|   |
405 | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | I | L | G | E | T | G | T | G | K | E | L | I | A | R | A | I | H | N | L | S | G | R | N | N | R | R | M | V | K | M | N | C | . |
. |
. |
. |
. |
. |
. |
A | A | M | P | A | G | L | L | E | S | D | L | F | G | H | E | R | G | A | F | T | G | A | S | A | Q | R | I | G | R | F | E | L | A | D | K | S | S | L |
Query Conservation |   |
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
| . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
Template Sequence |   |
Y | L | L | L | G | N | D | P | L | L | L | Q | E | S | Q | D | A | V | R | Q | V | A | A | A | Q | G | F | E | E | H | H | T | F | S | I | D | P | N | T | D | W | N | A | I | F | S | L | C | Q | A | M | S | L | F | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | R | Q | T | L |
Template Known Secondary structure |   |
 |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |
|
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 80 |
  |
  |   |
478 | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | L | D | E | V | G | D | M | P | L | E | L | Q | P | K | L | L | R | V | L | Q | E | Q | E | F | E | R | L | G | S | N | K | I | I | Q | T | D | V | R | L | I | A | A | T | N | R | D | L | K | K | M | V | A | D | R | E | F | R | S | D | L | Y | Y | R | L | N | V | F | P | I | H | L | P | P | L | R | E | R | P | E |
Query Conservation |   |
  |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | L | L | L | P | E | N | G | P | N | A | A | I | N | E | Q | L | L | T | L | T | G | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | D | D | L | L | L | I | V | R | G | N | K | L | . |
. |
. |
. |
. |
S | K | A | Q | E | N | A | A | W | F | T | A | L | A | N | R | S | V | Q | V | T | C | Q | T | P | E | Q | A |
Template Known Secondary structure |   |
 |  |  |
|
| S | S |
| S |
| T | T |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . | . | . | . | . | . | . | . |
| S | S |
|  |  |  |  |  |  | S |
|
| . | . | . | . | . |
| T | T | T | T | T | S |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |
|
|
|
| T | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 110 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
  |
  |   |
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | |
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
D | I | P | L | L | A | K | A | F | T | F | K | I | A | R | R | L | G | R | N | I | D | S | I | P | A | E | T | L | R | T | L | S | N | M | E | W | P | G | N | V | R | E | L | E | N | V | I | E | R | A | V | L | L | T | R | G | N | V | L | Q | L | S | L | P | D | I | V | L | P | E | P | E | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |
| . | . | . | . | . | . | . |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   | . |   |   |
|   |   |   |
|   |   |
|
|
|
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
Q | L | P | R | W | V | A | A | R | A | K | Q | L | N | . |
. |
. |
. |
. |
. |
. |
L | E | L | D | D | A | A | N | Q | V | L | C | Y | C | Y | . |
E | G | N | L | L | A | L | A | Q | A | L | E | R | L | S | L | L | W | P | D | G | K | L | T | L | P | R | V | E | Q | A | V | N | D | A | A | H | F | T | P | F | H | W |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . | . |
|  |  |
|  |  |  |  |  |  |  |  |  | S | S | . | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | |
. | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
631 | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | P | P | A | A | T | V | V | A | L | E | G | E | D | E | Y | Q | L | I | V | R | V | L | K | E | T | N | G | V | V | A | G | P | K | G | A | A | Q | R | L | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | R | T | T |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
V | D | A | L | L | M | G | K | S | K | R | A | L | H | I | L | Q | Q | L | R | L | E | G | S | E | P | V | I | L | L | R | T | L | Q | R | E | L | L | L | L | V | N | L | K | R | Q | S | A | H | T | P | L | R | A | L | F | D | K | H | R | V | W | Q | N | R | R | G | M | M | G | E | A | L | N | R | L | S | Q | T | Q |
Template Known Secondary structure |   |
 |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  | T | S | S | T | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S | S | S |
|  |  |  |  |  |  |  |  | T |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
218 | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
  |
  |   |
677 | . | . | 680 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | S | R | M | K | R | L |
Query Conservation |   |
|   |
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |
|
Template Sequence |   |
L | R | Q | A | V | Q | L | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
  |   |
298 | . | 300 | . | . | . | . | . |
  |