|   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | V | K | Q | T | Q | M | I | G | L | S | P | G | M | T | Q | L | K | K | E | I | E | I | V | A | A | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | L | N | V | L | I | S | G | E | T | G | T | G | K | E | L | V | A | K | A | I | H | E | A | S | P | R | A | V | N | P | L | V | Y | L | N | C | A | A | L | P |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   | . | . |
Template Sequence |   |
P | Q | V | T | W | E | D | I | G | G | L | E | D | V | K | R | E | L | Q | E | L | V | Q | Y | P | V | E | H | P | D | K | F | L | K | F | G | M | T | P | S | K | G | V | L | F | Y | G | P | P | G | C | G | K | T | L | L | A | K | A | I | A | N | E | C | Q | A | N | . |
. |
. |
F | I | S | I | K | G | P | E | . |
. |
Template Known Secondary structure |   |
|
|
| S |
| S | S |
| S | S | S | S |
|
|
|
|  |  |  |  |  | T |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  | B |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  | . | . | . |  |  |  |  |
|  |  |  | . | . |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |  |  |  |  |
|
|  |  | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
472 | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | |
|
|
. | 540 | . | . | . | . | . | . | |
|
  |
  |   |
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | S | V | A | E | S | E | L | F | G | H | V | K | G | A | F | T | G | A | I | S | N | R | S | G | K | F | E | M | A | D | N | G | T | L | F | L | D | E | I | G | E | L | S | L | A | L | Q | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | L | L | R | V | L | Q | Y | G | D | I | Q | R | V | G | D | D | R | C | L | R |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
L | L | T | M | W | F | G | E | S | E | A | N | V | R | E | I | F | D | K | A | R | Q | A | A | P | C | V | L | F | F | D | E | L | D | S | I | A | K | A | R | G | G | N | I | G | D | G | G | G | A | A | D | R | V | I | N | Q | I | L | T | E | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . |  |  | T | S |
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  | S | S | G | G | G | T |
|
|  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
547 | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | |
|
|
. | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | V | R | V | L | A | A | T | N | R | D | L | R | . |
. |
. |
E | E | V | L | A | G | R | F | R | A | D | L | F | H | R | L | S | V | F | P | L | S | V | P | P | L | R | E | R | G | D | D | V | I | L | L | A | G | Y | F | C | E | Q | C | R | L | R | Q | G | L | S | R | V | V | L | S | A | G | A | R | N | L | L |
Query Conservation |   |
  |   |   |
|   |
|   |   |
|   |   |   |
|   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   | . | . | . | . | . | . | . |
|   |   |   |   |
|   |   |   |   |
|   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |   |   |   |   |   |
| . | . | . | . |   |   |
|
|   |   |
|
Template Sequence |   |
D | N | V | F | I | I | G | A | T | N | R | P | D | I | I | D | P | A | I | L | R | P | G | R | L | D | Q | L | . |
. |
. |
. |
. |
. |
. |
I | Y | I | P | L | P | D | E | K | S | R | V | A | . |
. |
. |
. |
. |
. |
. |
. |
I | L | K | A | N | L | R | K | S | D | V | D | L | . |
. |
. |
. |
E | F | L | A | K | M | T |
Template Known Secondary structure |   |
|
|
|  |  |  |  |
|
| B | S |
| T | T | T | S |
| G | G | G | S | S | T | T | S |  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  | T | T |
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
609 | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 640 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
650 | . | . | . | . | . | . | . | . | . | 660 | . | . | |
|
|
|
. | . | . | . | . | . | . |
  |
  |   |
396 | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | H | Y | S | F | P | G | N | V | R | E | L | E | H | A | I | H | R | A | V | V | L | A |
Query Conservation |   |
  |   |
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   | . | . | . | . |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|
Template Sequence |   |
N | G | F | . |
. |
. |
. |
S | G | A | D | L | T | E | I | C | Q | R | A | C | K | L | A |
Template Known Secondary structure |   |
| S | S | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
680 | . | . | |
|
|
|
. | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . |
  |