Job Description P39362 Confidence 97.68% Date Thu Jan 5 11:59:53 GMT 2012 Rank 226 Aligned Residues 174 % Identity 11% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		11	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.			.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.
Predicted Secondary structure																																							.	.																																									.
Query SS confidence																																							.	.																																									.
Query Sequence		N	P	L	H	Y	G	R	E	L	T	A	L	D	N	L	D	F	G	S	L	H	L	D	I	E	D	S	S	F	I	N	N	I	T	F	G	M	.	.	K	T	V	Q	A	V	A	R	Q	T	P	H	P	L	S	F	H	F	M	L	A	R	P	Q	R	W	F	N	A	L	A	E	I	R	P	A	W	I	F	V	.
Query Conservation																																							.	.																																									.
Alig confidence																								.	.	.	.												.	.																																									.
Template Conservation																								.	.	.	.
Template Sequence		S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	.	.	.	.	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V	I	F
Template Known Secondary structure																T	T		S					.	.	.	.						T	T	T		G	G	G	T	T								S				T	T		B							S										T	T		S
Template Predicted Secondary structure																								.	.	.	.
Template SS confidence
		52	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.					.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.
																	88	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.									.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.		.	140	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																														.	.	.	.	.	.	.	.																							.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																														.	.	.	.	.	.	.	.																							.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	A	E	T	L	D	Y	P	S	E	T	L	T	E	I	R	H	T	G	A	R	A	G	L	V	F	N	P	A	.	.	.	.	.	.	.	.	T	P	I	D	A	W	R	Y	L	A	S	E	L	D	G	V	M	V	M	T	S	E	.	P	D	G	Q	G
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																														.	.	.	.	.	.	.	.																							.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																														.	.	.	.	.	.	.	.																							.
Template Conservation
Template Sequence		G	A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	I	S	L	G	D	T	I	G
Template Known Secondary structure				S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S																T	T		S							T	T
Template Predicted Secondary structure
Template SS confidence
		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
		144	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.					.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.
Predicted Secondary structure																											.	.	.	.
Query SS confidence																											.	.	.	.
Query Sequence		Q	R	F	I	P	S	M	C	E	K	I	Q	K	V	R	T	A	F	P	Q	T	E	C	W	A	.	.	.	.	D	G	G	I	T	L	A	A	A	Q	Q	L	A	A	A	G	A	Q	H	M
Query Conservation																											.	.	.	.
Alig confidence																											.	.	.	.
Template Conservation
Template Sequence		V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V
Template Known Secondary structure																			S		G	G	G						B		T	T	S												T	T
Template Predicted Secondary structure
Template SS confidence
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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