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Job DescriptionP09053
Confidence99.97%DateThu Jan 5 11:01:50 GMT 2012
Rank94Aligned Residues347
% Identity15%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2930.........40..... ....50.........60.........70.........80.........90.........100.......
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Query Sequence  TPGAIMLGGGNPAQIPE. MQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIALTNGSQ
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Template Sequence  DENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIV. . . . . . GANEKEIALMNALT
Template Known Secondary structure  T
B

BTTTS

B
TTGGGGGTSSSS
GGGTTGGG......T

GGG
S
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   65....70.........80.........90.........100.........110.........120.... .....130........
 
   108.110.........120 .........130.........140.........150.........160.........170...... ...180.
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Query Sequence  SAFFYLFNLFAGR. . . RADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELLPEGQFKYHVDFEHLHI. . . GEETG
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Template Sequence  VNLHLLMLSFFKPTPKRYKILLEAKAFPS. . DHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIA
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SSS
TT

..TT




TT
SS

GGG
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   139140.........150.........160....... ..170.........180.........190.........200.........210......
 
   182.......190.........200.........210.........220.........230.........240.........250.........260.
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Query Sequence  MICVSRPTNPTGNVITDEELLKLDALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIII
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Template Sequence  VILFSGVHFYTGQHFN. . . IPAITKAGQAKGCYVGFDLAHAV. . . . GNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAF
Template Known Secondary structure  SB
TTT
BB

...TT

TTTT....TTS


T


SSSTT


TT


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   217..220.........230.. .......240.........250..... ....260.........270.........280.........
 
   262.......270....... ..280.........290.........300.........310......
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Query Sequence  ANEKIITAITNMNGII. . . . . . . . . . . . . . . . . . . . . . . . . SLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQE
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Template Sequence  IHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLE. . IFKQATMKALRKKSVLLTGY
Template Known Secondary structure 
GGGTTTS

SS

GGGB
TT

S


B
SSGGGG

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   290.........300.........310.........320.........330.........340....... ..350.........360.......
 
   317..320.........330....... ..340.........350.........360.........370.........380.........390..
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Query Sequence  TIAIIRRYLPENRCLIHKPEG. . . . AIFLWLWFKDLPITTKQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
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Template Sequence  LEYLIKHN. . YGVVNIITPSHVEERGCQLTITFSV. . . PNKDVFQELEKRGVVCDK. . . . . . . . . . . . . RNPNGIRVAPV
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S
SSGGGB
S


...TT

TTT
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   368.370..... ....380.........390.........400 .........410........ .420.........
 
   393......400.........410
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Query Sequence  . . . PEPEKIEAGVKILAEEIE
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Template Sequence  PLYNSFHDVYKFTNLLTSILD
Template Known Secondary structure  TTT

T
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   439440.........450.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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