|   |
38 | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | W | V | L | M | D | Y | T | T | G | Q | I | L | T | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | E | H | Q | Q | R | N | P | A | S | L | T | K | L | M | T | G | Y | V | V | D | R | A | I | D | S | H | R | I | T | P | D | D | I | V | T | V | G | R | D | A | W |
Query Conservation |   |
|
|
|
|   |
|   |   |
|
|   |
|
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|   |
|   |   |
|
|   |
|
|
|   |   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |
|
|
|
| . | . | . |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
Template Sequence |   |
T | A | T | L | V | S | A | K | T | G | E | I | L | A | T | T | Q | R | P | T | F | D | A | D | T | K | E | G | I | T | E | D | F | V | W | R | D | I | L | Y | Q | S | N | Y | E | P | G | S | T | M | K | V | M | M | L | A | A | A | I | D | . |
. |
. |
N | N | T | F | P | G | G | E | V | F | N | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T |
| B |  |  |  |  |  |  |  | S |
|
| B | T | T | T | T | B | T |
|
| S | S |
|
|
|
|
| T | T | T | S |
|
| B |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  |  | . | . | . |  | T |
|
|
| T | T |
|  |  |  | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | |
|
|
350 | . | . | . | . | . | . | . | . | . | 360 | |
|
|
|
|
|
  |
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | K | D | N | P | V | F | V | G | S | S | L | M | F | L | K | E | . |
. |
. |
. |
. |
. |
. |
G | D | R | V | S | V | R | D | L | S | R | G | L | I | V | D | S | G | N | D | A | C | V | A | L | A | D | Y | I | A | G | G | Q | R | Q | F | V | E | M | M | N | N | Y | A | E | K | L | H | L | K | D | T | H | F | E | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   | . | . | . | . | . | . | . |
|   |   |   |
|
|   |
|
|
|   |
|   |
|
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |
| . | . | . | . |
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |
| . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . |
Template Sequence |   |
. |
. |
S | S | E | L | K | I | A | D | A | T | I | R | D | W | D | V | N | E | G | L | T | G | G | R | M | M | T | F | S | Q | G | . |
. |
. |
. |
F | A | H | S | S | N | V | G | M | T | L | L | E | Q | K | M | G | . |
. |
. |
. |
. |
. |
D | A | T | W | L | D | Y | L | N | R | F | K | F | G | V | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . |
| S |
|  |  |  | T | T |  |  |  |
|
|  |  |  |  | T | T | S |
| S |
|
|  |  |  |  |  |  |  | . | . | . | . |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T | T | T | S | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . |
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
361 | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | |
|
|
|
. | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | |
|
|
|
|
  |
  |   |
169 | 170 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
V | H | G | L | D | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | H | S | S | A | Y | D | L | A | V | L | S | R | A | I | I | H | G | E | P | E | F | Y | H | M | Y | S | E | K | S | L | T | W | N | G | I | T | Q | Q | N | R | N | G | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|   |
| . |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | T | R | F | G | L | T | D | E | Y | A | G | Q | L | P | A | D | N | I | V | N | I | A | M | S | A | F | G | Q | G | I | S | V | T | Q | T | Q | M | L | R | A | F | T | A | I | A | N | D | G | . |
V | M | L | E | P | K | F | I | S | A | L | Y | D | P | N | D | Q | S | V | R | K | S | Q | K | E | I | V | G | N | P |
Template Known Secondary structure |   |
|
|
|
| S |
| S | S |
|
|
|
| B |
|
|
| S | S |  |  |  |  |  |  |  | T | T | T |
| S |
| B | B |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | . |
|  |  |
|
| B |
|
|
|  |  |  |  | T | T | T | T |  |  |  |  |
|
|
|
|  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
424 | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | |
. | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | L | W | D | K | T | M | N | V | D | G | L | K | T | G | H | T | S | G | A | G | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | L | I | A | S | A | V | D | G | Q | R | R |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |   |
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |
Template Sequence |   |
V | S | K | E | A | A | S | V | T | R | D | H | M | V | M | V | G | T | D | P | T | Y | G | T | M | Y | N | H | S | T | G | K | A | T | V | N | V | P | G | Q | N | V | A | L | K | S | G | T | A | E | I | A | D | E | K | N | G | G | Y | L | T | G | S | T | N | N | I | F | S | V | V | S | M | H | P | A | E | N | P | D |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | T |
| T | T | B |
| T | T | T | S | S | B | S | S |
| B | T | T | B |
|
|  |  |  |  |  |  |  |  |
| B |
| T | T | T | S | S | B |
|
| S | S | S | S |  |  |  |  |  |  |  |  |  | S | T | T | S |
| S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
503 | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . |
  |
  |   |
254 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
Query Sequence |   |
L | I | A | V | V | M |
Query Conservation |   |
  |
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
Template Sequence |   |
F | I | L | Y | V | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
  |   |
583 | . | . | . | . | . |
  |