|   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
R | T | R | V | L | I | L | G | V | N | G | F | I | G | N | H | L | T | E | R | L | L | R | E | D | H | Y | E | V | Y | G | L | D | I | G | S | D | A | I | S | R | F | L | N | H | . |
. |
. |
. |
. |
. |
. |
P | H | F | H | F | V | E | G | D | I | S | I | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |
|   |   |
|
|   |   |
| . |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | P | V | A | L | V | T | G | A | A | K | R | L | G | S | S | I | A | E | A | L | H | A | E | G | . |
Y | T | V | C | L | H | Y | H | R | S | A | A | D | A | S | T | L | A | A | T | L | N | A | R | R | P | N | S | A | I | T | V | Q | A | D | L | S | N | V | A | T | A | S | S | V | P | V | T | L | F | S | R | C | S |
Template Known Secondary structure |   |
|
|  |  |  |  | T | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . |
|  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|  |  |  |  |  |
|
|
| S | S | S |
| B |
|
|
|
|
| B |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | |
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
374 | . | . | . | . | . | 380 | . | |
|
|
. | . | . | . | . | . | . | . | 390 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 430 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | W | I | E | Y | H | V | K | . |
. |
. |
K | C | D | V | V | L | P | L | V | A | I | A | . |
. |
. |
. |
. |
. |
. |
T | P | I | E | Y | T | R | N | P | L | R | V | F | E | L | D | F | E | E | N | L | R | I | I | R | Y | C | V | K | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | K | R | I | I | F | P | S | T |
Query Conservation |   |
  |   |   |   |   |   |   |   | . | . | . |   |   |
|   |
|
|
|
|
|
|   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
A | L | V | D | A | C | Y | M | H | W | G | R | C | D | V | L | V | N | N | A | S | S | F | Y | P | T | P | L | L | R | D | K | E | S | L | E | V | A | A | A | D | L | F | G | S | N | A | I | A | P | Y | F | L | I | K | A | F | A | Q | R | V | A | D | T | R | A | E | Q | R | G | T | S | Y | S | I | V | N | M | V | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| S |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| G | G | G |
|
| S |
|
|  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
91 | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 |
  |
  |   |
433 | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | |
|
|
. | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | E | V | Y | G | M | C | S | D | K | Y | F | D | E | D | H | S | N | L | I | V | G | P | V | N | K | P | R | W | I | Y | S | V | S | K | Q | L | L | D | R | V | I | W | A | Y | G | E | K | . |
. |
. |
E | G | L | Q | F | T | L | F | R | P | F | N | W | M | G | P | R | L | D | N | L | N | A | A | R | I | G | S | S |
Query Conservation |   |
  |   |
|
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   | . | . | . |   |
|
|   |   |   |
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
A | M | T | S | Q | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | G | Y | T | M | Y | T | M | A | K | E | A | L | E | G | L | T | R | S | A | A | L | E | L | A | S | L | Q | I | R | V | N | G | V | S | P | G | L | S | V | L | P | D | D | M | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | T | S | S | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|  |  |  |  |  |  |  | S | S | B | S |
|
| S | S |
|
| . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
182 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
|
|
|
|
|
|
|
  |
  |   |
510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | I | T | Q | L | I | L | N | L | V | E | G | S | P | I | K | L | I | D | G | G | K | Q | K | R | C | F | T | D | I | R | D | G | I | E | A | L | Y | R | I | I | E | N | A | G | N | R | C | D | G | E | I | I | N | I | G | N | P |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |
|   |
|   |   |
|   |
|   |
|   |
|   |   |   |
|
|
|
|   |
|   |
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|
|
|
|
|   |   |
|   |   |
|   |
|   |   |
|   |   |
|
|
|   |   |
|   |
|
|
|
|
Template Sequence |   |
. |
. |
. |
F | S | V | Q | E | D | Y | R | R | K | V | P | L | . |
. |
. |
. |
. |
. |
. |
. |
Y | Q | R | N | S | S | A | E | E | V | S | D | V | V | I | F | L | C | S | P | K | A | K | Y | I | T | G | T | C | I | K | V | D | G | G |
Template Known Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  | T | T |
| T | T | . | . | . | . | . | . | . | . | T | T | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  | S | G | G | G | T | T |
|
| S |
|  |  |  |  | S | T | T |
Template Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
  |