|   |
366 | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | T | E | Q | L | N | N | V | D | S | E | F | G | E | I | I | G | R | S | E | A | M | Y | S | V | L | K | Q | V | E | M | V | A | Q | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | S | T | V | L | I | L | G | E | T | G | T | G | K | E | L | I | A | R | A | I | H | N | L | S | G | R | N | N | R | R | M | V | K |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |   |   |   | . | . | . |   |   |   |   |
Template Sequence |   |
R | A | R | V | L | T | E | A | P | K | V | T | F | K | D | V | A | G | A | E | E | A | K | E | E | L | K | E | I | V | E | F | L | K | N | P | S | R | F | H | E | M | G | A | R | I | P | K | G | V | L | L | V | G | P | P | G | V | G | K | T | H | L | A | R | A | V | A | G | E | A | R | V | . |
. |
. |
P | F | I | T |
Template Known Secondary structure |   |
|
|  |  |  |
| S |
|
|
|
|
| T | T | S | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | T | T | T | T | S |
|
|
|
| S |  |  |  |  |  |
| S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | |
|
|
. | . | . | . |
  |
  |   |
436 | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | N | C | A | A | M | P | A | G | L | L | E | S | D | L | F | G | H | E | R | G | A | F | T | G | A | S | A | Q | R | I | G | R | F | E | L | A | D | K | S | S | L | F | L | D | E | V | G | D | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | L | E | L | Q | P | K | L | L | R | V | L | Q | E | Q | E | F | E | R |
Query Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
|   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
Template Sequence |   |
A | S | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
S | D | F | V | E | M | F | V | G | V | G | A | A | R | V | R | D | L | F | E | T | A | K | R | H | A | P | C | I | V | F | I | D | E | I | D | A | V | G | R | K | R | G | S | G | V | G | G | G | N | D | E | R | E | Q | T | L | N | Q | L | L | V | E | M | D | . |
. |
. |
Template Known Secondary structure |   |
 |  | G | . | . | . | . | . | . | . | . | . | G | G | G | T | S | S |
| T | T |  |  |  |  |  |  |  |  |  |  | T | T | S | T | T | S | S | S |
|  |  |  |  |  |
| G | G | G | T |
|
|
| S | S | S | S | T | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | . | . | . |
Template Predicted Secondary structure |   |
 |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
220 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | |
|
|
  |
  |   |
505 | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | S | N | K | I | I | Q | T | D | V | R | L | I | A | A | T | N | R | D | L | K | K | M | V | A | D | R | E | F | R | S | D | L | Y | Y | R | L | N | V | F | P | I | H | L | P | P | L | R | E | R | P | E | D | I | P | L | L | A | K | A | F | T | F | K | I | A | R | R | L | G | R | N | I | D | S | I | P | A | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   | . | . |   |   |
|
|   |
|
|   |
|   |   |
|
|   |   | . | . |   |   |   |   |   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
G | F | E | K | D | T | A | I | V | V | M | A | A | T | N | R | P | . |
. |
D | I | L | D | P | A | L | L | R | P | G | R | F | D | R | . |
. |
Q | I | A | I | D | A | P | D | V | K | G | R | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | I | L | R | I | H | A | R | G | K | P | L | A | E | D | V |
Template Known Secondary structure |   |
. | . | . | G |
|
| S | S |
|
|
|  |  |  |  |
|
| S |
| G | . | . | G | G | S |
| T | T | T | S | S | T | T | S | S |
|
| . | . |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | T | T | S | S | S |
|
|
|
| S | S |
Template Predicted Secondary structure |   |
. | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  | . | . |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
| . | . |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
288 | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | |
|
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
|
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . |
  |
  |   |
585 | . | . | . | . | 590 | . | . | . | . | . | . | |
. | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | L | R | T | L | S | N | M | E | W | P | G | . |
N | V | R | E | L | E | N | V | I | E | R | A | V | L | L | T |
Query Conservation |   |
|   |   |   |
|   |   |
|   |
|
|
| . |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   | . |
|   |
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|
Template Sequence |   |
D | L | A | L | L | A | K | R | . |
T | P | G | F | V | G | A | D | L | E | N | L | L | N | E | A | A | L | L | A |
Template Known Secondary structure |   |
T | T |  |  |  |  | T | T | . | S |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
349 | 350 | . | . | . | . | . | . | |
. | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . |
  |