|   |
66 | . | . | . | 70 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | A | R | E | K | V | A | Q | L | L | N | A | . |
. |
. |
. |
. |
. |
. |
P | D | D | K | T | I | V | W | T | R | G | T | T | E | S | I | N | M | V | A | Q | C | Y | A | R | P | R | L | Q | P | G | D | E | I | I | V | S | V | A | E | H | H | A | N | L | V | P | W | L | M | V | A | Q | Q | T | G | A | K | V | V |
Query Conservation |   |
  |   |   |
|   |   |
|
|   |   |   |
|   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |
|
|   |
|   |   |   |   |   | . | . | . | . |   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |
|   |
Template Sequence |   |
E | E | L | R | D | L | W | Q | Q | K | M | L | R | D | N | P | E | L | S | I | D | N | M | S | R | P | I | V | T | N | A | L | T | H | G | L | S | L | V | G | D | L | F | . |
. |
. |
. |
V | N | Q | D | D | T | I | L | L | P | E | H | N | W | G | N | Y | K | L | V | F | N | T | . |
. |
. |
R | N | G | A | N | L | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
| G | G | G | B |
|
|
|  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
| T | T |
|  |  |  |  |  | S | S |
|
| T |  |  |  |  |  |  | T | T | . | . | . | T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | |
|
|
|
. | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | |
|
|
. | . | . | . | . | 160 | . |
  |
  |   |
139 | 140 | . | . | |
. | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | L | P | L | . |
N | A | Q | R | L | P | D | V | D | L | L | P | E | L | I | T | P | R | S | R | . |
. |
. |
I | L | A | L | G | Q | M | S | N | V | T | G | G | C | P | D | L | A | R | A | I | T | F | A | H | S | . |
. |
. |
. |
. |
. |
. |
. |
A | G | M | V | V | M | V | D | G | A | Q | G | A | V | H | F | P | A |
Query Conservation |   |
  |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|
|   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |
| . | . | . | . |   |   |   |
Template Sequence |   |
T | Y | P | I | F | D | K | D | G | H | Y | T | T | D | S | L | V | E | A | L | Q | S | Y | N | K | D | K | V | I | M | I | L | N | Y | P | N | N | P | T | G | Y | T | P | T | H | K | E | V | T | T | I | V | E | A | I | K | A | L | A | N | K | G | T | K | V | I | A | V | V | D | D | A | Y | . |
. |
. |
. |
Y | G | L |
Template Known Secondary structure |   |
 |  |
|
| B |
| T | T | S |
| B |
| S |  |  |  |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  |
| S | S |
| T | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
| T | T | . | . | . | . | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
|
|
. | . | . |
  |
  |   |
207 | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | V | Q | Q | L | D | I | D | F | Y | A | F | S | G | H | K | L | Y | G | P | T | G | I | G | V | L | Y | G | K | S | E | L | L | E | A | M | S | P | W | L | G | G | G | K | M | V | H | E | V | S | F | D | G | F | T | T | Q | S | A | P | . |
. |
. |
. |
. |
. |
W | K | L | E | A | G | T | P | N | V | A | G | V | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
F | Y | E | D | V | Y | T | Q | S | L | F | T | A | L | T | N | L | H | S | N | A | I | L | P | I | R | L | D | G | A | T | K | E | F | F | A | W | G | F | R | V | G | F | M | T | F | G | T | S | D | Q | T | T | K | E | V | L | E | A | K | V | K | G | L | I | R | S | N | I | S | S | G | P | L | P | T | Q | S | A | V |
Template Known Secondary structure |   |
B |
| S | S |
|
|
| S |
|  |  |  |  |  |  | T | T |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G |
|
|  |  |  |  |  | B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S | S |
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
  |
  |   |
281 | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
|
. | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
. | . | . | . | 350 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | L | S | A | A | L | E | W | L | A | D | Y | D | I | N | Q | A | E | S | W | S | R | S | L | A | T | L | A | E | D | A | L | A | K | . |
. |
. |
R | P | G | F | R | S | F | R | C | Q | D | S | S | L | L | A | F | D | F | A | G | V | H | H | S | D | M | V | T | L | L | . |
A | E | Y | G | I | A | L | R | A | G | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| . |   |   |   |
|
|   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|   |
|   |   |
Template Sequence |   |
K | H | V | L | K | N | N | K | Q | F | D | K | E | I | E | Q | N | I | Q | T | L | K | E | R | Y | E | V | T | K | E | V | V | Y | A | D | Q | Y | H | S | H | W | Q | A | Y | D | F | N | S | G | Y | F | M | A | I | K | V | H | D | V | D | P | E | A | L | R | K | H | L | I | D | K | Y | S | I | G | V | I | A | L | N |
Template Known Secondary structure |   |
 |  |  | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G | T | T | T |  |  |  |
|
|
|
| B | S | S |  |  |  |  |  |  | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|  |  |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . |
  |
  |   |
357 | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | C | A | Q | P | L | L | A | E | L | G | V | T | G | T | L | R | A | S | F | A | P | Y | N | T | K | S | D | V | D | A | L | V | N | A | V | D | R | A | L | E | L | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |   |
|   |   |   |
|   |   |
|
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|
|   |   | . |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|
Template Sequence |   |
A | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | I | R | I | A | F | S | . |
C | V | E | K | D | D | I | P | H | V | F | D | S | I | A | K | A | I | D | D | L |
Template Known Secondary structure |   |
S | S | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | G | G | . | G | S |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
398 | . | |
|
|
|
|
|
|
|
|
|
|
|
400 | . | . | . | . | . | . | |
. | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . |
  |