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Job DescriptionP39362
Confidence98.88%DateThu Jan 5 11:59:53 GMT 2012
Rank111Aligned Residues165
% Identity13%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   12.......20.........30.........40...... ...50.........60...... ...70.....
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Query Sequence  PLHYGRELTALDNLDFGSLHLDIEDSSFINNITFG. . . . . . . . . . . . MKTVQAVARQTPHPLSFHFM. . . . LARPQRWFN
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Template Sequence  AEDYAEGVRVLGP. LADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIAS
Template Known Secondary structure  GG.G
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TTSTTSGGGGSTS
GGG


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   192.......200.... .....210.........220.........230.........240.........250.........260.........270
 
   76...80.........90.........100.........110.........120.........130.........140.........150.....
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Query Sequence  ALAEIRPAWIFVHAETLDYPSETLTEIRHTGARAGLVFNPATPIDAWRYLASELDGVMVMTSEPDGQGQRFIPSMCEKIQ
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Template Sequence  VVKELGIDGLIVTNTTVSR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PAGLQGALRSETGGLSGKPLRDLSTQTIR
Template Known Secondary structure  T




BS

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   271........280......... 290.........300.........310........
 
   156...160.. .......170.. .......180.........190... ......200.... .....
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Query Sequence  KVRTAFP. QTECWADGGI. TLAAAQQLAAAGAQHMVIGRA. LFSSSDYRATL. AQFAT
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Template Sequence  EMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEA
Template Known Secondary structure  TTT
S
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   319320.........330.........340.........350.........360.........370......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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