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Job DescriptionQ46925
Confidence100.00%DateThu Jan 5 12:35:54 GMT 2012
Rank5Aligned Residues366
% Identity15%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   17..20.........30.........40.........50.........60.........70.........80.........90......
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Query Sequence  QDAGVYLDSAATALKPEAVVEATQQFYSLSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTTESINM
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Template Sequence  DENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGA. NEKEIALMNALTVNLHL
Template Known Secondary structure  T
B

BTTTS

B
TTGGGGGTSSSS
GGGTTGGGT
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GGG
S
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   65....70.........80.........90.........100.........110.........120...... ...130.........140...
 
   97..100.........110.........120.........130...... ...140.........150....... ..160........
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Query Sequence  VAQCYARPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAK. . . . . VVKLPLNAQRLPDVDLLPELI. . . TPRSRILALGQ
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Template Sequence  LMLSFFKP. TPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSG
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SSS
TT

TT




TT
SS

GGGS
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   144.....150. ........160.........170.........180.........190.........200.........210.........220..
 
   169170.........180.........190.........200.........210.........220.... .....230.........240......
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Query Sequence  MSNVTGGCPDLARAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAFSGHKLY. . GPTGIGVLYGKSELLEAMSPWL
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Template Sequence  VHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPAL
Template Known Secondary structure  B
TTT
BB

TT

TTTTTTS


T


SSSTT


TT



GGGTTTS

SS
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   223......230.........240.........250.........260.........270.........280.........290.........300..
 
   247..250... ......260.........270.........280.........290.........300.........310.. .......320.
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Query Sequence  GGGKMVH. . . . EVSFDGFTTQSAPWKLEAGTPNVAGVIGLSAALEWLADYDINQAESWSRSLATLAEDAL. AKRPGFRSF
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Template Sequence  VGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGVVNII
Template Known Secondary structure 

GGGB
TT

S


B
SSGGGG

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   303......310.........320.........330.........340.........350.........360.........370.........380..
 
   322... ....330.........340.........350.........360.........370...... ...380.........390......
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Query Sequence  RCQD. . . . SSLLAFDFAGVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASF. APYNTKSDVDALVNAVDRAL
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Template Sequence  TPSHVEERGCQLTITFSV. PNKDVFQELEKRGVVCD. . . . . . . . . . . . KRNPNGIRVAPVPLYNSFHDVYKFTNLLTSIL
Template Known Secondary structure  S
SSGGGB
S


.TT

TTT
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TTT

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   392.......400......... 410.........420...... ...430.........440.........450........
 
   397
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Query Sequence  E
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Template Conservation 
Template Sequence  D
Template Known Secondary structure  T
Template Predicted Secondary structure 
Template SS confidence 
   459
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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