|   |
33 | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | I | H | A | G | S | W | V | L | M | D | Y | T | T | G | Q | I | L | T | A | G | N | E | H | Q | Q | R | N | P | A | S | L | T | K | L | M | T | G | Y | V | V | D | R | A | I | D | S | H | R | I | T | P | D | D | I | V | T | V | G | R | D | A | W | A | K | D | N | P | V | F | V | G | S | S | L | M | F | L | K | E |
Query Conservation |   |
  |
|   |
|   |
|
|
|
|   |
|   |   |
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|
|   |   |   |
|   |   |
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |
|   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   | . | . | . | . | . | . |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
D | V | S | A | K | S | A | I | I | I | D | G | A | S | G | R | V | L | Y | A | K | D | E | H | Q | K | R | R | I | A | S | I | T | K | I | X | T | A | V | L | A | I | E | . |
. |
. |
. |
. |
S | G | K | X | D | Q | T | V | T | V | S | A | N | A | V | R | T | . |
. |
. |
. |
. |
. |
E | G | S | A | I | Y | L | T | E |
Template Known Secondary structure |   |
|
| S |
| S |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  | S | T | T |
|
| B |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | T | T |
| T | T | S |  |  |  |
|
|  |  |  |  | T |
| . | . | . | . | . | . |
| S | S |
|
|
|
|
| T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
90 | . | . | . | . | . | . | . | . |
  |
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | |
. | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
| . |
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | D | R | V | S | V | R | D | L | S | R | G | L | I | V | D | S | G | N | D | A | C | V | A | L | A | D | Y | I | A | G | G | Q | R | Q | F | V | E | M | M | N | N | Y | A | E | K | L | H | L | K | D | T | H | F | E | T | V | H | G | L | D | A | . |
P | G | Q | H | S | S | A | Y | D | L | A | V | L | S | R | A | I |
Query Conservation |   |
|   |   |   |
|
|   |
|
|
|   |
|   |
|
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |
|
|   |   | . |   |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|
|   |
|
|
|   |   |   |
|
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |
|
|
|   |   |   |
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |
Template Sequence |   |
G | Q | K | V | K | L | K | D | L | V | Y | G | L | X | L | R | S | G | N | D | A | A | V | A | I | A | E | H | V | G | G | S | L | D | G | F | V | Y | X | X | N | Q | K | A | E | Q | L | G | X | K | N | T | R | F | Q | N | P | H | G | L | D | D | H | E | N | H | Y | S | T | A | Y | D | X | A | I | L | T | K | Y | A |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |
| B |
| S | S | S | S |
|
| S |
| S | S | S |
| B | B |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
99 | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . |
  |
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
. | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | H | G | E | P | E | F | Y | H | M | Y | S | E | K | S | L | T | W | N | . |
. |
G | I | T | Q | Q | N | R | N | G | L | L | W | D | K | T | M | N | V | D | G | L | K | T | G | H | T | S | G | A | G | F | N | L | I | A | S | A | V | D | G | Q | R | R | L | I | A | V | V | M | G | A | D | S | A | K | G | R | E | E |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
Template Conservation |   |
  |   | . |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |
|   |   |
|   |
|
|
|   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|
|
|   |   |   | . | . | . |
|   |   |
Template Sequence |   |
X | K | . |
L | K | D | Y | Q | K | I | S | G | T | K | I | Y | K | A | E | T | X | E | S | V | W | K | N | K | N | K | L | L | T | X | L | Y | P | Y | S | T | G | G | K | T | G | Y | T | K | L | A | K | R | T | L | V | S | T | A | S | K | D | G | I | D | L | I | A | V | T | I | N | D | P | N | . |
. |
. |
D | W | D |
Template Known Secondary structure |   |
T | T | . | S |  |  |  |  |  |  |  | T |
| S |  |  |  |
| S | S | S | S |
|  |  |  |
| S |
|  |  |  |  | T | T |
| T | T |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | S |
| T | T | . | . | . |  |  |  |
Template Predicted Secondary structure |   |
 |
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
179 | 180 | |
. | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | |
|
|
. | . | . |
  |
  |   |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | R | K | L | L | R | W | G | Q | Q | N | F | T | T | V | Q | I | L | H | R | G | K | K | V | G | T | E | R | I | W | Y | G | D | K | E | N | I | D | L | G | T | E | Q | E | F | W | M | V | L | P | K | A | E | I | P | H | I | K | A | K | Y | T | L | D | G | K | E | L | T | A | P | I | S | A | H | Q | R | V | G |
Query Conservation |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
Template Sequence |   |
D | H | X | K | X | F | N | Y | V | F | E | H | Y | Q | T | Y | L | I | A | K | D | I | . |
. |
. |
. |
. |
. |
P | K | L | K | G | T | F | Y | E | S | K | A | F | I | K | R | D | I | T | Y | L | L | T | E | E | E | K | E | N | V | K | I | N | T | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | G | G | G | T | T | S | T | T | T | T | T |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
  |
  |   |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | I | E | L | Y | D | R | D | K | Q | V | A | H | W | P | L | V | T | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|   |
|   |
|   |   |   |
Template Sequence |   |
H | X | E | I | X | F | N | D | A | T | I | A | K | V | P | I | Y | Y | E |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
334 | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . |
  |