|   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
Query Sequence |   |
N | F | S | I | I | A | H | I | D | H | G | K | S | T | L | S | D | R | I | I | Q | I | C | G | G | L | S | D | R | E | M | E | A | Q | V | L | D | S | M | D | L | E | R | E | R | G | I | T | I | K | A | Q | S | V | T | L | D | Y | K | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | D |
Query Conservation |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |
|   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
  |
|
|
|
|
|   |
|
|
|
|
|
|
|
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | I | G | M | V | G | H | V | D | H | G | K | T | T | L | T | K | A | L | T | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | W | T | D | S | E | E | L | R | R | G | I | T | I | K | I | G | F | A | D | A | E | I | R | R | C | P | N | C | G | R | Y | S | T | S | P | V | C | P | Y | C | G | H | E | T |
Template Known Secondary structure |   |
 |  |  |  |  | S | S | T | T | S | S |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| T | T | S | S |
| S | S | S |
|
|  |  |  |  |  |  |  |  |  |
| T | T | T |
|
|  |  | S | S | S | B |
| T | T | T |
|
| B |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
  |
  |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | |
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | |
. | . | . | . | 130 | . | . | . | . | . | . | . | . | |
. | 140 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
G | E | T | Y | Q | L | N | F | I | D | T | P | G | H | V | D | F | S | Y | E | V | S | R | S | L | A | A | C | E | G | A | L | L | V | V | D | A | G | Q | G | V | . |
E | A | Q | T | L | A | N | C | Y | T | A | M | E | M | D | L | E | . |
V | V | P | V | L | N | K | I | D | L | P | A | A | . |
D | P | E | R | V | A |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|   |   |
|
| . |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|
| . |   |
|
|
|
|
|
|
|
|   |   |   |
| . |
|   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | F | V | R | R | V | S | F | I | D | A | P | G | H | E | A | L | M | T | T | M | L | A | G | A | S | L | M | D | G | A | I | L | V | I | A | A | N | E | P | C | P | R | P | Q | T | R | E | H | L | M | A | L | Q | I | I | G | Q | K | N | I | I | I | A | Q | N | K | I | E | L | V | D | K | E | K | A | L | E | N | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
| S |  |  |  |  |  |  |  | T | T | S |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |
| G | G | G | S |
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
145 | . | . | . | . | 150 | . | |
|
|
. | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 210 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | E | I | E | D | I | V | . |
. |
. |
G | I | D | A | T | D | A | V | R | C | S | A | K | T | G | V | G | V | Q | D | V | L | E | R | L | V | R | D | I | P | P | P | E | G | D | P | E | G | P | L | Q | A | L | I | I | D | S | W | F | D | N | Y | . |
. |
. |
. |
. |
L | G | V | V | S | L | I | R | I | K | N | G | T |
Query Conservation |   |
  |
|
|   |   |   |   | . | . | . |
|   |   |   |   |   |
|
|   |   |
|
|
|   |
|   |
|
|   |   |
|
|
|   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |   |
|   |   | . | . | . | . | . |   |
|   |
|   |   |   |
|
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|   |   |
|   |
Template Sequence |   |
R | Q | I | K | E | F | I | E | G | T | V | A | E | N | A | P | I | I | P | I | S | A | L | H | G | A | N | I | D | V | L | V | K | A | I | E | D | F | I | P | T | P | K | R | D | P | N | K | P | P | K | M | L | V | L | R | S | F | D | V | N | K | P | G | E | K | L | V | G | G | V | L | G | G | S | I | V | Q | G | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | S | T | T | T | T |
|
|  |  |  |
| B | T | T | T | T | B | T |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
|
| T | T | S |
|
|  |  |  |  |  |  |  |  |
|
| S |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  | . | . | . |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | K | G | D | K | V | K | V | M | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | G | Q | T | Y | N | A | D | R | L | G | I | F | T | P | K | Q | V | D | R | T | E | L | K | C | G | E | V | G | W | L | V | C | A | . |
. |
. |
I | K | D | I | H | G | A | P | V | G | D | T | L | T | L | A | R | N | P |
Query Conservation |   |
|
|   |
|
|   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |   | . | . | . |   |   |   |
|   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   | . | . | . |   |   |   |   |
|   |   |
|   |
|
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |
Template Sequence |   |
L | K | V | G | D | E | I | E | I | R | P | G | V | P | Y | E | E | H | G | R | I | K | Y | E | P | I | T | T | E | I | V | S | L | Q | A | . |
. |
. |
G | G | Q | F | V | E | E | A | Y | P | G | G | L | V | G | V | G | T | K | L | D | P | Y | L | T | K | G | D | L | M | A | G | N | V | V | G | K | P | G | K | L |
Template Known Secondary structure |   |
 |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | T | T |  |  |
| S |  |  |
| S | S | S |
|  |  |  |  |  | S | S |
| G | G | G | T | G | G | G | T | T | T | T |
|  |  |  |
| T | T |
| S |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|  |  |  |
|  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
243 | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | |
|
|
. | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
  |