|   |
167 | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
|
|
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | S | Q | N | M | L | P | G | D | A | T | P | F | E | A | V | K | Q | T | Q | M | I | G | . |
. |
. |
L | S | P | G | M | T | Q | L | K | K | E | I | E | I | V | A | A | S | D | L | N | V | L | I | S | G | E | T | G | T | G | K | E | L | V | A | K | A | I | H | E | A | S | P | R | A | V | N | P | L | V | Y | L | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
| . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |
|   | . |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
S | H | V | K | G | L | G | L | D | E | S | G | L | A | K | Q | A | A | S | G | L | V | G | Q | E | N | A | R | E | A | C | G | V | I | V | E | L | I | K | S | K | K | M | A | G | R | A | V | L | L | A | G | P | P | G | T | G | K | T | A | L | A | L | A | I | A | Q | E | L | G | . |
S | K | V | P | F | C | P | M | V |
Template Known Secondary structure |   |
T | T |
|
| S |
|
| B |
| T | T | S |
| B |
| S |  |  | T | T |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T |
|  |  |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
| . | T | T | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | |
. | 90 | . | . | . | . | . | . | . |
  |
  |   |
244 | . | . | . | . | . | 250 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | A | A | L | P | E | S | . |
. |
. |
. |
. |
. |
. |
V | A | E | S | E | L | F | G | H | V | K | G | A | F | T | G | A | I | S | N | R | S | G | K | F | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | A | D | N | G | T | L | F | L | D | E | I | G | E | L | S | L |
Query Conservation |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | S | E | V | Y | S | T | E | I | K | K | T | E | V | L | M | E | N | F | R | R | A | I | G | L | R | I | K | E | T | K | K | K | E | I | I | Q | D | V | T | L | H | D | L | D | V | A | G | E | I | N | K | V | V | N | K | Y | I | D | Q | G | I | A | E | L | V | P | G | V | L | F | V | D | E | V | H | M | L | D | I |
Template Known Secondary structure |   |
G | G | G | G |
|
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |
|  |  |  |  |  |
| G | G | G |
| B |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
98 | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . |
  |
  |   |
294 | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | Q | A | K | L | L | R | V | L | Q | Y | G | D | I | Q | R | V | G | D | D | R | C | L | R | V | D | V | R | V | L | A | A | T | N | R | D | L | R | E | E | V | L | A | G | R | F | R | A | D | L | F | H | R | L | S | V | F | P | L | S | V | P | P | L | R | E | R | G | D | D | V | I | L | L | A | G | Y | F | C |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   | . | . |
Template Sequence |   |
E | C | F | T | Y | L | H | R | A | L | E | S | S | I | A | P | I | V | I | F | A | S | N | R | G | N | C | V | I | R | G | T | E | D | I | T | S | . |
. |
. |
. |
. |
. |
P | H | G | I | P | L | D | L | L | D | R | V | M | I | I | R | T | M | L | Y | T | P | Q | E | M | K | Q | I | I | K | I | R | A | Q | T | . |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | S | S | S |
|
|  |  |  |  |  |  |
|
| S |  |  |  |
| B | T | T | S | S |
|  |  | . | . | . | . | . | . |  | T | T |
|
|  |  |  |  | T | T |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | |
|
  |
  |   |
374 | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | |
|
|
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Q | C | R | L | R | Q | G | L | S | R | V | V | L | S | A | G | A | R | N | L | L | Q | H | Y | S | F | P | G | N | V | R | E | L | E | H | A | I | H | R | A | V | V | L | A | R | . |
. |
. |
A | T | R | S | G | D | E | V | I | L | E | A | Q | H | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |
|   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | G | I | N | I | S | E | E | A | L | N | H | L | G | E | I | G | T | K | T | T | L | R | Y | S | V | Q | L | L | T | P | A | N | L | L | A | K | I | N | G | K | D | S | I | E | K | E | H | V | E | E | I | S | E | L |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | T | T |
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S | B |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
382 | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . |
  |