|   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | L | T | L | L | A | G | M | L | R | E | K | L | G | W | D | I | E | P | Q | N | I | A | L | T | N | G | S | Q | S | A | F | F | Y | L | F | N | L | F | A | G | R | R | A | D | G | R | V | K | K | V | L | F | P | L | A | P | E | Y | I | G | Y | A | D | A | G | L | E | E | D | L | F | V | S | A | R | P | N | I |
Query Conservation |   |
  |
|
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   | . | . | . | . | . | . |   |
|   |
|   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |
Template Sequence |   |
A | L | T | N | K | I | L | E | S | F | F | K | Q | L | G | L | N | V | H | A | I | A | T | P | I | S | T | G | X | S | I | S | L | C | L | S | A | A | R | K | K | Y | G | S | N | V | V | I | Y | P | Y | A | . |
. |
. |
. |
. |
. |
S | H | K | S | P | I | K | A | V | S | F | V | G | X | N | X | R | L | V | E | T | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . |
  |
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | L | P | E | G | Q | F | K | Y | H | V | D | F | E | H | L | H | I | G | E | . |
. |
. |
. |
. |
E | T | G | M | I | C | V | S | R | P | T | N | P | T | G | N | V | I | T | D | E | E | L | L | K | L | D | A | L | A | N | Q | H | G | I | P | L | V | I | D | N | A | Y | G | V | P | F | P | G | I | I | F | S | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | D | . |
. |
G | D | R | V | Y | V | P | V | E | D | I | E | N | A | I | K | K | E | I | E | L | G | N | R | P | C | V | L | S | T | L | T | F | F | P | P | R | N | S | D | D | . |
. |
. |
I | V | E | I | A | K | I | C | E | N | Y | D | I | P | H | I | I | N | G | A | Y | A | I | Q | N | N | Y | Y | L | E | K | L |
Template Known Secondary structure |   |
 |  | . | . | T | T |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  | S | S |
|
| T | T | B |
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| T | T | T | T | T |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
187 | . | |
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | |
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
  |
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|  |  |
|
|  |  |  |  |  |  | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | R | P | L | W | N | P | N | I | V | L | C | M | S | L | S | K | L | G | L | P | G | S | R | C | G | I | I | I | A | . |
N | E | K | I | I | T | A | I | T | N | M | N | G | I | I | S | L | A | P | G | G | I | G | P | A | M | M | C | E | M | I | K | R | N | D | L | L | R | L | S | E | T | V | I | K | P | F | Y | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |
|   |
|   |
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
|   |
|   |   |
|   |
|
|   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |
|   |   |
|
|   |   |   |
| . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | K | A | F | K | Y | R | V | D | A | V | V | S | S | S | D | K | N | L | L | T | P | I | G | G | G | L | V | Y | S | T | D | A | E | F | I | K | E | I | S | L | S | Y | P | G | R | A | S | A | T | P | V | V | N | T | L | V | S | L | L | S | X | G | . |
. |
. |
. |
. |
S | K | N | Y | L | E | L | V | K | N | Q | K |
Template Known Secondary structure |   |
 |  |  |  | T | S |
|
| S |  |  |  |  |  |  |  |  |  |  |
|
|
| S | S |
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  | T | T | S |
| S |
| B |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 330 | . | . | . | . | . | . |
  |
  |   |
312 | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | |
|
|
|
. | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | R | V | Q | E | T | I | A | I | I | R | R | Y | L | P | E | N | R | C | L | I | H | K | P | E | G | A | I | F | L | W | L | W | F | K | D | L | P | I | T | T | K | Q | L | Y | Q | R | L | K | A | R | G | V | . |
. |
. |
. |
L | M | V | P | G | H | N | F | F | P | G | L | D | K | P | W | P | H | T | H | Q | C | M |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
| . | . | . | . |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|
|   |   |
|   |
| . | . | . |   |   |
|   |   |
|
|   |   |   |
|   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
N | S | K | K | L | L | D | E | L | L | N | D | L | S | K | K | T | G | G | K | F | L | D | V | E | S | P | I | A | S | C | I | S | V | . |
. |
. |
N | S | D | P | V | E | I | A | A | K | L | Y | N | L | R | V | T | G | P | R | G | I | K | K | T | D | H | F | G | N | C | Y | L | G | T | Y | T | H | D | Y | I | V | X |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
| B |
|
|
|
|
| S | S |  |  |  |  |  |
| . | . | . | S | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|  |  |  |
| T | T |
|  |  |  |  | T |
| S | S |
|
| S |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
337 | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | |
|
|
. | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . |
  |
  |   |
388 | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | M | N | Y | V | P | E | P | E | K | I | E | A | G | V | K | I | L | A | E |
Query Conservation |   |
|
|
|   |   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|   |
|   |
|
|
|
|   |
|
|   |   |
|   |
|
Template Sequence |   |
N | A | A | I | G | V | R | T | E | D | I | V | N | S | V | S | K | L | E | K |
Template Known Secondary structure |   |
 |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
414 | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . |
  |