|   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | Q | G | L | F | D | I | T | R | T | L | L | Q | Q | P | D | L | A | S | L | C | E | A | L | S | Q | L | V | K | R | S | A | L | A | D | N | A | A | I | V | L | W | Q | A | Q | T | Q | R | A | S | Y | Y | A | S | . |
. |
. |
. |
. |
. |
. |
. |
R | E | K | D | T | P | I | K | Y | E | D | E | T | V | L | A | H | G |
Query Conservation |   |
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |
|
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
S | S | R | L | L | E | L | V | K | D | I | S | S | H | L | D | V | T | A | L | C | H | K | I | F | L | H | I | H | G | L | I | S | A | D | R | Y | S | L | F | L | V | C | E | D | S | S | N | D | K | F | L | I | S | R | L | F | D | V | A | E | G | S | T | L | E | E | V | S | N | N | C | I | R | L | E | W | N | K | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| S |  |  |  |  |  |  |
|  |  |
| T | T | S |
|  |  |
|
| B | S |  |  |
|
| S | S | S |
|
| S |
| S | S |
| S |
|
| B |
|
|
| T | T |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
149 | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
  |
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
. | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | R | S | I | L | S | R | P | D | T | L | H | C | S | Y | E | E | F | C | E | T | W | P | Q | L | D | A | G | G | L | Y | P | K | F | G | H | Y | C | L | M | P | L | A | . |
A | E | G | H | I | F | G | G | C | E | F | I | R | Y | D | D | R | P | W | S | E | K | E | F | N | R | L | Q | T | F | T | Q | I | V | S |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   | . |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | V | G | H | V | A | A | L | G | E | P | L | N | I | K | D | A | Y | E | D | P | R | F | N | A | E | V | D | Q | I | T | G | Y | K | T | Q | S | I | L | C | M | P | I | K | N | H | R | E | E | V | V | G | V | A | Q | A | I | N | K | K | S | G | N | G | G | T | F | T | E | K | D | E | K | D | F | A | A | Y | L | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  | S |
| G | G | G |
| S | S |
|
| T |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  | S |
|
|
| S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | T | E | Q | I | Q | S | R | V | V | N | N | V | D | Y | E | L | L | C | R | E | R | D | N | F | R | I | L | V | A | I | T | N | A | V | L | S | R | L | D | M | D | E | L | V | S | E | V | A | K | E | I | H | Y | Y | F | D | I | D | D | I | S | I | V | L | R | S | H | R | K | N | K | L | N | I | Y | S | T | H |
Query Conservation |   |
  |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | C | G | I | V | L | H | N | A | Q | L | Y | E | T | S | L | L | E | N | K | R | . |
. |
. |
N | Q | V | L | L | D | L | A | S | L | I | F | E | E | Q | Q | S | L | E | V | I | L | K | K | I | A | A | T | I | I | S | F | M | Q | V | Q | K | C | T | I | F | I | V | D | E | D | C | S | D | S | F | S | S | V | F | H |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |  |  |
| S | S | S | S | S | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | |
|
|
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
  |
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | |
|
. | . | 310 | . | . | . | . | . | . | . | |
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . |
|
|  |  |  |  |  |  |  |  | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
Y | L | D | K | Q | H | P | A | H | E | Q | S | E | V | D | E | A | G | T | L | T | E | R | V | F | K | S | K | E | M | L | L | I | N | L | H | E | R | D | D | L | A | P | Y | E | R | M | L | F | D | T | W | G | N | Q | I | Q | T | L | C | L | L | P | L | M | S | . |
. |
G | D | T | M | L | G | V | L | K | L | . |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|
|   |   | . | . |   |   |   |   |
|
|
|
|   |
| . | . |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |
Template Sequence |   |
M | E | C | E | E | L | . |
. |
. |
. |
. |
. |
E | K | S | I | N | Y | M | Y | A | Q | Y | V | K | N | T | M | E | P | L | N | I | P | D | V | S | K | D | K | R | F | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
W | Q | C | I | R | S | L | L | C | T | P | I | K | N | G | K | K | N | K | V | I | G | V | C | Q | L | V | N |
Template Known Secondary structure |   |
 |  | T | T | T | B | . | . | . | . | . | . |
|
|
|
|
| T |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  | S |
| S | T | T |
| T | T | S |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
| S | S | S |
|
|  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
386 | . | . | . | 390 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 |
  |
  |   |
|
|
|
|
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
Predicted Secondary structure |   |
. | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
A | Q | C | E | E | K | V | F | T | T | T | N | L | N | L | L | R | Q | I | A | E | R | V | A | I | A | V | D | N | A | L | A | Y | Q | E | I | H | R | L | K | E | R | L |
Query Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |
|
|   |
|   |
|
|
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |
|
|   |
|
|   |
|   |
|   |   |   |
|   |   |
|   |
|
Template Sequence |   |
K | M | E | E | N | T | G | K | V | K | P | F | N | R | N | D | E | Q | F | L | E | A | F | V | I | F | C | G | L | G | I | Q | N | T | Q | M | Y | E | A | V | E | R | A | M | A | K | R |
Template Known Secondary structure |   |
|
|
| T | T | T |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
473 | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . |
  |