	P	P	G	T	E
Template Known Secondary structure							S	S															.	.	.	S										T	T	T								T	.	.	T	S				T	T							T	T								T	T	S		B			T	T
Template Predicted Secondary structure																							.	.	.																						.	.
Template SS confidence
		333	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.				.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.			.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
		462	.	.	.	.	.	.	.				470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.
Predicted Secondary structure										.	.	.
Query SS confidence										.	.	.
Query Sequence		G	S	L	V	I	T	D	S	.	.	.	W	P	G	Q	A	R	T	L	F	G	D	H	E	R	F	E	Q	T	Y	F	S	T	F	K	N	M	Y	F	S	G	D	G	A	R	R	D	E	D	G	Y	Y	W	I	T	G	R	V	D	D	V	L	N	V	S	G	H	R	L	G	T	A	E	I	E	S	A	L	V	A
Query Conservation										.	.	.
Alig confidence										.	.	.																				.	.	.
Template Conservation																																.	.	.
Template Sequence		G	D	I	G	I	R	V	K	P	I	R	P	I	G	I	F	S	G	Y	V	D	N	P	D	K	T	A	A	N	I	.	.	.	R	G	D	F	W	L	L	G	D	R	G	I	K	D	E	D	G	Y	F	Q	F	M	G	R	A	D	D	I	I	N	S	S	G	Y	R	I	G	P	S	E	V	E	N	A	L	M	E
Template Known Secondary structure									S	S	B			T	T	S					T	T								T		.	.	.		T	T												T	T	S								G	G	G					T	T														T
Template Predicted Secondary structure																																.	.	.
Template SS confidence
		408	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.				.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.
		539	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.			.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.
Predicted Secondary structure																																					.	.
Query SS confidence																																					.	.
Query Sequence		H	P	K	I	A	E	A	A	V	V	G	I	P	H	N	I	K	G	Q	A	I	Y	A	Y	V	T	L	N	H	G	E	E	P	S	P	.	.	E	L	Y	A	E	V	R	N	W	V	R	K	E	I	G	P	L	A	T	P	D	V	L	H	W	T	D	S	L	P	K	T	R	S	G	K	I	M	R	R	I	L	R
Query Conservation																																					.	.
Alig confidence																																					.	.
Template Conservation
Template Sequence		H	P	A	V	V	E	T	A	V	I	S	S	P	D	P	V	R	G	E	V	V	K	A	F	V	V	L	A	S	Q	F	L	S	H	D	P	E	Q	L	T	K	E	L	Q	Q	H	V	K	S	V	T	A	P	Y	K	Y	P	R	K	I	E	F	V	L	N	L	P	K	T	V	T	G	K	I	Q	R	A	K	L	R
Template Known Secondary structure		S	T	T												T	T	T												G	G	G	G	G	S																	S		G	G	G	S		S						S				B		T	T			B
Template Predicted Secondary structure
Template SS confidence
		485	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.
		617	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	I	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	K	E
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		565	.	.