|   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | |
. | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | |
|
|
|
|
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
R | T | R | V | L | I | L | G | V | N | G | F | I | G | N | H | L | T | E | R | L | L | R | E | D | H | Y | E | V | Y | G | L | D | I | G | S | D | A | I | S | R | F | L | N | . |
H | P | H | F | H | F | V | E | G | D | I | S | I | H | S | E | W | I | E | Y | H | V | K | . |
. |
. |
. |
. |
. |
K | C | D | V | V | L |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|
|
|
|
|   |
|
|
|   |
|
|
|   |   |
|   |   |   |
| . |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | R | G | V | I | V | T | G | G | G | H | G | I | G | K | Q | I | C | L | D | F | L | E | A | G | . |
D | K | V | C | F | I | D | I | D | E | K | R | S | A | D | F | A | K | E | R | P | N | L | F | Y | F | H | G | D | V | A | D | P | L | T | L | K | K | F | V | E | Y | A | M | E | K | L | Q | R | I | D | V | L | V |
Template Known Secondary structure |   |
|
|  |  |  |  |  | S | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . |
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
388 | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | L | V | A | I | A | T | P | I | E | Y | T | R | N | P | L | R | V | F | E | L | D | . |
. |
. |
. |
. |
. |
. |
F | E | E | N | L | R | I | I | R | Y | C | V | K | Y | R | K | R | I | I | F | P | S | T | S | E | V | Y | G | M | C | S | D | K | Y | F | D | E | D | H | S | N | L | I | V | G | P | V | N | K | P | R |
Query Conservation |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . |
|   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |
|
|
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
N | N | A | C | G | S | K | G | I | L | S | S | L | L | Y | E | E | F | D | Y | I | L | S | V | G | L | K | A | P | Y | E | L | S | R | L | C | R | D | E | L | I | K | N | K | G | R | I | I | N | I | A | S | T | R | A | F | Q | S | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | D | S |
Template Known Secondary structure |   |
 |
|
|
|
|
|
|
| G | G | G | T |
|
|  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
| G | G | G | T | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
|
Template Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
140 | . | . |
  |
  |   |
461 | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | |
|
. | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | I | Y | S | V | S | K | Q | L | L | D | R | V | I | W | A | Y | G | E | K | E | G | . |
. |
L | Q | F | T | L | F | R | P | F | N | W | M | G | P | R | L | D | N | L | N | A | A | R | I | G | S | S | R | A | I | T | Q | L | I | L | N | L | V | E | G | S | P | I | K | L | I | D | G | G | K | Q | K | R | C | F | T |
Query Conservation |   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
| . | . |
|   |   |   |
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|   |   |
|   |
|   |
|   |
|   |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
  |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|
|
|   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
Template Sequence |   |
E | A | Y | A | S | A | K | G | G | I | V | A | L | T | H | A | L | A | M | S | L | G | P | D | V | L | V | N | C | I | A | P | G | W | I | N | V | T | E | F | T | Q | E | D | C | A | A | I | P | A | G | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |
| S | B |
|
|
|
|
|
|  |  |  |  |  | T | S | T | T | S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
144 | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . |
  |
  |   |
539 | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | I | R | D | G | I | E | A | L | Y | R | I | I | E | N | A | G | N | R | C | D | G | E | I | I | N | I | G | N | P |
Query Conservation |   |
  |
|   |
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|   |   |   |   |   |
|   |
| . | . |   |   |   |
|
|
|   |   |
|   |
|
|
|
|
Template Sequence |   |
T | P | K | D | I | S | N | M | V | L | F | L | C | Q | . |
. |
Q | D | F | I | T | G | E | T | I | I | V | D | G | G |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  | T | . | . |
| S | S |
|
| S |
|  |  |  |  | S | T | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
201 | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
  |