Job Description Q46925 Confidence 100.00% Date Thu Jan 5 12:35:54 GMT 2012 Rank 6 Aligned Residues 381 % Identity 16% Template c2hzpA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase Resolution 2.00 Å

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		1	.	.	.	.	.		.	.	.	10	.	.	.	.																.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.
Predicted Secondary structure								.									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence								.									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		M	N	V	F	N	P	.	A	Q	F	R	A	Q	F	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	L	Q	D	A	G	V	Y	L	D	S	A	A	T	A	L	K	P	E	A	V	V	E	A	T	Q	Q	F	Y	S	L	S	A	G	N	V	H	R	S	Q	F	A	E	A	Q	R	L	T	A	R
Query Conservation								.									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence								.					.				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation													.
Template Sequence		L	D	E	E	D	K	L	R	H	F	R	.	E	F	Y	I	P	K	I	Q	D	L	P	P	V	D	L	S	L	V	N	K	D	E	N	A	I	Y	F	L	G	N	S	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G
Template Known Secondary structure							T	T	G	G	G	G	.			B			B	G	G	G	S	T	T			G	G	G	S		T	T		B					B	T	T	T	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T
Template Predicted Secondary structure													.
Template SS confidence
		33	.	.	.	.	.	.	40	.	.	.		.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.
		65	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.						.	.	.
Predicted Secondary structure																																																																										.	.	.	.	.
Query SS confidence																																																																										.	.	.	.	.
Query Sequence		Y	E	A	A	R	E	K	V	A	Q	L	L	N	A	P	D	D	K	T	I	V	W	T	R	G	T	T	E	S	I	N	M	V	A	Q	C	Y	A	R	P	R	L	Q	P	G	D	E	I	I	V	S	V	A	E	H	H	A	N	L	V	P	W	L	M	V	A	Q	Q	T	G	A	K	.	.	.	.	.	V	V	K
Query Conservation																																																																										.	.	.	.	.
Alig confidence																.																										.																																.	.	.	.	.
Template Conservation																.																										.
Template Sequence		D	E	S	I	V	G	L	M	K	D	I	V	G	A	.	N	E	K	E	I	A	L	M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F	K	P	.	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I
Template Known Secondary structure		T	T	T	T	G	G	G	G					T		.		G	G	G					S																	.		S	S	S							T	T																T	T
Template Predicted Secondary structure																.																										.
Template SS confidence
		113	.	.	.	.	.	.	120	.	.	.	.	.	.		.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.		.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190
		140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.				.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.
Predicted Secondary structure																					.	.	.
Query SS confidence																					.	.	.
Query Sequence		L	P	L	N	A	Q	R	L	P	D	V	D	L	L	P	E	L	I	T	.	.	.	P	R	S	R	I	L	A	L	G	Q	M	S	N	V	T	G	G	C	P	D	L	A	R	A	I	T	F	A	H	S	A	G	M	V	V	M	V	D	G	A	Q	G	A	V	H	F	P	A	D	V	Q	Q	L	D	I	D	F	Y
Query Conservation																					.	.	.
Alig confidence																					.	.	.
Template Conservation
Template Sequence		K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	V	E	L	Y	L	H	D	W	G	V	D	F	A
Template Known Secondary structure					T	T		S	S														G	G	G								S	B		T	T	T		B	B													T	T								T	T	T	T	T	T	S								T
Template Predicted Secondary structure
Template SS confidence
		191	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270
		217	.	.	220	.	.	.	.			.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.					.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
Predicted Secondary structure										.	.																																	.	.	.	.
Query SS confidence										.	.																																	.	.	.	.
Query Sequence		A	F	S	G	H	K	L	Y	.	.	G	P	T	G	I	G	V	L	Y	G	K	S	E	L	L	E	A	M	S	P	W	L	G	G	G	K	M	V	H	E	V	S	.	.	.	.	F	D	G	F	T	T	Q	S	A	P	W	K	L	E	A	G	T	P	N	V	A	G	V	I	G	L	S	A	A	L	E	W	L	A
Query Conservation										.	.																																	.	.	.	.
Alig confidence										.	.																																	.	.	.	.
Template Conservation
Template Sequence		C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K
Template Known Secondary structure					S	S	S	T	T				T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		271	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
		291	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.			.	.	.	.	320	.	.	.	.	.					.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.
Predicted Secondary structure																											.	.											.	.	.	.
Query SS confidence																											.	.											.	.	.	.
Query Sequence		D	Y	D	I	N	Q	A	E	S	W	S	R	S	L	A	T	L	A	E	D	A	L	A	K	R	.	.	P	G	F	R	S	F	R	C	Q	D	.	.	.	.	S	S	L	L	A	F	D	F	A	G	V	H	H	S	D	M	V	T	L	L	A	E	Y	G	I	A	L	R	A	G	Q	H	C	A	Q	P	L	L	A
Query Conservation																											.	.											.	.	.	.
Alig confidence																											.	.											.	.	.	.											.																		.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																					.																		.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	K	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	.	P	N	K	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure																																			S		S	S	G	G	G	B		S									.	T	T									T	T	T					.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																					.																		.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.		.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.
		365	.	.	.	.	370	.	.	.	.	.	.		.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.
Predicted Secondary structure														.
Query SS confidence														.
Query Sequence		E	L	G	V	T	G	T	L	R	A	S	F	.	A	P	Y	N	T	K	S	D	V	D	A	L	V	N	A	V	D	R	A	L	E
Query Conservation														.
Alig confidence		.												.
Template Conservation		.
Template Sequence		.	K	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L	L	T	S	I	L	D
Template Known Secondary structure		.			T	T	T					B			T	T	T																		T
Template Predicted Secondary structure		.
Template SS confidence
			427	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.